4.5 Review

Targeting inflammation: a potential approach for the treatment of depression

Related references

Note: Only part of the references are listed.
Article Psychiatry

The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression

Conor W. McDonnell et al.

Summary: WKY rats are a valuable preclinical model of depression, with their depressive-like phenotype improved by ketamine but with transient side effects. This model helps in investigating novel antidepressant drugs.

FRONTIERS IN PSYCHIATRY (2021)

Review Endocrinology & Metabolism

Depression in type 2 diabetes: A systematic review and meta-analysis of blood inflammatory markers

Michelle M. Nguyen et al.

Summary: This study found that individuals with type 2 diabetes and comorbid depression had higher levels of C-reactive protein and interleukin-6 in their blood, while lower levels of brain derived neurotrophic factor compared to those without depression.

PSYCHONEUROENDOCRINOLOGY (2021)

Review Biochemistry & Molecular Biology

The Role of BDNF in Experimental and Clinical Traumatic Brain Injury

David Gustafsson et al.

Summary: BDNF plays a crucial role in neural repair and regeneration, making it a focus of TBI research. Studies have shown varied effects on BDNF expression based on different experimental setups and interventions. Clinical research emphasizes the significance of BDNF polymorphism in outcomes, highlighting its protective role.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Identification of transcriptome alterations in the prefrontal cortex, hippocampus, amygdala and hippocampus of suicide victims

Daniela Glavan et al.

Summary: Suicide is a major cause of death globally, and the underlying neurobiological pathology remains largely unknown. Research has identified gene expression changes in suicide completers related to various disorders such as neurodevelopmental disorders, motivation, addiction, major depression, schizophrenia, and others.

SCIENTIFIC REPORTS (2021)

Review Immunology

Circadian Clock Regulates Inflammation and the Development of Neurodegeneration

Xiao-Lan Wang et al.

Summary: The circadian clock plays a crucial role in regulating key physiological processes and maintaining homeostasis, with disruptions affecting immune response, brain function, and neurodegeneration. By controlling the clock mechanisms in immune and brain cells, as well as systemic inflammation, the circadian system may offer potential targets for preventing and treating inflammation and neurodegenerative diseases.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Review Physiology

The role of inflammation in hypertension: novel concepts

David M. Patrick et al.

Summary: Hypertension is a major modifiable risk factor for cardiovascular disease, with inflammation playing a crucial role in its development and maintenance; recent discoveries have highlighted the link between sodium-induced immune cell activation and hypertension pathogenesis, the key role of inflammation in the genesis of hypertension, as well as previously uncharacterized immune cell populations.

CURRENT OPINION IN PHYSIOLOGY (2021)

Review Pharmacology & Pharmacy

Role of oxidative stress in depression

Shvetank Bhatt et al.

DRUG DISCOVERY TODAY (2020)

Article Pharmacology & Pharmacy

Ketamine as an antidepressant: overview of its mechanisms of action and potential predictive biomarkers

Dmitriy Matveychuk et al.

THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY (2020)

Article Psychiatry

Cross-Cultural Psychometric Properties of the Hamilton Depression Rating Scale

Erik Vindbjerg et al.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2019)

Review Psychiatry

Is the HPA Axis as Target for Depression Outdated, or Is There a New Hope?

Andreas Menke

FRONTIERS IN PSYCHIATRY (2019)

Review Immunology

The Role of Inflammation in Depression and Fatigue

Chieh-Hsin Lee et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Psychiatry

Minocycline alters behavior, microglia and the gut microbiome in a trait-anxiety-dependent manner

Anna K. Schmidtner et al.

TRANSLATIONAL PSYCHIATRY (2019)

Review Biochemistry & Molecular Biology

Cytokines in Inflammatory Disease

Shinwan Kany et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Psychiatry

Rheumatoid arthritis and depression: an inflammatory perspective

Louis Nerurkar et al.

LANCET PSYCHIATRY (2019)

Review Biochemistry & Molecular Biology

Cellular and Molecular Mechanisms Underlying Non-Pharmaceutical Ischemic Stroke Therapy in Aged Subjects

Raluca Elena Sandu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Clinical Neurology

Neural basis of major depressive disorder: Beyond monoamine hypothesis

Shuken Boku et al.

PSYCHIATRY AND CLINICAL NEUROSCIENCES (2018)

Review Geriatrics & Gerontology

Oxidative stress, aging, and diseases

Ilaria Liguori et al.

CLINICAL INTERVENTIONS IN AGING (2018)

Review Endocrinology & Metabolism

Depression in people with type 2 diabetes: current perspectives

Lina Darwish et al.

DIABETES METABOLIC SYNDROME AND OBESITY-TARGET & THERAPY (2018)

Review Psychiatry

Genetics Factors in Major Depression Disease

Maria Shadrina et al.

FRONTIERS IN PSYCHIATRY (2018)

Article Psychiatry

DSM-5 Criteria and Depression Severity: Implications for Clinical Practice

Julio C. Tolentino et al.

FRONTIERS IN PSYCHIATRY (2018)

Review Psychiatry

Recognition and Treatment of Cognitive Dysfunction in Major Depressive Disorder

Hannah Zuckerman et al.

FRONTIERS IN PSYCHIATRY (2018)

Editorial Material Neurosciences

Antidepressant effects of ketamine and the roles of AMPA glutamate receptors and other mechanisms beyond NMDA receptor antagonism

Lily R. Aleksandrova et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2017)

Article Medicine, General & Internal

Obesity and inflammation: the linking mechanism and the complications

Mohammed S. Ellulu et al.

ARCHIVES OF MEDICAL SCIENCE (2017)

Review Medicine, Legal

Metabolism and metabolomics of ketamine: a toxicological approach

Ricardo Jorge Dinis-Oliveira

FORENSIC SCIENCES RESEARCH (2017)

Review Neurosciences

Stress Effects on Neuronal Structure: Hippocampus, Amygdala, and Prefrontal Cortex

Bruce S. McEwen et al.

NEUROPSYCHOPHARMACOLOGY (2016)

Article Pharmacology & Pharmacy

Role of Aspirin and Dexamethasone against Experimentally Induced Depression in Rats

Shailendra Bhatt et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2016)

Review Peripheral Vascular Disease

Hypertension as an autoimmune and inflammatory disease

Yalcin Solak et al.

HYPERTENSION RESEARCH (2016)

Review Clinical Neurology

Circadian rhythms and attention deficit hyperactivity disorder: The what, the when and the why

Andrew N. Coogan et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2016)

Article Biology

Cyclooxygenase-2 inhibition reduces stress-induced affective pathology

Joyonna Carrie Gamble-George et al.

eLife (2016)

Editorial Material Neurosciences

Why is depression more prevalent in women?

Paul R. Albert

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2015)

Review Cell Biology

Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology

Raluca Elena Sandu et al.

NEURAL REGENERATION RESEARCH (2015)

Article Chemistry, Multidisciplinary

Improvement of solubility of celecoxib by inclusion in MCM-41 mesoporous silica: drug loading and release

Sahika Gunaydin et al.

TURKISH JOURNAL OF CHEMISTRY (2015)

Meeting Abstract Rheumatology

THE EFFECTS OF INFLIXIMAB TREATMENT ON DEPRESSION, ANXIETY AND SLEEP DISORDERS IN PATIENTS WITH ANKYLOSING SPONDYLITIS

E. D. Ersozlu Bozkirli et al.

ANNALS OF THE RHEUMATIC DISEASES (2014)

Article Psychiatry

Cognitive Dysfunction in Major Depressive Disorder: Effects on Psychosocial Functioning and Implications for Treatment

Raymond W. Lam et al.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2014)

Review Biochemistry & Molecular Biology

Therapeutic Effects of Melatonin Receptor Agonists on Sleep and Comorbid Disorders

Moshe Laudon et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Review Neurosciences

Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings)

Georges Mion et al.

CNS NEUROSCIENCE & THERAPEUTICS (2013)

Review Psychology, Clinical

CYTOKINE TARGETS IN THE BRAIN: IMPACT ON NEUROTRANSMITTERS AND NEUROCIRCUITS

Andrew H. Miller et al.

DEPRESSION AND ANXIETY (2013)

Article Psychology, Biological

Effects of long-term etanercept treatment on anxiety- and depression-like neurobehaviors in rats

Dilek Bayramgurler et al.

PHYSIOLOGY & BEHAVIOR (2013)

Article Psychology, Clinical

PROINFLAMMATORY AND RESILIENCY PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION

Jose M. Martinez et al.

DEPRESSION AND ANXIETY (2012)

Article Biotechnology & Applied Microbiology

Celecoxib pathways: pharmacokinetics and pharmacodynamics

Li Gong et al.

PHARMACOGENETICS AND GENOMICS (2012)

Review Cardiac & Cardiovascular Systems

Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease

Lina Badimon et al.

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE (2012)

Article Psychiatry

Increased xanthine oxidase in the thalamus and putamen in depression

Tanja Maria Michel et al.

WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2010)

Review Environmental Sciences

Suicidal Behavior and Alcohol Abuse

Maurizio Pompili et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2010)

Article Psychiatry

Cognitive Behavioral Therapy for Mood Disorders: Efficacy, Moderators and Mediators

Ellen Driessen et al.

PSYCHIATRIC CLINICS OF NORTH AMERICA (2010)

Review Cell Biology

Vascular endothelium in atherosclerosis

Anca V. Sima et al.

CELL AND TISSUE RESEARCH (2009)

Article Cell Biology

Cyclooxygenase in normal human tissues - is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?

Nina Zidar et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)

Article Biochemistry & Molecular Biology

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

J. C. O'Connor et al.

MOLECULAR PSYCHIATRY (2009)

Article Psychiatry

Depression-related variation in brain morphology over 3 years -: Effects of stress?

Thomas S. Frodl et al.

ARCHIVES OF GENERAL PSYCHIATRY (2008)

Article Medicine, Research & Experimental

Does minocycline have antidepressant effect?

Chi-Un Pae et al.

BIOMEDICINE & PHARMACOTHERAPY (2008)

Review Clinical Neurology

Circadian rhythm disturbances in depression

Anne Germain et al.

HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL (2008)

Article Multidisciplinary Sciences

The molecular neurobiology of depression

Vaishnav Krishnan et al.

NATURE (2008)

Review Neurosciences

From inflammation to sickness and depression: when the immune system subjugates the brain

Robert Dantzer et al.

NATURE REVIEWS NEUROSCIENCE (2008)

Review Medicine, General & Internal

Mechanisms of disease: Major depressive disorder

R. H. Belmaker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Review Gastroenterology & Hepatology

Infliximab use in children and adolescents with inflammatory bowel disease

Lissy de Ridder et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2007)

Article Neurosciences

Cerebral blood flow in immediate and sustained anxiety

Gregor Hasler et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Psychiatry

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression

Carlos A. Zarate et al.

ARCHIVES OF GENERAL PSYCHIATRY (2006)

Review Infectious Diseases

Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines

Kenneth N. Agwuh et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2006)

Article Psychiatry

Toward a comprehensive developmental model for major depression in men

KS Kendler et al.

AMERICAN JOURNAL OF PSYCHIATRY (2006)

Article Endocrinology & Metabolism

Neuroactive steroids in depression and anxiety disorders: Clinical studies

Daniela Eser et al.

NEUROENDOCRINOLOGY (2006)

Review Pharmacology & Pharmacy

GABA and glutamate systems as therapeutic targets in depression and mood disorders

SF Kendell et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2005)

Article Clinical Neurology

Cu, Zn- and Mn-superoxide dismutase levels in brains of patients with schizophrenic psychosis

TM Michel et al.

JOURNAL OF NEURAL TRANSMISSION (2004)

Article Pharmacology & Pharmacy

Infliximab treatment of rheumatoid arthritis and Crohn's disease

IK Nahar et al.

ANNALS OF PHARMACOTHERAPY (2003)

Article Psychiatry

Untreated depression and hippocampal volume loss

YI Sheline et al.

AMERICAN JOURNAL OF PSYCHIATRY (2003)

Article Psychiatry

Toward a comprehensive developmental model for major depression in women

KS Kendler et al.

AMERICAN JOURNAL OF PSYCHIATRY (2002)

Review Psychiatry

Genetic epidemiology of major depression: Review and meta-analysis

PF Sullivan et al.

AMERICAN JOURNAL OF PSYCHIATRY (2000)