4.7 Article

Human exposure to polybrominated diphenyl ethers (PBDEs) through the diet: An update of the scientific literature

Journal

FOOD AND CHEMICAL TOXICOLOGY
Volume 167, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2022.113322

Keywords

Polybrominated diphenyl ethers (PBDEs); Congeners; Food; Dietary exposure; Human health risks

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Polybrominated diphenyl ethers (PBDEs) are a type of brominated flame-retardants (BFRs) that are mainly introduced to the human body through dietary intake. This review discusses recent studies conducted from 2012 to 2022, which show a general trend of decreasing levels of PBDEs in food and consequently, a decrease in dietary intake. The lack of tolerable daily intakes of PBDEs remains a challenge for assessing the human health risks associated with these compounds.
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame-retardants (BFRs). As for other persistent organic pollutants, dietary intake (followed by dust inhalation) is the main route of human exposure to PBDEs. In 2012, we reviewed the scientific literature on the concentrations of PBDEs in foodstuffs and their dietary exposure. The current review is aimed at updating the results of recent studies (2012-2022) focused on determining the levels of PBDEs in food samples, as well as the dietary intake of these compounds. We have revised studies conducted over the world. The current information on the concentrations of PBDEs in food and their dietary intake is now much more notable than that available in our previous review, being China the country contributing with the highest number of studies. Because of the important differences in materials and methods used in the available studies, the comparison of results is certainly complicated. However, there seems to be a general trend towards a decrease in the levels of PBDEs in foods, and consequently, in the dietary intake of these contaminants. The lack of tolerable daily intakes of PBDEs is an issue that needs to be solved for assessing human health risks of these BFRs.

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