Journal
EXPERT REVIEWS IN MOLECULAR MEDICINE
Volume 24, Issue -, Pages -Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/erm.2022.33
Keywords
Animal model; antioxidant; Cassia tora Linn; disease; preclinical
Funding
- Korea Innovation Foundation - Korean government (Ministry of Science and ICT) through a science and technology project [2021-DD-UP-0380]
- National Research Foundation of Korea (NRF) - Ministry of Science and ICT [2022R1A5A2029546, 2022R1A5A8033794]
- National Research Foundation of Korea [2022R1A5A2029546] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
The global aging population is increasing, posing a major risk factor for age-related diseases. Cassia tora Linn. has pharmacological activities that make it useful for anti-bacteria, anti-hyperlipidemia and anti-obesity purposes. However, clinical trials have not been conducted yet, so the current preclinical activities for aging-related disease models need to be understood and discussed.
Globally, an aging population is increasing, and aging is a natural physiological process and a major risk factor for all age-related diseases. It seriously threatens personal health and imposes a great economic burden. Therefore, there is a growing scientific interest in strategies for well-aging with prevention and treatment of age-related diseases. The seed, root, stem or leaves of Cassia tora Linn. are useful for anti-bacteria, anti-hyperlipidemia and anti-obesity due to its pharmacological activities such as anti-inflammation and anti-oxidant both in vitro and in vivo. Nevertheless, no clinical trials have been attempted so far, therefore here we would like to understand the current preclinical activities for aging-related disease models including cataract, metabolic dysfunction and neurodegeneration, then discuss their preparation for clinical trials and perspectives.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available