4.6 Article

Numerical investigation of flexible Purcell-like integrated microfluidic pumps

Journal

JOURNAL OF APPLIED PHYSICS
Volume 132, Issue 16, Pages -

Publisher

AIP Publishing
DOI: 10.1063/5.0109263

Keywords

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Funding

  1. EPSRC Centre for Doctoral Training in Metamaterials [EP/L015331/1]
  2. European Union's HORIZON2020 Research and Innovation Program [665440, 801374]
  3. MRC [MCPC17189]
  4. Royal Society Research Grant [RG180007]
  5. Wellcome Trust Strategic Seed Corn Fund [WT097835/Z/11/Z]
  6. Marie Sklodowska-Curie Grant [H2020-MSCA-ITN-2015-675752]
  7. Biotechnology and Biological Sciences Research Council [BB/V008201/1]

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Integrating miniature pumps within microfluidic devices is crucial for advancing point-of-care diagnostics. This study simulates and evaluates the performance of an elastic-magnetic integrated microfluidic pump, revealing the correlation between the emergence of flow behavior and variables such as frequency and proximity, and providing important insights for the design and optimization of the pump.
Integrating miniature pumps within microfluidic devices is crucial for advancing point-of-care diagnostics. Understanding the emergence of flow from novel integrated pumping systems is the first step in their successful implementation. A Purcell-like elasto-magnetic integrated microfluidic pump has been simulated in COMSOL Multiphysics and its performance has been investigated and evaluated. An elastic, cilia-like element contains an embedded magnet, which allows for actuation via a weak, uniaxial, sinusoidally oscillating, external magnetic field. Pumping performance is correlated against a number of variables, such as the frequency of the driving field and the proximity of the pump to the channel walls, in order to understand the emergence of the pumping behavior. Crucially, these simulations capture many of the trends observed experimentally and shed light on the key interactions. The proximity of the channel walls in the in-plane direction strongly determines the direction of net fluid flow. This characterization has important implications for the design and optimization of this pump in practical applications. (c) 2022 Author(s).

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