Pregnancy and lactation-associated osteoporosis in a Systemic Lupus Erythematosus patient

Review Orthopedics

Pregnancy- and lactation-associated osteoporosis with vertebral fractures: a systematic review

Ying Qian et al.

Summary: Pregnancy and lactation-related osteoporosis (PLO) with vertebral fractures is a rare clinical condition that mainly affects older and thinner pregnant women, often occurring in the first pregnancy. Patients typically experience back pain in the late stages of pregnancy and early postpartum period, with most vertebral fractures happening at the L2, L1, and T12 levels.

BMC MUSCULOSKELETAL DISORDERS (2021)

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Article Endocrinology & Metabolism

Influence of denosumab on bone mineral density in a severe case of pregnancy-associated osteoporosis

U. Stumpf et al.

Summary: Pregnancy and lactation-associated osteoporosis (PLO) is a rare but severe disease with potential risks. Treatment with denosumab in PLO patients demonstrated significant improvement in bone mineral density and prevention of further fractures, but further research is needed to fully understand its effects.

OSTEOPOROSIS INTERNATIONAL (2021)

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Review Endocrinology & Metabolism