Related references
Note: Only part of the references are listed.The roles of kisspeptin and neurokinin B in GnRH pulse generation in humans, and their potential clinical application
Richard A. Anderson et al.
JOURNAL OF NEUROENDOCRINOLOGY (2022)
Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms
Elizabeth A. McCarthy et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)
Acute Effects of Kisspeptin Administration on Bone Metabolism in Healthy Men
Alexander N. Comninos et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)
Highlights of neuroanatomical discoveries of the mammalian gonadotropin-releasing hormone system
Rebecca E. Campbell et al.
JOURNAL OF NEUROENDOCRINOLOGY (2022)
Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour
Edouard G. Mills et al.
NATURE REVIEWS ENDOCRINOLOGY (2021)
Elinzanetant (NT-814), a Neurokinin 1,3 Receptor Antagonist, Reduces Estradiol and Progesterone in Healthy Women
Steve Pawsey et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)
The Relationship Between Bone and Reproductive Hormones Beyond Estrogens and Androgens
Edouard G. Mills et al.
ENDOCRINE REVIEWS (2021)
Differential Roles of Hypothalamic AVPV and Arcuate Kisspeptin Neurons in Estradiol Feedback Regulation of Female Reproduction
Luhong Wang et al.
NEUROENDOCRINOLOGY (2020)
Endometriosis
Krina T. Zondervan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas
James A. Simon et al.
OBSTETRICS AND GYNECOLOGY (2020)
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
Ali Abbara et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Effects of NT-814, a dual neurokinin 1 and 3 receptor antagonist, on vasomotor symptoms in postmenopausal women: a placebo-controlled, randomized trial
Mike Trower et al.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2020)
A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause
Graeme L. Fraser et al.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2020)
Potential roles for the kisspeptin/kisspeptin receptor system in implantation and placentation
Kai-Lun Hu et al.
HUMAN REPRODUCTION UPDATE (2019)
Management of Dopamine Agonist-Resistant Prolactinoma
Dominique Maiter
NEUROENDOCRINOLOGY (2019)
Kisspeptin as a Behavioral Hormone
Edouard G. A. Mills et al.
SEMINARS IN REPRODUCTIVE MEDICINE (2019)
Intrinsic links among sex, emotion, and reproduction
Lisa Yang et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Hypogonadotropic Hypogonadism in Men With Diabesity
Sandeep Dhindsa et al.
DIABETES CARE (2018)
The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans
Chioma Izzi-Engbeaya et al.
DIABETES OBESITY & METABOLISM (2018)
Kisspeptin and the control of emotions, mood and reproductive behaviour
Edouard G. A. Mills et al.
JOURNAL OF ENDOCRINOLOGY (2018)
Neurokinin 3 receptor antagonism rapidly improves vasomotor symptoms with sustained duration of action
Julia K. Prague et al.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2018)
A Neural Circuit Underlying the Generation of Hot Flushes
Stephanie L. Padilla et al.
CELL REPORTS (2018)
A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled trial
Ali Abbara et al.
HUMAN REPRODUCTION (2017)
Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline
Catherine M. Gordon et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial
Julia K. Prague et al.
LANCET (2017)
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist
H. S. Taylor et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo
Xavier d'Anglemont de Tassigny et al.
PLOS ONE (2017)
Hypothalamic-Pituitary-Ovarian Axis Reactivation by Kisspeptin-10 in Hyperprolactinemic Women With Chronic Amenorrhea
Robert P. Millar et al.
JOURNAL OF THE ENDOCRINE SOCIETY (2017)
Epidemiology of uterine fibroids: a systematic review
E. A. Stewart et al.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2017)
Ovarian hyperstimulation syndrome: review and new classification criteria for reporting in clinical trials
P. Humaidan et al.
HUMAN REPRODUCTION (2016)
Prevalence of infertility and help seeking among 15 000 women and men
J. Datta et al.
HUMAN REPRODUCTION (2016)
Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-D-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly Potent Testosterone-Suppressive Activity and Excellent Water Solubility
Naoki Nishizawa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Positive, But Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons
Sharon L. Dubois et al.
ENDOCRINOLOGY (2015)
Direct comparison of the effects of intravenous kisspeptin-10, kisspeptin-54 and GnRH on gonadotrophin secretion in healthy men
C. N. Jayasena et al.
HUMAN REPRODUCTION (2015)
Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy
Ali Abbara et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)
Menopause
Susan R. Davis et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Neurokinin B Administration Induces Hot Flushes in Women
Channa N. Jayasena et al.
SCIENTIFIC REPORTS (2015)
Acute and chronic effects of kisspeptin-54 administration on GH, prolactin and TSH secretion in healthy women
Channa N. Jayasena et al.
CLINICAL ENDOCRINOLOGY (2014)
Prolactin Regulates Kisspeptin Neurons in the Arcuate Nucleus to Suppress LH Secretion in Female Rats
Roberta Araujo-Lopes et al.
ENDOCRINOLOGY (2014)
Increasing LH Pulsatility in Women With Hypothalamic Amenorrhoea Using Intravenous Infusion of Kisspeptin-54
Channa N. Jayasena et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Sustained Exposure to the Investigational Kisspeptin Analog, TAK-448, Down-Regulates Testosterone into the Castration Range in Healthy Males and in Patients With Prostate Cancer: Results From Two Phase 1 Studies
David B. MacLean et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)
Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization
Channa N. Jayasena et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Endometriosis: pathogenesis and treatment
Paolo Vercellini et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Effects and Therapeutic Potentials of Kisspeptin Analogs: Regulation of the Hypothalamic-Pituitary-Gonadal Axis
Hisanori Matsui et al.
NEUROENDOCRINOLOGY (2014)
Pharmaceutical Options for Triggering of Final Oocyte Maturation in ART
Juan Carlos Castillo et al.
BIOMED RESEARCH INTERNATIONAL (2014)
A single injection of kisspeptin-54 temporarily increases luteinizing hormone pulsatility in healthy women
C. N. Jayasena et al.
CLINICAL ENDOCRINOLOGY (2013)
Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: Kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism
Jyothis T. George et al.
CLINICAL ENDOCRINOLOGY (2013)
Design, Synthesis, and Biological Evaluation of Novel Investigational Nonapeptide KISS1R Agonists with Testosterone-Suppressive Activity
Taiji Asami et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides
Taiji Asami et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Low Degree of Overlap Between Kisspeptin, Neurokinin B, and Dynorphin Immunoreactivities in the Infundibular Nucleus of Young Male Human Subjects Challenges the KNDy Neuron Concept
Erik Hrabovszky et al.
ENDOCRINOLOGY (2012)
Kisspeptin Administration to Women: A Window into Endogenous Kisspeptin Secretion and GnRH Responsiveness across the Menstrual Cycle
Yee-Ming Chan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Hyperprolactinemia-induced ovarian acyclicity is reversed by kisspeptin administration
Charlotte Sonigo et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Inactivating KISS1 Mutation and Hypogonadotropic Hypogonadism
A. Kemal Topaloglu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
LH and hCG Action on the Same Receptor Results in Quantitatively and Qualitatively Different Intracellular Signalling
Livio Casarini et al.
PLOS ONE (2012)
Role for kisspeptin/neurokinin B/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature
Melinda A. Mittelman-Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Evidence that the Arcuate Nucleus Is an Important Site of Progesterone Negative Feedback in the Ewe
Robert L. Goodman et al.
ENDOCRINOLOGY (2011)
Kisspeptin-10 Is a Potent Stimulator of LH and Increases Pulse Frequency in Men
J. T. George et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Diagnosis and Treatment of Hyperprolactinemia: An Endocrine Society Clinical Practice Guideline
Shlomo Melmed et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
The Effects of Kisspeptin-10 on Reproductive Hormone Release Show Sexual Dimorphism in Humans
Channa N. Jayasena et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
Update: Hypogonadotropic Hypogonadism in Type 2 Diabetes and Obesity
Paresh Dandona et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy
Gurjinder M. K. Nijher et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2010)
Twice-Weekly Administration of Kisspeptin-54 for 8 Weeks Stimulates Release of Reproductive Hormones in Women With Hypothalamic Amenorrhea
C. N. Jayasena et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2010)
Distribution and Postnatal Development of Gpr54 Gene Expression in Mouse Brain and Gonadotropin-Releasing Hormone Neurons
Allan E. Herbison et al.
ENDOCRINOLOGY (2010)
Neurokinin B Stimulates GnRH Release in the Male Monkey (Macaca mulatta) and Is Colocalized with Kisspeptin in the Arcuate Nucleus
Suresh Ramaswamy et al.
ENDOCRINOLOGY (2010)
Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion
Michael N. Lehman et al.
ENDOCRINOLOGY (2010)
The Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cell Population of the Arcuate Nucleus: Sex Differences and Effects of Prenatal Testosterone in Sheep
Guanliang Cheng et al.
ENDOCRINOLOGY (2010)
Hypothesis: Kisspeptin Mediates Male Hypogonadism in Obesity and Type 2 Diabetes
Jyothis T. George et al.
NEUROENDOCRINOLOGY (2010)
Functional Hypothalamic Amenorrhea
Catherine M. Gordon
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Kisspeptin Signaling in the Brain
Amy E. Oakley et al.
ENDOCRINE REVIEWS (2009)
Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women with Hypothalamic Amenorrhea, But Chronic Administration Causes Tachyphylaxis
Channa N. Jayasena et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain
J. Clarkson et al.
JOURNAL OF NEUROENDOCRINOLOGY (2009)
Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse
Victor M. Navarro et al.
JOURNAL OF NEUROSCIENCE (2009)
Menopause and the human hypothalamus: Evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback
Naomi E. Rance
PEPTIDES (2009)
The neuroanatomy of the kisspeptin system in the mammalian brain
Jens D. Mikkelsen et al.
PEPTIDES (2009)
Changes in Prodynorphin Gene Expression and Neuronal Morphology in the Hypothalamus of Postmenopausal Women
A. M. Rometo et al.
JOURNAL OF NEUROENDOCRINOLOGY (2008)
A GPR54-activating mutation in a patient with central precocious puberty
Milena Gurgel Teles et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin a and neurokinin B
Robert L. Goodman et al.
ENDOCRINOLOGY (2007)
Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice
Risto Lapatto et al.
ENDOCRINOLOGY (2007)
Kisspeptin-54 stimulates gonadotropin release most potently during the Preovulatory phase of the menstrual cycle in women
Waljit S. Dhillo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice
David R. Grattan et al.
ENDOCRINOLOGY (2007)
Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys
Adonna M. Rometo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene
Xavier d'Anglemont de Tassigny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Sexual differentiation of Kiss1 gene expression in the brain of the rat
Alexander S. Kauffman et al.
ENDOCRINOLOGY (2007)
Postnatal development of kisspeptin neurons in mouse hypothalamus; Sexual dimorphism and projections to gonadotropin-releasing hormone neurons
Jenny Clarkson et al.
ENDOCRINOLOGY (2006)
Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha
I. Franceschini et al.
NEUROSCIENCE LETTERS (2006)
Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats
S. Tovar et al.
ENDOCRINOLOGY (2006)
Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male rhesus monkey (Macaca mulatta):: A finding with therapeutic implications
SB Seminara et al.
ENDOCRINOLOGY (2006)
Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty
SK Han et al.
JOURNAL OF NEUROSCIENCE (2005)
Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males
WS Dhillo et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition
JM Castellano et al.
ENDOCRINOLOGY (2005)
Regulation of Kiss1 gene expression in the brain of the female mouse
JT Smith et al.
ENDOCRINOLOGY (2005)
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54
S Messager et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse
ML Gottsch et al.
ENDOCRINOLOGY (2004)
Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat
MS Irwig et al.
NEUROENDOCRINOLOGY (2004)
Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis
EL Thompson et al.
JOURNAL OF NEUROENDOCRINOLOGY (2004)
The GPR54 gene as a regulator of puberty
SB Seminara et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
N de Roux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Dramatic elevation of plasma metastin concentrations in human pregnancy: Metastin as a novel placenta-derived hormone in humans
Y Horikoshi et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
M Kotani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1
AI Muir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor
T Ohtaki et al.
NATURE (2001)
Share Paper
