Journal
MENDELEEV COMMUNICATIONS
Volume 32, Issue 5, Pages 680-682Publisher
ELSEVIER
DOI: 10.1016/j.mencom.2022.09.038
Keywords
phenolic antioxidants; cis-imidazolines; polyphenolic compounds; quinonoid oxidation; propyl gallate; superoxide anion; ionol analogues
Categories
Funding
- Russian Science Foundation
- Russian Foundation for Basic Research
- (chemiluminescent method)
- [22-23-00295]
- [20-03-00915A]
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New effective antioxidants of cis-2,4,5-tris(hydroxyaryl)-imidazoline type were synthesized from aromatic aldehydes and ammonia. Their antioxidant activity against hydroxyl radical and superoxide radical anion in physiological media was measured, and oxidation potentials were determined by cyclic voltammetry. The lead compound with 3,4,5-hydroxyphenyl moieties exhibited 3.5 times higher activity compared to Trolox.
New effective antioxidants of cis-2,4,5-tris(hydroxyaryl)-imidazoline type were assembled from aromatic aldehydes and ammonia. Their antioxidant activity was measured against hydroxyl radical and superoxide radical anion in physiological media, and oxidation potentials were measured by cyclic voltammetry. The lead compound bearing 3,4,5-hydroxyphenyl moieties showed activity 3.5 times higher compared to Trolox.
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