Synthesis of Phenols from Aryl Ammonium Salts under Mild Conditions

A general method for the synthesis of phenols from electron-deficient aryl ammonium salts or heteroaryl ammonium salts under mild conditions was developed. Benzaldehyde oxime, acetohydroxamic acid, and hydroxylamine hydrochloride were investigated as hydroxide surrogates respectively. With these hydroxide surrogates, a series of phenols were prepared in yields of 20-98%.

Automated summary

A general method for synthesizing phenols from electron-deficient aryl ammonium salts or heteroaryl ammonium salts was developed using hydroxide surrogates such as benzaldehyde oxime, acetohydroxamic acid, and hydroxylamine hydrochloride, resulting in yields of 20-98%.