Related references
Note: Only part of the references are listed.Disorder-to-order transition of the amyloid-/3 peptide upon lipid binding
Hebah Fatafta et al.
BIOPHYSICAL CHEMISTRY (2022)
Effect of Cholesterol Molecules on Aβ1-42 Wild-Type and Mutants Trimers
Trung Hai Nguyen et al.
MOLECULES (2022)
Cholesterol in Membranes Facilitates Aggregation of Amyloid β Protein at Physiologically Relevant Concentrations
Siddhartha Banerjee et al.
ACS CHEMICAL NEUROSCIENCE (2021)
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis
Phuong H. Nguyen et al.
CHEMICAL REVIEWS (2021)
Met35 Oxidation Hinders Aβ25-35 Peptide Aggregation within the Dimyristoylphosphatidylcholine Bilayer
Elias Khayat et al.
ACS CHEMICAL NEUROSCIENCE (2021)
Amyloid-β peptide dimers undergo a random coil to β-sheet transition in the aqueous phase but not at the neuronal membrane
Hebah Fatafta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Role of Oxidized Gly25, Gly29, and Gly33 Residues on the Interactions of Aβ1-42 with Lipid Membranes
Hebah Fatafta et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Interaction of A beta 42 with Membranes Triggers the Self-Assembly into Oligomers
Siddhartha Banerjee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Three Popular Force Fields Predict Consensus Mechanism of Amyloid β Peptide Binding to the Dimyristoylgylcerophosphocholine Bilayer
Christopher Lockhart et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2020)
Phosphorylation Promotes Aβ25-35 Peptide Aggregation within the DMPC Bilayer
Elias Khayat et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Nanoscale Interplay of Membrane Composition and Amyloid Self-Assembly
Sneha Menon et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2020)
Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage
Sonia Ciudad et al.
NATURE COMMUNICATIONS (2020)
Lipid-protein interactions in amyloid formation
Emma Sparr et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2019)
A vicious cycle of β amyloid-dependent neuronal hyperactivation
Benedikt Zott et al.
SCIENCE (2019)
Do Cholesterol and Sphingomyelin Change the Mechanism of Aβ25-35 Peptide Binding to Zwitterionic Bilayer?
Amy K. Smith et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
The interactions of an Aβ protofibril with a cholesterol-enriched membrane and involvement of neuroprotective carbazolium-based substances
Hedayat Karimi et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)
Pathways of amyloid-beta absorption and aggregation in a membranous environment
Abhilash Sahoo et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)
Physiologically-relevant levels of sphingomyelin, but not GM1, induces a β-sheet-rich structure in the amyloid-β(1-42) monomer
Michael C. Owen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
Binding of Cytotoxic Aβ25-35 Peptide to the Dimyristoylphosphatidylcholine Lipid Bilayer
Amy K. Smith et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2018)
Looking at the Disordered Proteins through the Computational Microscope
Payel Das et al.
ACS CENTRAL SCIENCE (2018)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
Cholesterol Changes the Mechanisms of Aβ Peptide Binding to the DMPC Bilayer
Christopher Lockhart et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2017)
Self-Assembly Pathways of β-Sheet-Rich Amyloid-β(1-40) Dimers: Markov State Model Analysis on Millisecond Hybrid-Resolution Simulations
Yang Cao et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2017)
The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner
Alex L. Lai et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
Aggregation of Aβ(17-36) in the Presence of Naturally Occurring Phenolic Inhibitors Using Coarse-Grained Simulations
Yiming Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
Inclusion of lipopeptides into the DMPC lipid bilayers prevents Aβ peptide insertion
Niyati Parikh et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2017)
Alzheimer's Disease and the Amyloid-β Peptide
M. Paul Murphy et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Lipid membranes catalyse the fibril formation of the amyloid-β (1-42) peptide through lipid-fibril interactions that reinforce secondary pathways
David J. Lindberg et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)
Influence of sequence and lipid type on membrane perturbation by human and rat amyloid β-peptide (1-42)
Anne M. Brown et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)
Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity
Andreas Mueller-Schiffmann et al.
BRAIN (2016)
CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field
Jumin Lee et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2016)
The Alzheimer's disease Aβ peptide binds to the anionic DMPS lipid bilayer
Christopher Lockhart et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)
Molecular dynamics simulations of biological membranes and membrane proteins using enhanced conformational sampling algorithms
Takaharu Mori et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)
Coarse-Grained Protein Models and Their Applications
Sebastian Kmiecik et al.
CHEMICAL REVIEWS (2016)
Does Replica Exchange with Solute Tempering Efficiently Sample Aβ Peptide Conformational Ensembles?
Amy K. Smith et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2016)
Alzheimer's disease: An overview of amyloid beta dependent pathogenesis and its therapeutic implications along with in silico approaches emphasizing the role of natural products
Manika Awasthi et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2016)
Biophysical insights into the membrane interaction of the core amyloid-forming Aβ40 fragment K16-K28 and its role in the pathogenesis of Alzheimer's disease
Swapna Bera et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)
Drug development in Alzheimer's disease: the path to 2025
Jeffrey Cummings et al.
ALZHEIMERS RESEARCH & THERAPY (2016)
Alzheimer's Association Report 2015 Alzheimer's disease facts and figures
ALZHEIMERS & DEMENTIA (2015)
Calcium Enhances Binding of Aβ Monomer to DMPC Lipid Bilayer
Christopher Lockhart et al.
BIOPHYSICAL JOURNAL (2015)
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies
Jessica Nasica-Labouze et al.
CHEMICAL REVIEWS (2015)
Long-Time-Step Molecular Dynamics through Hydrogen Mass Repartitioning
Chad W. Hopkins et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease
Sagar H. Barage et al.
NEUROPEPTIDES (2015)
Understanding Amyloid Fibril Nucleation and Aβ Oligomer/Drug Interactions from Computer Simulations
Phuong Nguyent et al.
ACCOUNTS OF CHEMICAL RESEARCH (2014)
Effect of the English Familial Disease Mutation (H6R) on the Monomers and Dimers of Aβ40 and Aβ42
Man Hoang Viet et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Binding of Aβ peptide creates lipid density depression in DMPC bilayer
Christopher Lockhart et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
Alzheimer's Aβ10-40 Peptide Binds and Penetrates DMPC Bilayer: An Isobaric-Isothermal Replica Exchange Molecular Dynamics Study
Christopher Lockhart et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2014)
How the amyloid-β peptide and membranes affect each other: An extensive simulation study
Chetan Poojari et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Embedding Aβ42 in Heterogeneous Membranes Depends on Cholesterol Asymmetries
Nicoletta Liguori et al.
BIOPHYSICAL JOURNAL (2013)
PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
Daniel R. Roe et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Deciphering the mechanism underlying late-onset Alzheimer disease
Dimitrije Krstic et al.
NATURE REVIEWS NEUROLOGY (2013)
Stability of Transmembrane Amyloid β-Peptide and Membrane Integrity Tested by Molecular Modeling of Site-Specific Aβ42 Mutations
Chetan Poojari et al.
PLOS ONE (2013)
Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-D-Enantiomer of Alzheimer's β-Amyloid Peptide: Relevance to the Ion Channel Mechanism of AD Pathology
Laura Connelly et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
H++3.0: automating pK prediction and the preparation of biomolecular structures for atomistic molecular modeling and simulations
Ramu Anandakrishnan et al.
NUCLEIC ACIDS RESEARCH (2012)
Membrane and surface interactions of Alzheimer's Aβ peptide - insights into the mechanism of cytotoxicity
Thomas L. Williams et al.
FEBS JOURNAL (2011)
Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes
Justin A. Lemkul et al.
PROTEIN SCIENCE (2011)
Transmembrane Structures for Alzheimer's Aβ1-42 Oligomers
Birgit Strodel et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
CHARMM-GUI Membrane Builder for Mixed Bilayers and Its Application to Yeast Membranes
Sunhwan Jo et al.
BIOPHYSICAL JOURNAL (2009)
Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters
Maho Utsumi et al.
GLYCOCONJUGATE JOURNAL (2009)
Amyloid-β Membrane Binding and Permeabilization are Distinct Processes Influenced Separately by Membrane Charge and Fluidity
Pamela T. Wong et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
EVOLUTION OF Aβ42 AND Aβ40 LEVELS AND Aβ42/Aβ40 RATIO IN PLASMA DURING PROGRESSION OF ALZHEIMER'S DISEASE: A MULTICENTER ASSESSMENT
K. Blennow et al.
JOURNAL OF NUTRITION HEALTH & AGING (2009)
The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity
Asad Jan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
P-LINCS: A parallel linear constraint solver for molecular simulation
Berk Hess
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Membrane lipids: where they are and how they behave
Gerrit van Meer et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide
Eva Y. Chi et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Misfolding of amyloidogenic proteins at membrane surfaces:: The impact of macromolecular crowding
Marcus Bokvist et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Aβ ion channels.: Prospects for treating Alzheimer's disease with Aβ channel blockers
Nelson Arispe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
The α-to-β conformational transition of Alzheimer's Aβ-(1-42) peptide in aqueous media is reversible:: A step by step conformational analysis suggests the location of β conformation seeding
S Tomaselli et al.
CHEMBIOCHEM (2006)
GROMACS: Fast, flexible, and free
D Van der Spoel et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
The Amber biomolecular simulation programs
DA Case et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
H++:: a server for estimating pKas and adding missing hydrogens to macromolecules
JC Gordon et al.
NUCLEIC ACIDS RESEARCH (2005)
Two types of Alzheimer's β-amyloid (1-40) peptide membrane interactions:: Aggregation preventing transmembrane anchoring Versus accelerated surface fibril formation
M Bokvist et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Kinetics of adsorption of β-amyloid peptide Aβ(1-40) to lipid bilayers
JJ Kremer et al.
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS (2003)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Amyloid β protein forms ion channels:: implications for Alzheimer's disease pathophysiology
H Lin et al.
FASEB JOURNAL (2001)