Related references
Note: Only part of the references are listed.Cotargeting of Bcl-2 and Mcl-1 shows promising antileukemic activity against AML cells including those with acquired cytarabine resistance
Fangbing Liu et al.
EXPERIMENTAL HEMATOLOGY (2022)
SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets
Shuyu Zheng et al.
GENOMICS PROTEOMICS & BIOINFORMATICS (2022)
Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia
Alexander C. Lewis et al.
BLOOD (2022)
Acute myeloid leukemia: current progress and future directions
Hagop Kantarjian et al.
BLOOD CANCER JOURNAL (2021)
The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy
Megan Sheridan et al.
CANCERS (2021)
Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia
Fang-jiao Zhou et al.
JOURNAL OF CANCER (2021)
The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia
Charyguly Annageldiyev et al.
HAEMATOLOGICA (2020)
Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia
Jennifer M. Pearson et al.
MOLECULAR CANCER RESEARCH (2020)
Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
C. D. DiNardo et al.
BLOOD (2020)
Venetoclax plus LDAC for newly diagnosed AML ineligible for intensive chemotherapy: a phase 3 randomized placebo-controlled trial
Andrew H. Wei et al.
BLOOD (2020)
The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia
Charyguly Annageldiyev et al.
FRONTIERS IN ONCOLOGY (2020)
The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review
Kai Liu et al.
CANCER CELL INTERNATIONAL (2020)
Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma
Jeremy J. P. Shaw et al.
MOLECULAR CANCER THERAPEUTICS (2020)
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Ali Alhoshani et al.
ONCOTARGETS AND THERAPY (2020)
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells
Li-Pin Kao et al.
JOURNAL OF LIPID RESEARCH (2019)
Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia
Courtney D. DiNardo et al.
BLOOD (2019)
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia
Brian M. Barth et al.
BLOOD ADVANCES (2019)
Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo
Nicole D. Vincelette et al.
SCIENTIFIC REPORTS (2019)
Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients
Sharda Anroedh et al.
JOURNAL OF LIPID RESEARCH (2018)
The ceramide ratio: a predictor of cardiometabolic risk
Trevor S. Tippetts et al.
JOURNAL OF LIPID RESEARCH (2018)
Pathways and mechanisms of venetoclax resistance
Prithviraj Bose et al.
LEUKEMIA & LYMPHOMA (2017)
Lipidomic approach for stratification of acute myeloid leukemia patients
Adam Stefanko et al.
PLOS ONE (2017)
Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma
Zheng Wang et al.
ONCOTARGET (2017)
Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL
Kallesh D. Jayappa et al.
BLOOD ADVANCES (2017)
Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML
Mohammed Dany et al.
BLOOD (2016)
Ceramide synthases in biomedical research
Francesca Cingolani et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2016)
Genomic Classification and Prognosis in Acute Myeloid Leukemia
Elli Papaemmanuil et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
CHK1 as a therapeutic target to bypass chemoresistance in AML
Laure David et al.
SCIENCE SIGNALING (2016)
Acute myeloid leukemia: a comprehensive review and 2016 update
I. De Kouchkovsky et al.
BLOOD CANCER JOURNAL (2016)
CHK1 as a therapeutic target to bypass chemoresistance in AML
Laure David et al.
SCIENCE SIGNALING (2016)
Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis
Johnny Stiban et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic
Mark Kester et al.
BIOLOGICAL CHEMISTRY (2015)
Cancer Statistics, 2015
Rebecca L. Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2015)
Roles of Chk1 in cell biology and cancer therapy
Youwei Zhang et al.
INTERNATIONAL JOURNAL OF CANCER (2014)
Ceramide-orchestrated signalling in cancer cells
Samy A. F. Morad et al.
NATURE REVIEWS CANCER (2013)
Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth
Daniela Hartmann et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)
Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia
Jay P. Patel et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia
Xin Liu et al.
BLOOD (2010)
Patterns of leukemia incidence in the United States by subtype and demographic characteristics, 1997-2002
Jennifer F. Yamamoto et al.
CANCER CAUSES & CONTROL (2008)
Sphingolipid players in the leukemia arena
Clara Ricci et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained
D. P. Steensma et al.
LEUKEMIA (2006)
Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial
D Sampath et al.
BLOOD (2006)
Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma
TC Stover et al.
CLINICAL CANCER RESEARCH (2005)