Sodium Alginate-Natural Microencapsulation Material of Polymeric Microparticles

From the multitude of materials currently available on the market that can be used in the development of microparticles, sodium alginate has become one of the most studied natural anionic polymers that can be included in controlled-release pharmaceutical systems alongside other polymers due to its low cost, low toxicity, biocompatibility, biodegradability and gelatinous die-forming capacity in the presence of Ca2+ ions. In this review, we have shown that through coacervation, the particulate systems for the dispensing of drugs consisting of natural polymers are nontoxic, allowing the repeated administration of medicinal substances and the protection of better the medicinal substances from degradation, which can increase the capture capacity of the drug and extend its release from the pharmaceutical form.

Automated summary

Sodium alginate is a natural polymer that has been extensively studied for its low cost, low toxicity, biocompatibility, biodegradability, and gel-forming capacity in the presence of Ca2+ ions. It can be included in controlled-release pharmaceutical systems to enhance drug capture capacity and extend drug release from the pharmaceutical form.