Mechanochemical Transformations of Polysaccharides: A Systematic Review

Taking into consideration the items of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), this study reviews application of mechanochemical approaches to the modification of polysaccharides. The ability to avoid toxic solvents, initiators, or catalysts during processes is an important characteristic of the considered approach and is in line with current trends in the world. The mechanisms of chemical transformations in solid reactive systems during mechanical activation, the structure and physicochemical properties of the obtained products, their ability to dissolve and swell in different media, to form films and fibers, to self-organize in solution and stabilize nanodispersed inorganic particles and biologically active substances are considered using a number of polysaccharides and their derivatives as examples.

Automated summary

This study reviews the application of mechanochemical approaches to modify polysaccharides. The considered approach is characterized by the ability to avoid toxic solvents, initiators, or catalysts, aligning with current global trends. Examples using various polysaccharides and their derivatives are used to analyze the mechanisms of chemical transformations, the structure and properties of the products, their solubility and swelling in different media, and their ability to self-organize and stabilize nanodispersed inorganic particles and biologically active substances.