Related references
Note: Only part of the references are listed.Cancer statistics, 2022
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2022)
TCF1 in T cell immunity: a broadened frontier
Xudong Zhao et al.
NATURE REVIEWS IMMUNOLOGY (2022)
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
Bola S. Hanna et al.
IMMUNITY (2021)
Tcf1 and Lef1 provide constant supervision to mature CD8+ T cell identity and function by organizing genomic architecture
Qiang Shan et al.
NATURE COMMUNICATIONS (2021)
Suppression of Wnt/β-catenin and RAS/ERK pathways provides a therapeutic strategy for gemcitabine-resistant pancreatic cancer
Won-Ji Ryu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis
Michael P. Kim et al.
CANCER DISCOVERY (2021)
WNT Ligand Dependencies in Pancreatic Cancer
Kristina Y. Aguilera et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages
Samantha B. Kemp et al.
LIFE SCIENCE ALLIANCE (2021)
N6-methyladenosine-Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression
Junge Deng et al.
CANCER RESEARCH (2021)
Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
Megan L. Burger et al.
CELL (2021)
TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer
Abu Osman et al.
NATURE IMMUNOLOGY (2021)
Therapeutic Potential of Targeting Stromal Crosstalk-Mediated Immune Suppression in Pancreatic Cancer
Wenting Du et al.
FRONTIERS IN ONCOLOGY (2021)
Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy
Jichang Han et al.
NATURE CANCER (2021)
KYA1797K down-regulates PD-L1 in colon cancer stem cells to block immune evasion by suppressing the β-catenin/STT3 signaling pathway
Zhiyan Ruan et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis
Yaqing Zhang et al.
CANCER DISCOVERY (2020)
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
Samarth Hegde et al.
CANCER CELL (2020)
Interleukin-17 promotes nitric oxide-dependent expression of PD-L1 in mesenchymal stem cells
Shijia Wang et al.
CELL AND BIOSCIENCE (2020)
Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer
Nina G. Steele et al.
NATURE CANCER (2020)
WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer
Lorenzo Castagnoli et al.
ONCOGENE (2019)
Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy
Qiang Zhang et al.
CANCER RESEARCH (2019)
WNT Signaling in Cancer Immunosurveillance
Lorenzo Galluzzi et al.
TRENDS IN CELL BIOLOGY (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
IL-17A secreted from lymphatic endothelial cells promotes tumorigenesis by upregulation of PD-L1 in hepatoma stem cells
Yuanyan Wei et al.
JOURNAL OF HEPATOLOGY (2019)
Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial
Robert P. Jones et al.
JAMA SURGERY (2019)
Epithelial-Stromal Interactions in Pancreatic Cancer
Yaqing Zhang et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)
WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers
Jason J. Luke et al.
CLINICAL CANCER RESEARCH (2019)
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy
Imran Siddiqui et al.
IMMUNITY (2019)
Wnt signalling: conquering complexity
Katrin E. Wiese et al.
DEVELOPMENT (2018)
Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells
Yu Zhang et al.
GASTROENTEROLOGY (2018)
Integrating single-cell transcriptomic data across different conditions, technologies, and species
Andrew Butler et al.
NATURE BIOTECHNOLOGY (2018)
Understanding the tumor immune microenvironment (TIME) for effective therapy
Mikhail Binnewies et al.
NATURE MEDICINE (2018)
Targeting Wnt/β-Catenin Signaling for Cancer Immunotheraoy
Bojun Wang et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
Moshe Sade-Feldman et al.
CELL (2018)
Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy
Babita Madan et al.
BONE RESEARCH (2018)
Immunotherapy and Prevention of Pancreatic Cancer
Alexander H. Morrison et al.
TRENDS IN CANCER (2018)
Impact of oncogenic pathways on evasion of antitumour immune responses
Stefani Spranger et al.
NATURE REVIEWS CANCER (2018)
Patterns, Timing, and Predictors of Recurrence Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma
Vincent P. Groot et al.
ANNALS OF SURGERY (2018)
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
Yaqing Zhang et al.
GUT (2017)
Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Zachary Steinhart et al.
NATURE MEDICINE (2017)
Inflammatory cytokines IL-17 and TNF-α up-regulate PD-L1 expression in human prostate and colon cancer cells
Xun Wang et al.
IMMUNOLOGY LETTERS (2017)
Crosstalk between Regulatory T Cells and Tumor-Associated Dendritic Cells Negates Anti-tumor Immunity in Pancreatic Cancer
Jung-Eun Jang et al.
CELL REPORTS (2017)
WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
Marcus M. Fischer et al.
SCIENCE ADVANCES (2017)
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
Roel Nusse et al.
CELL (2017)
The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma
Priya Pai et al.
MOLECULAR ONCOLOGY (2016)
Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity
Yuan Hong et al.
ONCOIMMUNOLOGY (2016)
γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation
Donnele Daley et al.
CELL (2016)
Genetics and biology of pancreatic ductal adenocarcinoma
Haoqiang Ying et al.
GENES & DEVELOPMENT (2016)
IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma
Kristen B. Long et al.
CANCER DISCOVERY (2016)
Activation of WNT/β- Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61
Makoto Sano et al.
NEOPLASIA (2016)
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
Rebecca A. Evans et al.
JCI INSIGHT (2016)
Organoid Models of Human and Mouse Ductal Pancreatic Cancer
Sylvia F. Boj et al.
CELL (2015)
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
Stefani Spranger et al.
NATURE (2015)
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow
Qi Yang et al.
NATURE IMMUNOLOGY (2015)
A new paradigm for tumor immune escape: β-catenin-driven immune exclusion
Stefani Spranger et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2015)
Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia
Florencia McAllister et al.
CANCER CELL (2014)
Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity
Ingunn M. Stromnes et al.
GUT (2014)
All-trans Retinoic Acid Induces Arginase-1 and Inducible Nitric Oxide Synthase-Producing Dendritic Cells with T Cell Inhibitory Function
Sumantha Bhatt et al.
JOURNAL OF IMMUNOLOGY (2014)
Can we safely target the WNT pathway?
Michael Kahn
NATURE REVIEWS DRUG DISCOVERY (2014)
CD4+ T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice
Yaqing Zhang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Yaqing Zhang et al.
CANCER RESEARCH (2013)
Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
Xiaomo Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
Jun Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Generation of CD4CreERT2 Transgenic Mice to Study Development of Peripheral CD4-T-Cells
Katayoun Aghajani et al.
GENESIS (2012)
MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells
Atsuo Ochi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Immune Suppression and Resistance Mediated by Constitutive Activation of Wnt/β-Catenin Signaling in Human Melanoma Cells
Tomonori Yaguchi et al.
JOURNAL OF IMMUNOLOGY (2012)
Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Wnt Signaling in Mammalian Development: Lessons from Mouse Genetics
Jianbo Wang et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
A human memory T cell subset with stem cell-like properties
Luca Gattinoni et al.
NATURE MEDICINE (2011)
Alternatively Activated Macrophage Possess Antitumor Cytotoxicity That Is Induced by IL-4 and Mediated by Arginase-1
Julia I. Ellyard et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory
Gregoire Jeannet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
John P. Morris et al.
NATURE REVIEWS CANCER (2010)
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
De La O. Jean-Paul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
Carolyn E. Clark et al.
CANCER RESEARCH (2007)
Hedgehog/Ras interactions regulate early stages of pancreatic cancer
Marina Pasca di Magliano et al.
GENES & DEVELOPMENT (2006)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
LP Chen
NATURE REVIEWS IMMUNOLOGY (2004)
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
DM Berman et al.
NATURE (2003)
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
SP Thayer et al.
NATURE (2003)
T-cell development and the CD4-CD8 lineage decision
RN Germain
NATURE REVIEWS IMMUNOLOGY (2002)
Share Paper
