4.7 Article

Recent advances in electrospun nanofibers for wound dressing

Journal

EUROPEAN POLYMER JOURNAL
Volume 178, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2022.111490

Keywords

Electrospun nanofibers; Wound dressing; Polymer materials; Structure; Function

Funding

  1. Postdoctoral Research Foundation of General Hospital of Central Theater Command of PLA [BSH028]
  2. Natural Science Foundation of Hubei Province [2020CFB210]
  3. National Natural Science Foundation of China [82102340]

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Electrospun nanofibers have emerged as a promising option for wound dressings, with their high porosity, good mechanical properties, and excellent biocompatibility. They can promote wound healing by moisturizing the wound, facilitating cell respiration, and regenerating damaged skin. Furthermore, their ability to encapsulate active substances or incorporate them into their structural design allows them to meet the diverse requirements of wound therapy. This review article provides an overview of the recent developments in electrospun nanofibers as wound dressings, including the use of different polymer materials, their structural characteristics, and their role in promoting wound healing. The article also explores the future prospects of electrospinning in the development of wound dressings.
Electrospun nanofibers have been widely used recently as dressings for wound healing. They have high porosity, good mechanical properties, and excellent biocompatibility; as a result, they help to moisten wounds, promote cell respiration, and regenerate damaged skin. In addition, nanofibers can achieve the different requirements of wound therapy by encapsulating active substances or being incorporated in their structural design. Here, the most recent (since 2018) developments of electrospun nanofibers as wound dressings are reviewed, including polymer materials, structure characteristics and the function of promoting wound healing. Furthermore, the development prospects of wound dressings prepared by electrospinning are put forward.

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