Related references
Note: Only part of the references are listed.Bioengineered models of Parkinson's disease using patient-derived dopaminergic neurons exhibit distinct biological profiles in a 3D microenvironment
Nicholas J. Fiore et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2022)
Molecular foundations of prion strain diversity
Manfredi Carta et al.
CURRENT OPINION IN NEUROBIOLOGY (2022)
Primary glia cells from bank vole propagate multiple rodent-adapted scrapie prions
Karla A. Schwenke et al.
SCIENTIFIC REPORTS (2022)
Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders
Aurelie de Rus Jacquet et al.
MOLECULAR PSYCHIATRY (2021)
From Cell Culture to Organoids-Model Systems for Investigating Prion Strain Characteristics
Hailey Pineau et al.
BIOMOLECULES (2021)
Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt-Jakob disease
Bradley R. Groveman et al.
SCIENTIFIC REPORTS (2021)
Engineering organoids
Moritz Hofer et al.
NATURE REVIEWS MATERIALS (2021)
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Luise Linsenmeier et al.
SCIENCE ADVANCES (2021)
Effect of Scrapie Prion Infection in Ovine Bone Marrow-Derived Mesenchymal Stem Cells and Ovine Mesenchymal Stem Cell-Derived Neurons
Laura Garcia-Mendivil et al.
ANIMALS (2021)
Review on the Vascularization of Organoids and Organoids-on-a-Chip
Xingli Zhao et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)
Cell-Type-Specific High Throughput Toxicity Testing in Human Midbrain Organoids
Henrik Renner et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2021)
Propagation of CJD Prions in Primary Murine Glia Cells Expressing Human PrPc
Joo-Hee Waelzlein et al.
PATHOGENS (2021)
Anti-prion drug screening system in Saccharomyces cerevisiae based on an artificial [LEU2+] prion
Takao Ishikawa et al.
FUNGAL GENETICS AND BIOLOGY (2020)
Cellular models for discovering prion disease therapeutics: Progress and challenges
Saffire H. Krance et al.
JOURNAL OF NEUROCHEMISTRY (2020)
Do not keep it simple: recent advances in the generation of complex organoids
Philipp Woersdoerfer et al.
JOURNAL OF NEURAL TRANSMISSION (2020)
Novel regulators of PrP©expression as potential therapeutic targets in prion diseases
Arianna Colini Baldeschi et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2020)
POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research
Hailey Pineau et al.
BIOMOLECULES (2020)
Prion infection, transmission, and cytopathology modeled in a low-biohazard human cell line
Merve Avar et al.
LIFE SCIENCE ALLIANCE (2020)
Highly infectious prions are not directly neurotoxic
Iryna Benilova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid- oligomers
Heledd H. Jarosz-Griffiths et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Engineering a murine cell line for the stable propagation of hamster prions
Matthew E. C. Bourkas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
Carlo Scialo et al.
VIRUSES-BASEL (2019)
Gene-edited murine cell lines for propagation of chronic wasting disease prions
Rupali Walia et al.
SCIENTIFIC REPORTS (2019)
Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids
Bradley R. Groveman et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Anti-prion Butenolides and Diphenylpropanones from the Australian Ascidian Polycarpa procera
Laurence K. Jennings et al.
JOURNAL OF NATURAL PRODUCTS (2019)
Genome-wide identification of microRNAs regulating the human prion protein
Daniel Pease et al.
BRAIN PATHOLOGY (2019)
Animal prion diseases: the risks to human health
Fiona Houston et al.
BRAIN PATHOLOGY (2019)
Organotypic brain slice cultures to model neurodegenerative proteinopathies
C. L. Croft et al.
MOLECULAR NEURODEGENERATION (2019)
Human Brain Slice Culture: A Useful Tool to Study Brain Disorders and Potential Therapeutic Compounds
Xin-Rui Qi et al.
NEUROSCIENCE BULLETIN (2019)
Identifying Anti-prion Chemical Compounds Using a Newly Established Yeast High-Throughput Screening System
Zhiqiang Du et al.
CELL CHEMICAL BIOLOGY (2019)
iPS Cell Cultures from a Gerstmann-Straussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology
Andreu Matamoros-Angles et al.
MOLECULAR NEUROBIOLOGY (2018)
Yeast-based screening of natural product extracts results in the identification of prion inhibitors from a marine sponge
Laurence K. Jennings et al.
PRION (2018)
Cellular and Molecular Mechanisms of Prion Disease
Christina J. Sigurdson et al.
Annual Review of Pathology-Mechanisms of Disease (2018)
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity
Marco Bardelli et al.
PLOS PATHOGENS (2018)
Insights from Therapeutic Studies for PrP Prion Disease
Kenta Teruya et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)
Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner
Zuzana Krejciova et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Analysis of [SWI+] formation and propagation events
Zhiqiang Du et al.
MOLECULAR MICROBIOLOGY (2017)
Neural organoids for disease phenotyping, drug screening and developmental biology studies
Brigham J. Hartley et al.
NEUROCHEMISTRY INTERNATIONAL (2017)
Chronic wasting disease prion infection of differentiated neurospheres
Yoshifumi Iwamaru et al.
PRION (2017)
Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity
Despoina Goniotaki et al.
PLOS PATHOGENS (2017)
Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency
Samia Hannaoui et al.
PLOS PATHOGENS (2017)
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Michiru Nishita et al.
SCIENTIFIC REPORTS (2017)
Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases
Misol Ahn et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2016)
The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
Alexander Kuffer et al.
NATURE (2016)
A transfectant RK13 cell line permissive to classical caprine scrapie prion propagation
Rohana P. Dassanayake et al.
PRION (2016)
Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis
Johanna F. Dekkers et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
A Neuronal Culture System to Detect Prion Synaptotoxicity
Cheng Fang et al.
PLOS PATHOGENS (2016)
Modeling mouse and human development using organoid cultures
Meritxell Huch et al.
DEVELOPMENT (2015)
Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease
Leonardo M. Cortez et al.
JOURNAL OF VIROLOGY (2015)
The Standard Scrapie Cell Assay: Development, Utility and Prospects
Jacques van der Merwe et al.
VIRUSES-BASEL (2015)
Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie
Hanna Wolf et al.
FRONTIERS IN NEUROSCIENCE (2015)
A Bovine Cell Line That Can Be Infected by Natural Sheep Scrapie Prions
Anja M. Oelschlegel et al.
PLOS ONE (2015)
Generation of a Persistently Infected MDBK Cell Line with Natural Bovine Spongiform Encephalopathy (BSE)
Dongseob Tark et al.
PLOS ONE (2015)
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains
Kurt Giles et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Cycline Efficacy on the Propagation of Human Prions in Primary Cultured Neurons is Strain-Specific
Samia Hannaoui et al.
JOURNAL OF INFECTIOUS DISEASES (2014)
Functional Cross-Talk Between the Cellular Prion Protein and the Neural Cell Adhesion Molecule is Critical for Neuronal Differentiation of Neural Stem/Precursor Cells
Kanella Prodromidou et al.
STEM CELLS (2014)
PrPC Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus
Maddalena D. Caiati et al.
JOURNAL OF NEUROSCIENCE (2013)
Prion Propagation and Toxicity Occur In Vitro with Two-Phase Kinetics Specific to Strain and Neuronal Type
Samia Hannaoui et al.
JOURNAL OF VIROLOGY (2013)
Prion Replication Elicits Cytopathic Changes in Differentiated Neurosphere Cultures
Yoshifumi Iwamaru et al.
JOURNAL OF VIROLOGY (2013)
Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease
Michael D. Geschwind et al.
NEUROLOGY (2013)
Drug resistance confounding prion therapeutics
David B. Berry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents
Yervand Eduard Karapetyan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cell-to-cell propagation of infectious cytosolic protein aggregates
Julia P. Hofmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Infectious Prions Accumulate to High Levels in Non Proliferative C2C12 Myotubes
Allen Herbst et al.
PLOS PATHOGENS (2013)
Prion Replication Occurs in Endogenous Adult Neural Stem Cells and Alters Their Neuronal Fate: Involvement of Endogenous Neural Stem Cells in Prion Diseases
Aroa Relano-Gines et al.
PLOS PATHOGENS (2013)
Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates
Ilan Margalith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A Brain Aggregate Model Gives New Insights Into the Pathobiology and Treatment of Prion Diseases
Krystyna Bajsarowicz et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
Probing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusions
Lyne Josse et al.
PRION (2012)
Prion Pathogenesis Is Faithfully Reproduced in Cerebellar Organotypic Slice Cultures
Jeppe Falsig et al.
PLOS PATHOGENS (2012)
Less protease-resistant PrP in a patient with sporadic CJD treated with intraventricular pentosan polysulphate
T. Terada et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
Prion infection of differentiated neurospheres
Maria Eugenia Herva et al.
JOURNAL OF NEUROSCIENCE METHODS (2010)
Discovery of 2-Aminothiazoles as Potent Antiprion Compounds
Sina Ghaemmaghami et al.
JOURNAL OF VIROLOGY (2010)
Cell-Based Quantification of Chronic Wasting Disease Prions
Jifeng Bian et al.
JOURNAL OF VIROLOGY (2010)
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo
Kristina Endres et al.
NEUROBIOLOGY OF DISEASE (2009)
Prion neurodegeneration Starts and stops at the synapse
Giovanna R. Mallucci
PRION (2009)
Continuous Quinacrine Treatment Results in the Formation of Drug-Resistant Prions
Sina Ghaemmaghami et al.
PLOS PATHOGENS (2009)
A cell line infectible by prion strains from different species
M. -P. Courageot et al.
JOURNAL OF GENERAL VIROLOGY (2008)
Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions
Deborah Tribouillard-Tanvier et al.
PLOS ONE (2008)
A γ-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains
Patricia Spilman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A versatile prion replication assay in organotypic brain slices
Jeppe Falsig et al.
NATURE NEUROSCIENCE (2008)
Prion strain discrimination in cell culture: The cell panel assay
Sukhvir P. Mahal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Cell division modulates prion accumulation in cultured cells
Sina Ghaemmaghami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Strengths and limitations of the neurosphere culture system
Josephine B. Jensen et al.
MOLECULAR NEUROBIOLOGY (2006)
Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease
Chad Johnson et al.
JOURNAL OF GENERAL VIROLOGY (2006)
Prion infection of mouse neurospheres
RK Giri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles
Romolo Nonno et al.
PLOS PATHOGENS (2006)
Preparation of organotypic hippocampal slice cultures for long-term live imaging
Nadine Gogolla et al.
NATURE PROTOCOLS (2006)
Treatment of transmissible spongiform encephalopathy by intraventricular drug infusion in animal models
K Doh-Ura et al.
JOURNAL OF VIROLOGY (2004)
New inhibitors of scrapie-associated prion protein formation in a library of 2,000 drugs and natural products
DA Kocisko et al.
JOURNAL OF VIROLOGY (2003)
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
PC Klöhn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Isolation of drugs active against mammalian prions using a yeast-based screening assay
S Bach et al.
NATURE BIOTECHNOLOGY (2003)
Shattuck lecture - Neurodegenerative diseases and prions.
SB Prusiner
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Interactions between prion protein isoforms: the kiss of death?
B Caughey
TRENDS IN BIOCHEMICAL SCIENCES (2001)
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
D Vilette et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Share Paper
