Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 221, Issue -, Pages 1251-1258Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2022.08.208
Keywords
Phenamacril; Ethyl cellulose; Nanocapsules; Fusarium head blight; Fungicide
Funding
- National Key Research and Development Program of China [2021YFA0716700]
- Central Public-interest Sci-entific Institution Basal Research Fund [BSRF202113]
- Agricultural Science and Technology Innovation Program
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This study developed an ethyl cellulose-based phenamacril nano-delivery system to improve the control of fusarium head blight in wheat. The synthesized nanocapsules showed excellent storage stability and wettability on crop leaves, and demonstrated significantly improved biological activity against Fusarium graminearum.
Fungicide-resistant Fusarium has become a threaten to wheat production. Novel fungicide formulations can improve the efficacy of active ingredient and minimize the emergence of resistance. Encapsulation of fungicides in biodegradable carriers, especially, in polysaccharide, is a feasible approach to develop environment-friendly and efficient formulation. This study focused on the synthesis of ethyl cellulose-based phenamacril nano-delivery system by combining emulsion-solvent evaporation and high-pressure homogenization technology to improve the control of fusarium head blight in wheat. Emulsifier 125 and Tersperse 2500 were screened from eleven commonly used surfactants. Emulsifier 125 and Tersperse 2500 in a ratio of 2:1 and phenamacril nanocapsules with the mean particle size of 152.5 & PLUSMN; 1.3 nm were prepared. These showed excellent storage stability and wettability on crop leaves. A bioassay comparing the nanocapsules with a commercial preparation against Fusarium graminearum showed significantly improved biological activity. This formulation could be used to effectively not only to control fusarium head blight but also delay the occurrence of resistance.
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