Journal
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Volume 88, Issue 1, Pages 1-10Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jaad.2022.04.068
Keywords
atypical melanocytic hyperplasia; atypical nevi; B-K mole syndrome; Bolognia sign; dermoscopy; dysplasia; dysplastic nevi; familial atypical multiple mole-melanoma syndrome; melanocytic nevi; mlanoma; MPATH-Dx; reflectance confocal microscopy; total body photography
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The diagnosis and management of dysplastic nevi have long been controversial in dermatology and dermatopathology fields, with diagnostic uncertainty and lack of standardized nomenclature causing confusion. In this CME review article, the historical context and key features for diagnosis, classification, and management of dysplastic nevi are summarized. The article also discusses the diagnostic utility of clinical criteria, dermoscopic features, histopathologic features, total body photography, and reflectance confocal microscopy. (J Am Acad Dermatol 2023;88:1-10.)
Since the late 1970s, the diagnosis and management of dysplastic nevi have been areas fraught with controversy in the fields of dermatology and dermatopathology. Diagnostic uncertainty and lack of standardized nomenclature continue to propagate confusion among clinicians, dermatopathologists, and patients. In part I of this CME review article, we summarize the historical context that gave rise to the debate surrounding dysplastic nevi and review key features for diagnosis, classification, and management, as well as epidemiology. We discuss essentials of clinical criteria, dermoscopic features, histopathologic features, and the diagnostic utility of total body photography and reflectance confocal microscopy in evaluating dysplastic nevi, with emphasis on information available since the last comprehensive review a decade ago. ( J Am Acad Dermatol 2023;88:1-10.)
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