4.5 Editorial Material

Prologue: Evidence Informing the GRAPPA 2021 Treatment Recommendations, by Domain

Related references

Note: Only part of the references are listed.
Review Rheumatology

Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients with Psoriatic Arthritis: An Updated Review the 2021 GRAPPA Treatment Recommendations

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Summary: This study summarizes the efficacy and safety of advanced therapies for psoriatic arthritis in patients with related conditions, including Crohn's disease, ulcerative colitis, and noninfectious uveitis. The tumor necrosis factor inhibitor (TNFi) class appears to be effective and safe, while interleukin 12/23 inhibitors (IL-12/23i) show efficacy in Crohn's disease and ulcerative colitis. However, caution should be exercised when using interleukin 17 inhibitors (IL-17i) in patients with psoriatic arthritis at high risk of inflammatory bowel disease.

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Summary: This article summarizes existing evidence regarding pharmaceutical and nonpharmaceutical interventions for enthesitis in patients with psoriatic arthritis (PsA) to facilitate an evidence-based update of the Group for Research and Assessment in Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for PsA. The article found several classes of systemic conventional and advanced therapies and local measures were recommended for active enthesitis in patients with PsA.

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Summary: This literature review aimed to identify the most efficacious current interventions for dactylitis and provide up-to-date scientific evidence to support the 2021 GRAPPA recommendations on the management of psoriatic arthritis. The analysis of original articles revealed a lack of consensus regarding dactylitis assessment and the paucity of data concerning the effect of certain medications.

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