Evidence-based impact projections of single-dose human papillomavirus vaccination in India: a modelling study

Article Public, Environmental & Occupational Health

Cervical cancer screening programmes and age-specific coverage estimates for 202 countries and territories worldwide: a review and synthetic analysis

Laia Bruni et al.

Lancet Global Health (2022)

Editorial Material Public, Environmental & Occupational Health

Invited Commentary: Rethinking Cervical Cancer Elimination in Terms of Lifetime Risk Rather Than Arbitrarily Defined Age-Standardized Incidence Rates

Talia Malagon et al.

Summary: Research suggests that standardized lifetime risk may be a more appropriate public health target for cervical cancer elimination. Age-standardized incidence rates have limitations compared to standardized lifetime risk.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2021)

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Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

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Article Medicine, General & Internal

The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a register-based observational study

Milena Falcaro et al.

Summary: A study in England found a significant reduction in cervical cancer and CIN3 incidence in young women after the introduction of the HPV immunisation programme, especially in those vaccinated at age 12-13. The programme has successfully almost eliminated cervical cancer in women born since September 1, 1995.

LANCET (2021)

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Article Oncology

Vaccine efficacy against persistent human papillomavirus (HPV) 16/18 infection at 10 years after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre, prospective, cohort study

Partha Basu et al.

Summary: This study in India compared the efficacy of single dose HPV vaccine with two and three doses in protecting against persistent HPV 16 and 18 infection over a 10-year period. The research found that a single dose of the vaccine provided similar protection against these infections as two or three doses, which are responsible for nearly 70% of cervical cancers.

LANCET ONCOLOGY (2021)

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Article Public, Environmental & Occupational Health

Global estimates of expected and preventable cervical cancers among girls born between 2005 and 2014: a birth cohort analysis

Maxime Bonjour et al.

Summary: The World Health Organization has launched an initiative to eliminate cervical cancer as a public health problem. Estimates show that without vaccination, the burden of cervical cancer is expected to reach 11.6 million cases by 2094, with the majority of the burden concentrated in African and Asian countries. HPV vaccination targeting specific types could prevent millions of cases, providing important information for public health decision makers.

LANCET PUBLIC HEALTH (2021)

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Article Infectious Diseases

Optimal human papillomavirus vaccination strategies to prevent cervical cancer in low-income and middle-income countries in the context of limited resources: a mathematical modelling analysis

Melanie Drolet et al.

Summary: The study modeled various HPV vaccination strategies in LMICs and found that vaccination could help eliminate cervical cancer in India, Vietnam, and Nigeria. Compared with no vaccination, strategies that involved vaccinating girls aged 9-14 years with two doses were predicted to be the most efficient and cost-effective.

LANCET INFECTIOUS DISEASES (2021)

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Article Medicine, General & Internal