4.2 Article

Deep Brain Stimulation in a Patient with Parkinson's Disease and Cortical Superficial Siderosis

Journal

INTERNAL MEDICINE
Volume 61, Issue 21, Pages 3277-3279

Publisher

JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.9253-21

Keywords

intracerebral hemorrhage; cortical superficial siderosis; cerebral amyloid angiopathy; Parkinson's disease; deep brain stimulation

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This case report describes incidental microhemorrhages detected on MRI one week after deep brain stimulation surgery in a 68-year-old male with cSS and PD. cSS is considered a significant risk factor for CAA and future bleeding. Therefore, caution should be exercised when performing DBS surgery in patients with PD and CAA.
Cortical superficial siderosis (cSS) is a rare condition that is regarded as a potential magnetic resonance marker of cerebral amyloid angiopathy (CAA). We describe the case of a 68-year-old man with cSS and Parkinson's disease (PD) who subsequently exhibited incidental microhemorrhages, which were only detected on magnetic resonance imaging (MRI), at one week after deep brain stimulation (DBS) surgery. cSS is now considered to be a significant risk factor for CAA and future bleeding. Therefore, because DBS surgery is in-vasive and may increase the risk of intracerebral hemorrhage, the procedure should be performed carefully when managing patients with PD and CAA.

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