A Counterion/Ligand-Tuned Chemo- and Enantioselective Copper- Catalyzed Intermolecular Radical 1,2-Carboamination of Alkenes

Article Chemistry, Multidisciplinary

Design of Hemilabile N,N,N-Ligands in Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Benzyl/Propargyl Halides with Alkenylboronate Esters

Peng-Fei Wang et al.

Summary: In this study, a copper/chiral N,N,N-ligand catalytic system was developed for the enantioconvergent cross-coupling of benzyl/propargyl halides with alkenylboronate esters, providing enantiocontrol over highly reactive alkyl radicals.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Photoinduced, Copper-Catalyzed Enantioconvergent Alkylations of Anilines by Racemic Tertiary Electrophiles: Synthesis and Mechanism

Hyungdo Cho et al.

Summary: Transition-metal catalysis of substitution reactions of alkyl electrophiles by nitrogen nucleophiles is an important strategy for synthesizing higher-order amines and controlling their stereochemistry. This study reports the photo-induced enantioconvergent coupling of racemic tertiary alkyl electrophiles with aniline nucleophiles using a readily accessible chiral copper catalyst. The mechanism of this catalytic process has been elucidated using various tools, leading to the identification of key copper-based intermediates in the proposed cycle.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Mechanism-based ligand design for copper-catalysed enantioconvergent C(sp3)-C(sp) cross-coupling of tertiary electrophiles with alkynes

Fu-Li Wang et al.

Summary: In contrast to the well-established enantioconvergent radical C(sp(3))-C cross-coupling, the coupling of tertiary electrophiles to forge all-carbon quaternary stereocentres remains unexplored. Here, we demonstrate a general copper-catalysed enantioconvergent C(sp(3))-C(sp) cross-coupling using rational design of chiral ligands. This protocol provides a practical platform for the construction of chiral carbon building blocks of interest in organic synthesis.

NATURE CHEMISTRY (2022)

Add to Collection

Article Chemistry, Organic

Introduction of Lipophilic Side Chains to NH-Sulfoximines by Palladium Catalysis Under Blue Light Irradiation

Ding Ma et al.

Summary: Palladium catalysis under blue light enables the conversion of NH-sulfoximines into products with long lipophilic side chains. This three-component reaction involves both radicals and organo-metallic intermediates, resulting in moderate to good yields of the products.

ORGANIC LETTERS (2022)

Add to Collection

Article Chemistry, Physical

Cu-Catalyzed C(sp3)-N Coupling and Alkene Carboamination Enabled by Ligand-Promoted Selective Hydrazine Transfer to Alkyl Radicals

Dengfu Lu et al.

Summary: In this study, a unique effective amination reagent was discovered that can selectively deliver an N-nucleophile onto an alkyl radical in Cu-catalyzed reactions. This method is applicable to various electron-deficient and electron-rich radicals, and enables the direct formation of C-N bonds and carboamination of alkenes.

ACS CATALYSIS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Ligand Development for Copper-Catalyzed Enantioconvergent Radical Cross-Coupling of Racemic Alkyl Halides

Xiao-Yang Dong et al.

Summary: This article mainly introduces the research progress on enantioconvergent radical cross-coupling reactions. Compared with chiral nickel catalysts, the study of copper-catalyzed enantioconvergent radical cross-coupling is less explored, primarily due to the weak reducing capability of copper. In recent years, researchers have been dedicated to developing chiral ligands for copper-catalyzed enantioconvergent radical cross-coupling to address the issues of enantiocontrol and reaction initiation speed.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

Add to Collection

Review Chemistry, Organic

Recent Advances in N-Arylation of NH-Sulfoximines and Their Applications

Xue Li et al.

Summary: Sulfoximines play a significant role in organic chemistry as chiral auxiliaries, ligands, and organocatalysts. They are also important intermediates for synthesizing heterocyclic compounds. Due to their unique bioactivities, sulfoximines have been developed as privileged pharmacophores and widely utilized in pharmaceutical chemistry and agriculture. This article reviews the synthetic methods of NAr-sulfoximines through the direct arylation of NH-sulfoximines, highlighting their advantages, such as atom-economics, mild conditions, and step-economics. The applications of these methods in the synthesis of bioactive molecules and ligands for transition-metal catalysts are also discussed.

CHINESE JOURNAL OF ORGANIC CHEMISTRY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Copper-Catalyzed Enantioconvergent Cross-Coupling of Racemic Alkyl Bromides with Azole C(sp2)-H Bonds

Xiao-Long Su et al.

Summary: The development of enantioconvergent cross-coupling of racemic alkyl halides with heteroarene C(sp(2))-H bonds has been achieved using a copper(I)/cinchona-alkaloid-derived N,N,P-ligand catalytic system, leading to high enantioselectivity of alpha-chiral alkylated heteroarenes, which show promise in drug discovery.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides

Lianqian Wu et al.

Summary: An unprecedented highly enantioselective radical azidation of acrylamides catalyzed by 1 mol% of a copper catalyst is reported. The use of a specific ligand is crucial for generating a monomeric Cu-II azide species for this highly enantioselective transformation.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective Alkylamination of Unactivated Alkenes under Copper Catalysis

Zibo Bai et al.

Summary: An enantioselective addition reaction of various alkyl groups to unactivated internal alkenes under Cu catalysis has been developed, leading to high yields of β-lactams featuring two contiguous stereocenters with excellent enantioselectivity. Mechanistic studies suggest that a nucleophilic addition of the alkyl radical to Cu-II-coordinated alkene is the enantio-determining step.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Physical

Iron-catalysed asymmetric carboazidation of styrenes

Liang Ge et al.

Summary: The study reports a radical asymmetric carboazidation of olefins via an iron-catalysed group transfer mechanism, providing valuable chiral halogenated organoazides from inexpensive industrial chemical feedstocks. The method is supported by mechanistic studies and is expected to inspire further development of enantioselective radical reactions.

NATURE CATALYSIS (2021)

Add to Collection

Article Multidisciplinary Sciences

Stereodivergent atom-transfer radical cyclization by engineered cytochromes P450

Qi Zhou et al.

Summary: Naturally occurring enzymes can be evolved to generate efficient biocatalysts for unnatural reactions. By repurposing cytochromes P450, stereoselective atom-transfer radical cyclization can be catalyzed, allowing for enantio- and diastereodivergent radical catalysis with substantial stereocontrol. This evolvable metalloenzyme platform offers a promising solution for asymmetric catalysis involving fleeting radical intermediates.

SCIENCE (2021)

Add to Collection

Article Chemistry, Physical

Chiral Allylic Amine Synthesis Enabled by the Enantioselective CpXRh(III)-Catalyzed Carboaminations of 1,3-Dienes

Liexin Wu et al.

Summary: The study presents a (CpRh)-Rh-X(III)-catalyzed enantioselective intermolecular carboamination of 1,3-dienes, allowing the direct synthesis of chiral allylic amines with phenol functionalities under mild conditions. The mechanistic pathway involves an unusual Rh(III)-Rh(I)-Rh(III) catalytic cycle and has shown potential in the derivation of natural products and bioactive complexes.

ACS CATALYSIS (2021)

Add to Collection

Article Chemistry, Physical

Oxidative Three-Component Carboamination of Vinylarenes with Alkylboronic Acids

Samuel N. Gockel et al.

Summary: This study developed an oxidative carboamination protocol utilizing alkylboronic acids as carbon-centered radical precursors to efficiently produce a variety of functionalized amines, with a broad scope in vinylarenes, amines, and alkylboronic acids. Preliminary mechanistic studies revealed a single-electron oxidation of the alkylboronic acid to generate a carbon-centered radical intermediate that undergoes C-N bond formation across the olefin.

ACS CATALYSIS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Metalloradical activation of carbonyl azides for enantioselective radical aziridination

Xavier Riart-Ferrer et al.

Summary: TrocN(3) serves as a potent nitrogen radical precursor for radical olefin aziridination catalyzed by a new Co(II)-based catalytic system, with the cobalt(II) complex of a D-2-symmetric chiral amidoporphyrin proving to be an efficient catalyst. This represents the first example of asymmetric intermolecular olefin aziridination using carbonyl azides as the nitrogen source, allowing for the enantioselective synthesis of various chiral amine derivatives.

CHEM (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Recent advances in radical chemistry proceeding through pro-aromatic radicals

Anup Bhunia et al.

Summary: This review discusses the use of pro-aromatic compounds as carbon- and heteroatom-radical precursors, highlighting the underlying principle of gaining aromaticity for pro-aromatic radicals. The compounds can be easily transformed into radicals, which can then engage in hydrogen atom or radical functional group transfer chemistry.

CHEM (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Iron-Catalyzed Enantioselective Radical Carboazidation and Diazidation of α,β-Unsaturated Carbonyl Compounds

Wen Liu et al.

Summary: This study presents an efficient enantioselective radical carboazidation and diazidation reaction of α,β-unsaturated ketones and amides catalyzed by chiral N,N'-dioxide/Fe(OTf)(2) complexes, enabling the preparation of chiral compounds from substituted alkenes. Control experiments and mechanistic studies confirmed the radical pathway in the reaction process.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Visible Light Induced Cu-Catalyzed Asymmetric C(sp3)-H Alkylation

Rupeng Qi et al.

Summary: Asymmetric functionalization of C-H is a attractive strategy in asymmetric synthesis, and photoredox catalysis has emerged as an efficient way to synthesize organic compounds under mild conditions.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioconvergent Cu-Catalyzed Radical C-N Coupling of Racemic Secondary Alkyl Halides to Access α-Chiral Primary Amines

Yu-Feng Zhang et al.

Summary: This study demonstrates the successful use of sulfoximines as ammonia surrogates for enantioconvergent radical C-N coupling with diverse racemic secondary alkyl halides, achieving high yields and enantioselectivity. The obtained alpha-chiral primary amines can be converted to various synthetic building blocks, ligands, and drugs, highlighting the potential of enantioconvergent radical cross-coupling as a general chiral carbon-heteroatom formation strategy.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Add to Collection

Article Multidisciplinary Sciences

Photoinduced copper-catalysed asymmetric amidation via ligand cooperativity

Caiyou Chen et al.

Summary: The study describes a method for enantioselective substitution of unactivated alkyl electrophiles using a copper-based photoinduced catalyst system, expanding the scope of enantioselective N-substitution reactions to include unactivated electrophiles.

NATURE (2021)

Add to Collection

Article Chemistry, Physical

Ligand-Enabled Copper(I)-Catalyzed Asymmetric Radical C(sp(3))-C Cross-Coupling Reactions

Huan Zhou et al.

Summary: Transition-metal-catalyzed asymmetric C-(sp(3))-C cross-coupling is an efficient method for the rapid synthesis of enantioenriched molecules. Chiral copper catalysts have been designed to promote a variety of asymmetric radical C(sp(3))-C cross-coupling reactions with high efficiency and enantioselectivity. The key to success lies in the design of chiral ligands to initiate the reaction and achieve enantiocontrol over the highly reactive prochiral alkyl radical species.

ACS CATALYSIS (2021)

Add to Collection

Article Chemistry, Physical

Rhodium-Catalyzed Regio-, Diastereo-, and Enantioselective Three-Component Carboamination of Dienes via C-H Activation

Ruijie Mi et al.

Summary: This study reports the rhodium-catalyzed enantioselective three-component coupling of arene, diene, and dioxazolone via C-H activation to produce chiral allylic amines. The electrophilic amination of the pi-allyl species is both regio- and enantio-determining in this carboamination reaction.

ACS CATALYSIS (2021)

Add to Collection

Review Chemistry, Organic

Recent developments in the difunctionalization of alkenes with C-N bond formation

Xiang Chen et al.

Summary: The difunctionalization of carbon-carbon double bonds is a powerful tool in synthetic chemistry to enhance the complexity of molecules by introducing two novel functional groups in one pot. Research on difunctionalization of alkenes involving the participation of a N source is a hotspot due to the broad existence of N-containing functional groups in various compounds, and further developments in this area are expected.

ORGANIC CHEMISTRY FRONTIERS (2021)

Add to Collection

Review Chemistry, Organic

Recent advances in aminative difunctionalization of alkenes

Ziying Wu et al.

Summary: This review outlines the major developments in transition metal-catalyzed or metal-free diamination, aminohalogenation, aminocarbonation, amino-oxidation, and aminoboronation reactions of alkenes from 2015-2020. It highlights the efficiency and advantages of the aminative difunctionalization of alkenes in synthesizing nitrogen-containing compounds, which are widely found in natural and synthetic products. The construction of C-N bonds from simple and easily available raw materials has been a topic of interest to chemists, especially in the synthesis of drugs.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

Add to Collection

Review Chemistry, Organic

Recent advances in the synthesis of alpha-amino ketones

Lewis A. T. Allen et al.

Summary: This review discusses the importance of the amino ketone motif in synthetic and medicinal chemistry, summarizing the recent increase in protocols developed. The methodologies are categorized by the requisite functionality in the starting material, emphasizing functional group compatibility and product substitution patterns. Applications to medicinal targets are highlighted, along with mechanistic details and a brief outlook for future development and emerging potential within this area.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Copper(I)-Catalyzed Asymmetric Reactions Involving Radicals

Qiang-Shuai Gu et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Photosensitized Intermolecular Carboimination of Alkenes through the Persistent Radical Effect

Tuhin Patra et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Pd-Catalyzed C-C, C-N, and C-O Bond-Forming Difunctionalization Reactions of Alkenes Bearing Tethered Aryl/Alkenyl Triflates

Derick R. White et al.

ISRAEL JOURNAL OF CHEMISTRY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Divergent Synthesis of Tunable Cyclopentadienyl Ligands and Their Application in Rh-Catalyzed Enantioselective Synthesis of Isoindolinone

Wen-Jun Cui et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective radical C-H amination for the synthesis of β-amino alcohols

Kohki M. Nakafuku et al.

NATURE CHEMISTRY (2020)

Add to Collection

Article Chemistry, Organic

Copper-Catalyzed Asymmetric Cyanation of Alkenes via Carbonyl-Assisted Coupling of Alkyl-Substituted Carbon-Centered Radicals

Song Zhou et al.

ORGANIC LETTERS (2020)

Add to Collection

Article Chemistry, Organic

Synthesis of Benzylureas and Related Amine Derivatives via Copper-Catalyzed Three-Component Carboamination of Styrenes

Jonathan J. Kennedy-Ellis et al.

ORGANIC LETTERS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioconvergent Amination of Racemic Tertiary C-H Bonds

Kai Lang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective Intermolecular Radical C-H Amination

Li-Mei Jin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Copper-Catalyzed Enantioconvergent Radical Suzuki-Miyaura C(sp3)-C(sp2) Cross-Coupling

Sheng-Peng Jiang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes

Joseph Derosa et al.

CHEMICAL SCIENCE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Pd/Xiang-Phos-catalyzed enantioselective intermolecular carboheterofunctionalization under mild conditions

Mengna Tao et al.

CHEMICAL SCIENCE (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Intermolecular radical carboamination of alkenes

Heng Jiang et al.

CHEMICAL SOCIETY REVIEWS (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Recent advances in copper-catalysed radical-involved asymmetric 1,2-difunctionalization of alkenes

Zhong-Liang Li et al.

CHEMICAL SOCIETY REVIEWS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Chiral Cyclopentadienyl Cobalt(III) Complexes Enable Highly Enantioselective 3d-Metal-Catalyzed C-H Functionalizations

Kristers Ozols et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Chemistry, Organic

Copper-Catalyzed Intermolecular Carboamination of Alkenes Induced by Visible Light

Yang Xiong et al.

ORGANIC LETTERS (2019)

Add to Collection

Review Biochemistry & Molecular Biology

Alkene Difunctionalization Using Hypervalent Iodine Reagents: Progress and Developments in the Past Ten Years

Ji Hoon Lee et al.

MOLECULES (2019)

Add to Collection

Article Multidisciplinary Sciences

Photoexcitation of flavoenzymes enables a stereoselective radical cyclization

Kyle F. Biegasiewicz et al.

SCIENCE (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination

Yang Hu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

An enzymatic platform for the asymmetric amination of primary, secondary and tertiary C(sp3)-H bonds

Yang Yang et al.

NATURE CHEMISTRY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

A general asymmetric copper-catalysed Sonogashira C(sp3)-C(sp) coupling

Xiao-Yang Dong et al.

NATURE CHEMISTRY (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Next-Generation D2-Symmetric Chiral Porphyrins for Cobalt(II)-Based Metalloradical Catalysis: Catalyst Engineering by Distal Bridging

Yang Hu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Cu-Catalyzed Three-Component Carboamination of Alkenes

Samuel N. Gockel et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Copper-Mediated Reversible Deactivation Radical Polymerization in Aqueous Media

Glen R. Jones et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Add to Collection

Article Multidisciplinary Sciences

Catalytic enantioselective Minisci-type addition to heteroarenes

Rupert S. J. Proctor et al.

SCIENCE (2018)

Add to Collection

Review Chemistry, Multidisciplinary

New Horizons of Photocatalytic Fluoromethylative Difunctionalization of Alkenes

Takashi Koike et al.

CHEM (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations

Fei Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

Add to Collection

Article Multidisciplinary Sciences

Quaternary stereocentres via an enantioconvergent catalytic SN1 reaction

Alison E. Wendlandt et al.

NATURE (2018)

Add to Collection

Article Chemistry, Organic

Stereoselective and Regioselective Synthesis of Heterocycles via Copper-Catalyzed Additions of Amine Derivatives and Alcohols to Alkenes

Sherry R. Chemler et al.

JOURNAL OF ORGANIC CHEMISTRY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Diastereodivergent Asymmetric Carboamination/Annulation of Cyclopropenes with Aminoalkenes by Chiral Lanthanum Catalysts

Huai-Long Teng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric Radical Bicyclization of Allyl Azidoformates via Cobalt(II)-Based Metalloradical Catalysis

Huiling Jiang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Iron-Catalyzed Carboamination of Olefins: Synthesis of Amines and Disubstituted β-Amino Acids

Bo Qian et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric Radical Cyclopropanation of Alkenes with In Situ Generated Donor-Substituted Diazo Reagents via Co(II)-Based Metalloradical Catalysis

Yong Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Enantioselective cyclizations and cyclization cascades of samarium ketyl radicals

Nicolas Kern et al.

NATURE CHEMISTRY (2017)

Add to Collection

Article Multidisciplinary Sciences

Oxidative 1,2-carboamination of alkenes with alkyl nitriles and amines toward γ-amino alkyl nitriles

Yan-Yun Liu et al.

NATURE COMMUNICATIONS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Palladium-Catalyzed Cascade sp2 C-H Functionalization/Intramolecular Asymmetric Allylation: From Aryl Ureas and 1,3-Dienes to Chiral Indolines

Shu-Sen Chen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Add to Collection

Review Chemistry, Organic

Copper Catalyzed Atom Transfer Radical Cyclization Reactions

Andrew J. Clark

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2016)

Add to Collection

Article Chemistry, Multidisciplinary

A Dual-Catalytic Strategy To Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes

Jin-Shun Lin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Add to Collection

Article Multidisciplinary Sciences

Asymmetric catalytic formation of quaternary carbons by iminium ion trapping of radicals

John J. Murphy et al.

NATURE (2016)

Add to Collection

Article Multidisciplinary Sciences

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

Quirin M. Kainz et al.

SCIENCE (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Enantioselective Catalysis of Photochemical Reactions

Richard Brimioulle et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Copper-catalyzed oxidative C(sp3)-H/N-H coupling of sulfoximines and amides with simple alkanes via a radical process

Fan Teng et al.

CHEMICAL COMMUNICATIONS (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric Pd-Catalyzed Alkene Carboamination Reactions for the Synthesis of 2-Aminoindane Derivatives

Derick R. White et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Add to Collection

Article Chemistry, Organic

Base-Induced Radical Carboamination of Nonactivated Alkenes with Aryldiazonium Salts

Stephanie Kindt et al.

ORGANIC LETTERS (2015)

Add to Collection

Article Chemistry, Multidisciplinary

The Photoredox-Catalyzed Meerwein Addition Reaction: Intermolecular Amino-Arylation of Alkenes

Durga Prasad Hari et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Add to Collection

Article Multidisciplinary Sciences

Asymmetric photoredox transition-metal catalysis activated by visible light

Haohua Huo et al.

NATURE (2014)

Add to Collection

Article Chemistry, Multidisciplinary

An organic thiyl radical catalyst for enantioselective cyclization

Takuya Hashimoto et al.

NATURE CHEMISTRY (2014)

Add to Collection

Article Chemistry, Organic

Iron-Catalyzed Hetero-Cross-Dehydrogenative Coupling Reactions of Sulfoximines with Diarylmethanes: A New Route to N-Alkylated Sulfoximines

Ying Cheng et al.

ORGANIC LETTERS (2014)

Add to Collection

Article Multidisciplinary Sciences

A Dual-Catalysis Approach to Enantioselective [2+2] Photocycloadditions Using Visible Light

Juana Du et al.

SCIENCE (2014)

Add to Collection

Article Chemistry, Organic

Recent progress in copper-catalyzed difunctionalization of unactivated carbon-carbon multiple bonds

Yohei Shimizu et al.

TETRAHEDRON LETTERS (2014)

Add to Collection

Article Chemistry, Applied

The Copper-Catalyzed Oxidative N-Acylation of Sulfoximines

Long Wang et al.

ADVANCED SYNTHESIS & CATALYSIS (2013)

Add to Collection

Article Chemistry, Multidisciplinary

Effective Synthesis of Chiral N-Fluoroaryl Aziridines through Enantioselective Aziridination of Alkenes with Fluoroaryl Azides

Li-Mei Jin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Add to Collection

Article Chemistry, Organic

Oxyarylation and Aminoarylation of Styrenes Using Photoredox Catalysis

Gabriela Fumagalli et al.

ORGANIC LETTERS (2013)

Add to Collection

Article Chemistry, Organic

Intermolecular Aminotrifluoromethylation of Alkenes by Visible-Light-Driven Photoredox Catalysis

Yusuke Yasu et al.

ORGANIC LETTERS (2013)

Add to Collection

Article Chemistry, Multidisciplinary

Synthesis of Enantiomerically Enriched Imidazolidin-2-Ones through Asymmetric Palladium-Catalyzed Alkene Carboamination Reactions

Brett A. Hopkins et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Add to Collection

Article Chemistry, Multidisciplinary

Copper-Catalyzed Enantioselective Intramolecular Alkene Amination/Intermolecular Heck-Type Coupling Cascade

Timothy W. Liwosz et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Add to Collection

Article Chemistry, Inorganic & Nuclear

Kinetic and Spectroscopic Studies of Aerobic Copper(II)-Catalyzed Methoxylation of Arylboronic Esters and Insights into Aryl Transmetalation to Copper(II)

Amanda E. King et al.

ORGANOMETALLICS (2012)

Add to Collection

Article Multidisciplinary Sciences

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

Todd K. Hyster et al.

SCIENCE (2012)

Add to Collection

Article Multidisciplinary Sciences

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

Baihua Ye et al.

SCIENCE (2012)

Add to Collection

Review Chemistry, Organic

Recent Developments in Palladium-Catalyzed Alkene Aminoarylation Reactions for the Synthesis of Nitrogen Heterocycles

Danielle M. Schultz et al.

SYNTHESIS-STUTTGART (2012)

Add to Collection

Review Chemistry, Multidisciplinary

Palladium(II)-Catalyzed Alkene Functionalization via Nucleopalladation: Stereochemical Pathways and Enantioselective Catalytic Applications

Richard I. McDonald et al.

CHEMICAL REVIEWS (2011)

Add to Collection

Article Chemistry, Multidisciplinary

A New Family of Cinchona-Derived Amino Phosphine Precatalysts: Application to the Highly Enantio- and Diastereoselective Silver-Catalyzed Isocyanoacetate Aldol Reaction

Filippo Sladojevich et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Add to Collection

Article Chemistry, Physical

Copper Catalyzed Atom Transfer Radical Addition (ATRA) and Cyclization (ATRC) Reactions in the Presence of Reducing Agents

William T. Eckenhoff et al.

CATALYSIS REVIEWS-SCIENCE AND ENGINEERING (2010)

Add to Collection

Review Chemistry, Multidisciplinary

Overview of the Mechanistic Work on the Concerted Metallation-Deprotonation Pathway

David Lapointe et al.

CHEMISTRY LETTERS (2010)

Add to Collection

Article Chemistry, Multidisciplinary

Asymmetric Palladium-Catalyzed Carboamination Reactions for the Synthesis of Enantiomerically Enriched 2-(Arylmethyl)- and 2-(Alkenylmethyl)pyrrolidines

Duy N. Mai et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Add to Collection

Article Multidisciplinary Sciences

Merging photoredox catalysis with organocatalysis: The direct asymmetric alkylation of aldehydes

David A. Nicewicz et al.

SCIENCE (2008)

Add to Collection

Article Chemistry, Multidisciplinary

Copper(II)-catalyzed enantioselective intramolecular carboamination of alkenes

Wei Zeng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Add to Collection

Article Chemistry, Multidisciplinary

Palladium-catalyzed benzene arylation: Incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design

Marc Lafrance et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Add to Collection

Article Chemistry, Organic

Carbodiazenylation of olefins by radical iodine transfer and addition to arenediazonium salts

Olga Blank et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2006)

Add to Collection

Article Chemistry, Multidisciplinary

Proton abstraction mechanism for the palladium-catalyzed intramolecular arylation

D García-Cuadrado et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Add to Collection

Article Chemistry, Multidisciplinary

Computational study of the mechanism of cyclometalation by palladium acetate

DL Davies et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Add to Collection

Review Chemistry, Multidisciplinary

Enantioselective radical processes

MP Sibi et al.

CHEMICAL REVIEWS (2003)

Add to Collection

Review Chemistry, Multidisciplinary

Atom transfer radical polymerization

K Matyjaszewski et al.

CHEMICAL REVIEWS (2001)

Add to Collection

A Counterion/Ligand-Tuned Chemo- and Enantioselective Copper- Catalyzed Intermolecular Radical 1,2-Carboamination of Alkenes

Related references

Export Citation

Share Paper