Trends in Clostridioides difficile infection rates in Canadian hospitals during the coronavirus disease 2019 (COVID-19) pandemic

Article Biochemistry & Molecular Biology

Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

Irina Leonardi et al.

Summary: The spatial organization of gut mycobiota is associated with intestinal epithelial function, host-protective immunity, and mouse behavior.

CELL (2022)

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Letter Public, Environmental & Occupational Health

The other 'C': Hospital-acquired Clostridioides difficile infection during the coronavirus disease 2019 (COVID-19) pandemic

Karl Hazel et al.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2022)

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Article Immunology

Characterization of Healthcare-Associated and Community-Associated Clostridioides difficile Infections among Adults, Canada, 2015-2019

Tim Du et al.

Summary: We investigated the epidemiology and molecular characteristics of healthcare-associated and community-associated Clostridioides difficile infection (CDI) in adult patients in Canadian hospitals. Our study found higher mortality rate associated with healthcare-associated CDI, and a decrease in both healthcare-associated and community-associated CDI rates from 2015 to 2019. Certain ribotypes were more commonly associated with CDI-related deaths.

EMERGING INFECTIOUS DISEASES (2022)

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Article Public, Environmental & Occupational Health

Impact of the coronavirus disease 2019 (COVID-19) pandemic on nosocomial Clostridioides difficile infection

Manuel Ponce-Alonso et al.

Summary: During the COVID-19 pandemic, there was a significant reduction in the incidence density of healthcare-facility-associated Clostridioides difficile infection (CDI), while antibiotic consumption slightly increased. The importance of reducing nosocomial transmission by healthcare workers and asymptomatic colonized patients, reinforcing cleaning procedures, and reducing patient mobility in the epidemiological control of CDI is highlighted.

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2021)

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Letter Public, Environmental & Occupational Health