Related references
Note: Only part of the references are listed.IFN-I signaling in cancer: the connection with dysregulated Insulin/IGF axis
Veronica Vella et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2022)
Differential expression of insulin receptor substrate-1(IRS-1) in visceral and subcutaneous adipose depots of morbidly obese subjects undergoing bariatric surgery in a tertiary care center in north India; SNP analysis and correlation with metabolic profile
Mukti Sharma et al.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2021)
GNG12 regulates PD-L1 expression by activating NF-κB signaling in pancreatic ductal adenocarcinoma
Juan Li et al.
FEBS OPEN BIO (2020)
Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure
Albert Kwok et al.
MOLECULAR METABOLISM (2020)
Insulin receptor endocytosis in the pathophysiology of insulin resistance
Catherine Hall et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Down-Regulation of Ribosomal Protein RPS21 Inhibits Invasive Behavior of Osteosarcoma Cells Through the Inactivation of MAPK Pathway
Wang Tao et al.
CANCER MANAGEMENT AND RESEARCH (2020)
Modulation of Obesity and Insulin Resistance by the Redox Enzyme and Adaptor Protein p66Shc
Stefano Ciciliot et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Distinct Functions for Mammalian CLASP1 and-2 During Neurite and Axon Elongation
Carmen Laura Sayas et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Identification of candidate diagnostic and prognostic biomarkers for human prostate cancer: RPL22L1 and RPS21
Zumu Liang et al.
MEDICAL ONCOLOGY (2019)
SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling
Charlene Niogret et al.
FRONTIERS IN IMMUNOLOGY (2019)
Insulin receptor plays a central role in skin carcinogenesis by regulating cytoskeleton assembly
Galina Weingarten et al.
FASEB JOURNAL (2019)
Emerging Mechanisms of Insulin-Mediated Antiviral Immunity in Drosophila melanogaster
Chasity E. Trammell et al.
FRONTIERS IN IMMUNOLOGY (2019)
Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action
Atefeh Rabiee et al.
CELLULAR SIGNALLING (2018)
Proteome-wide identification of ubiquitin interactions using UbIA-MS
Xiaofei Zhang et al.
NATURE PROTOCOLS (2018)
Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation
Manoj K. Gupta et al.
MOLECULAR METABOLISM (2018)
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
Antonino Belfiore et al.
ENDOCRINE REVIEWS (2017)
The role of glucocorticoid receptors in metabolic syndrome and psychiatric illness
Andreas G. Moraitis et al.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2017)
Angiomotin-like 2 interacts with and negatively regulates AKT
H. Han et al.
ONCOGENE (2017)
Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells
Veronica Vella et al.
ONCOTARGET (2017)
CRL4DCAF8 Ubiquitin Ligase Targets Histone H3K79 and Promotes H3K9 Methylation in the Liver
Gaofeng Li et al.
CELL REPORTS (2017)
The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition
Ji Hoon Oh et al.
SCIENTIFIC REPORTS (2017)
Hedgehog Signaling: From Basic Biology to Cancer Therapy
Fujia Wu et al.
CELL CHEMICAL BIOLOGY (2017)
SHIP2: Structure, Function and Inhibition
Mark P. Thomas et al.
CHEMBIOCHEM (2017)
Divergent Roles of IRS (Insulin Receptor Substrate) 1 and 2 in Liver and Skeletal Muscle
Sabine Sarah Eckstein et al.
CURRENT MEDICINAL CHEMISTRY (2017)
EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice
Zara Zelenko et al.
ENDOCRINE-RELATED CANCER (2016)
An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling
Arunachalam Vinayagam et al.
CELL REPORTS (2016)
XB130: A novel adaptor protein in cancer signal transduction
Ruiyao Zhang et al.
BIOMEDICAL REPORTS (2016)
Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation
Medchalmi Swetha et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans
Stefano Ciciliot et al.
DIABETOLOGIA (2015)
Ribosomal proteins: functions beyond the ribosome
Xiang Zhou et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2015)
mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3
Anna Gebhardt et al.
NATURE COMMUNICATIONS (2015)
Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion
Ada Pesapane et al.
ONCOTARGET (2015)
Novel cross-talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses
Roberta Malaguarnera et al.
ONCOTARGET (2015)
The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells
Roberta Malaguarnera et al.
FRONTIERS IN ENDOCRINOLOGY (2014)
RPS12-specific shRNA inhibits the proliferation, migration of BGC823 gastric cancer cells with S100A4 as a downstream effector
Danqi Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Attenuated Pik3r1 Expression Prevents Insulin Resistance and Adipose Tissue Macrophage Accumulation in Diet-Induced Obese Mice
Carrie E. McCurdy et al.
DIABETES (2012)
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
K. D. Copps et al.
DIABETOLOGIA (2012)
Proinsulin Binds with High Affinity the Insulin Receptor Isoform A and Predominantly Activates the Mitogenic Pathway
Roberta Malaguarnera et al.
ENDOCRINOLOGY (2012)
Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes
Stephan Singer et al.
MOLECULAR CELL (2012)
The Shc locus regulates insulin signaling and adiposity in mammals
Alexey A. Tomilov et al.
AGING CELL (2011)
Insulin receptor and cancer
Antonino Belfiore et al.
ENDOCRINE-RELATED CANCER (2011)
RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway
Feng Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Insulin Receptor Isoforms and Insulin-Like Growth Factor Receptor in Human Follicular Cell Precursors from Papillary Thyroid Cancer and Normal Thyroid
Roberta Malaguarnera et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Research Resource: New and Diverse Substrates for the Insulin Receptor Isoform A Revealed by Quantitative Proteomics After Stimulation With IGF-II or Insulin
Alaide Morcavallo et al.
MOLECULAR ENDOCRINOLOGY (2011)
The Insulin Receptor: A New Target for Cancer Therapy
Roberta Malaguarnera et al.
Frontiers in Endocrinology (2011)
The p85β regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling
Jiman He et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
WAVE2 targeting to phosphatidylinositol 3,4,5-triphosphate mediated by insulin receptor substrate p53 through a complex with WAVE2
Kazuhide Takahashi et al.
CELLULAR SIGNALLING (2010)
The Ca2+-calmodulin-dependent kinase II is activated in papillary thyroid carcinoma (PTC) and mediates cell proliferation stimulated by RET/PTC
Maria Rosaria Rusciano et al.
ENDOCRINE-RELATED CANCER (2010)
The Cdc42-interacting Protein-4 (CIP4) Gene Knock-out Mouse Reveals Delayed and Decreased Endocytosis
Yanming Feng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
Jean-Francois Tanti et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
Differential Signaling Activation by Insulin and Insulin-Like Growth Factors I and II upon Binding to Insulin Receptor Isoform A
Antonella Sacco et al.
ENDOCRINOLOGY (2009)
Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway
Fiona C. McGillicuddy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis
Armen Parsyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation
Roberta Malaguarnera et al.
MOLECULAR CANCER RESEARCH (2008)
Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling
Claire Chaussade et al.
BIOCHEMICAL JOURNAL (2007)
The polycomb group protein Suz12 is required for embryonic stem cell differentiation
Diego Pasini et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
The role of Shp2 (PTPN11) in cancer
M. Golam Mohi et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
The role of insulin receptor isoforms and hybrid Insulin/IGF-I receptors in human cancer
Antonino Belfiore
CURRENT PHARMACEUTICAL DESIGN (2007)
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
Juri Rappsilber et al.
NATURE PROTOCOLS (2007)
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis
Lei Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling
Zachary A. Knight et al.
CELL (2006)
NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
L Haren et al.
JOURNAL OF CELL BIOLOGY (2006)
A pharmacological map of the PI3-K family defines a role for p110 alpha in insulin signaling
Zachary A. Knight et al.
CELL (2006)
Insulin receptor signals regulating GLUT4 translocation and act in dynamics
Makoto Kanzaki
ENDOCRINE JOURNAL (2006)
The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer
J Luo et al.
CELL CYCLE (2005)
RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at tyrosines 1250 and 1251
PA Kiely et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice
SM Brachmann et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation
Y Leng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Muscle regeneration and myogenic differentiation defects in mice lacking TIS7
SK Vadivelu et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Abi1 is essential for the formation and activation of a WAVE2 signalling complex
M Innocenti et al.
NATURE CELL BIOLOGY (2004)
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation
A Steffen et al.
EMBO JOURNAL (2004)
Isoform-specific insulin receptor signaling involves different plasma membrane domains
S Uhles et al.
JOURNAL OF CELL BIOLOGY (2003)
Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A
G Pandini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Interaction of filamin A with the insulin receptor alters insulin-dependent activation of the mitogen-activated protein kinase pathway
HJ He et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP
GOC Cory et al.
MOLECULAR CELL (2003)
In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A
L Sciacca et al.
ONCOGENE (2002)
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved
G Pandini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes
L Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
S Eden et al.
NATURE (2002)
RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact extracellular matrix
U Hermanto et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase
K Ueki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
A Diefenbach et al.
NATURE (2001)