Quality evaluation of Atractylodis macrocephalae rhizoma through fingerprint qualitative analysis and quantitative analysis of multi-components by single marker

Article Chemistry, Multidisciplinary

Study on quality evaluation of garidi-5 by fingerprint combined with quantitative analysis of multi-components by single marker (QAMS)

Ling Gao

Summary: By utilizing High-Performance Liquid Chromatography-Ultraviolet method, this study established fingerprints of Garidi-5 preparations from different manufacturers, identified 11 key components, and compared the results of QAMS method with the standard curve method, ultimately achieving quality evaluation of different preparations.

CHEMICAL PAPERS (2022)

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Article Spectroscopy

Geographical origin traceability of traditional Chinese medicine Atractylodes macrocephala Koidz. by using multi-way fluorescence fingerprint and chemometric methods

Yue-Yue Chang et al.

Summary: A strategy using fluorescence fingerprint combined with chemometric methods was proposed to classify AM samples from different geographical origins, showing a high accuracy in sample classification.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

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Article Chemistry, Analytical

Entirely control the quality consistency of Rong'e Yishen oral liquid by both quantified profiling and quantitative analysis of multi-components by single marker method

Xiang Li et al.

Summary: The study combined quantified profiling and quantitative analysis of multi-components by single marker (QAMS) method to control the quality consistency of Rong'e Yishen oral liquid (REYS). The results showed that QAMS was effective in accurately controlling the quality of individual markers in the oral liquid, and the fingerprint evaluation demonstrated good quality consistency of REYS.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)

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Article Biochemistry & Molecular Biology

Quality Evaluation of Atractylodis Macrocephalae Rhizoma Based on Combinative Method of HPLC Fingerprint, Quantitative Analysis of Multi-Components and Chemical Pattern Recognition Analysis

Cheng Zheng et al.

Summary: This study developed a quality evaluation method for AMR based on HPLC fingerprint, HPLC quantification, and chemical pattern recognition analysis. Using cluster analysis and principal component analysis, the 27 batches of samples were categorized, and six differential components of AMR were identified through partial least-squares discriminant analysis. The method could be used for quality control and authentication of AMR.

MOLECULES (2021)

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Article Chemistry, Multidisciplinary

A four-dimensional separation approach by offline 2D-LC/IM-TOF-MS in combination with database-driven computational peak annotation facilitating the in-depth characterization of the multicomponents from Atractylodis Macrocephalae Rhizoma (Atractylodes macrocephala)

Yuexin Qian et al.

Summary: The complex chemical system of plant metabolites poses challenges for traditional liquid chromatography/mass spectrometry in clarifying chemical composition. An integrated approach with offline two-dimensional liquid chromatography/ion mobility quadrupole time-of-flight mass spectrometry has shown high orthogonality and improved identification of minor plant components in herbal medicine.

ARABIAN JOURNAL OF CHEMISTRY (2021)

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Review Integrative & Complementary Medicine

Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism

Yan Liu et al.

Summary: Mineral excipients play important roles in the pretreatment process of traditional Chinese medicines, but the lack of holistic understanding of their effects hinders their application and development. This review explores several mineral excipients, revealing their processing significance on traditional Chinese medicines through components, pharmacodynamics, and mechanism aspects.

CHINESE MEDICINE (2021)

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Review Chemistry, Medicinal

Atractylenolides (I, II, and III): a review of their pharmacology and pharmacokinetics

Mao Deng et al.

Summary: Atractylenolides derived from Atractylodes macrocephala Koidz have shown various pharmacological activities such as anti-cancer, anti-inflammatory, and neuroprotective effects. Further clinical studies are recommended to explore their therapeutic effects and potential side effects when combined with other drugs.

ARCHIVES OF PHARMACAL RESEARCH (2021)

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Article Chemistry, Analytical