Journal
FITOTERAPIA
Volume 161, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.fitote.2022.105244
Keywords
Clinopodium polycephalum; Abietane diterpenoids; Triterpenoids; Anti-inflammatory activity
Categories
Funding
- National Natural Science Foundation of China [81573694]
- Science Foundation of the Educational Department of Liaoning Province [LJKZ0920]
- Liaoning BaiQianWan Talents Program in 2018
Ask authors/readers for more resources
Two previously undescribed diterpenes and one curious triterpenoid were isolated from Chnopodium polycephalum, a medicinal plant in China. Their structures were determined using various analytical techniques. These compounds showed inhibitory effects on NO production in cells without affecting cell viability.
Two previously undescribed diterpenes (1 and 2), as well as one curious triterpenoid were isolated from Chnopodium polycephalum, a medicinal plant distributed in southwestern and eastern China. Their structures were elucidated using MS analyses, UV spectrum, and extensive 2D-homo and hetemnuclear NMR data interpretations. Among them, 1 had an unusual skeletal characteristic produced by a rare methyl migration pathway. All monomer compounds exhibited inhibitory effects on NO production in LPS-induced RAW 264.7 cells without affecting cell viabilities, which were comparable to that of positive control.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available