4.2 Article

Pyogenic spondylitis caused by Streptococcus dysgalactiae subspecies equisimilis in a patient with nasopharyngeal cancer

Journal

JOURNAL OF INFECTION AND CHEMOTHERAPY
Volume 28, Issue 9, Pages 1332-1335

Publisher

ELSEVIER
DOI: 10.1016/j.jiac.2022.05.010

Keywords

Head and neck cancer; Catheter -related bloodstream infection; Pyogenic spondylitis; Streptococcus dysgalactiae subspecies equisimilis

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This article reports a case of a nasopharyngeal carcinoma patient who developed pyogenic spondylitis due to a catheter-related bloodstream infection after chemoradiotherapy. The infection was successfully treated with antibacterial therapy.
In the treatment of head and neck cancer, radiation therapy is an effective modality and is often used in routine clinical practice. Although rare, pyogenic spondylitis has been reported as a complication of radiation therapy. Here, we report a case of nasopharyngeal carcinoma resulting in pyogenic spondylitis from a catheter-related bloodstream infection after chemoradiotherapy. The initial symptoms were fever and posterior cervical pain. Streptococcus dysgalactiae subspecies equisimilis was detected in blood cultures. Magnetic resonance imaging showed abnormal enhancement of the C6 and C7 vertebrae and an anterior epidural abscess. The infection was successfully treated with antibacterial therapy.

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