Journal
EUROSURVEILLANCE
Volume 27, Issue 36, Pages -Publisher
EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES.2022.27.36.2200675
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The study found that the monkeypox virus could be detected in anal and urethral samples from confirmed cases, with actively-replicating virus still present within 7 days from symptom onset. It was also discovered that asymptomatic secondary cases may support a potential sexual transmission hypothesis.
Anal and urethral samples from confirmed cases of monkeypox were screened for monkeypox virus (MPXV) by real-time PCR. Isolation of the virus was subsequently attempted in cell culture. Actively -replicating virus was demonstrated in 13 of 18 and 11 of 15 PCR-positive anal and urethral swabs, respec-tively, collected within 7 days from symptoms onset. Two asymptomatic secondary cases had detectable MPXV genetic material in urethral secretion and for one, MPXV was successfully isolated, supporting a potential MPXV sexual transmission hypothesis.
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