Journal
JOURNAL OF SURGICAL ONCOLOGY
Volume 126, Issue 5, Pages 865-871Publisher
WILEY
DOI: 10.1002/jso.27060
Keywords
cancer management; gastric cancer; surgical oncology
Funding
- NIH
- NIH/NCI Cancer Center Support Grant [P30 CA008748]
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This article summarizes the important changes in gastric cancer management and the supporting data. These changes have been derived from randomized controlled trials, prospective databases, and in-depth analysis of individual patients.
As with every human malignancy, the diagnosis, staging, and treatment of patients with gastric cancer have undergone enormous evidence-based change over the last 50 years, largely as a result of increasingly rapid developments in technology and science. Some of the changes in clinical practice have derived from prospective randomized controlled trials (RCTs), whereas others have come from study of meticulously maintained prospective databases, which define the disease's natural history over time, and occasionally from in-depth analysis of a single patient with an unexpectedly good or poor outcome. Herein we summarize the more important changes in gastric cancer management and the data supporting those changes.
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