Related references
Note: Only part of the references are listed.Targeting ERK induced cell death and p53/ROS-dependent protective autophagy in colorectal cancer
Wunan Mi et al.
CELL DEATH DISCOVERY (2021)
p38 MAPK pathway-dependent SUMOylation of Elk-1 and phosphorylation of PIAS2 correlate with the downregulation of Elk-1 activity in heat-stressed HeLa cells
Daipayan Chowdhury et al.
CELL STRESS & CHAPERONES (2019)
Targeting the ERK Signaling Pathway in Melanoma
Paola Savoia et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Targeting ERK1/2 protein-serine/threonine kinases in human cancers
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2019)
Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening
Chun-Yeung Lo et al.
SCIENTIFIC REPORTS (2018)
Trypanosoma cruzi induces cellular proliferation in the trophoblastic cell line BeWo
Daniel Droguett et al.
EXPERIMENTAL PARASITOLOGY (2017)
A compendium of ERK targets
Evrim B. Uenal et al.
FEBS LETTERS (2017)
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling
Andrew M. Kidger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
RAS and downstream RAF-MEK and PI3K-AKT signaling in neuronal development, function and dysfunction
Jian Zhong
BIOLOGICAL CHEMISTRY (2016)
The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids
Mercedes Soares-Silva et al.
FRONTIERS IN MICROBIOLOGY (2016)
Functional studies of TcRjl, a novel GTPase of Trypanosoma cruzi, reveals phenotypes related with MAPK activation during parasite differentiation and after heterologous expression in Drosophila model system
Guilherme Rodrigo Reis Monteiro dos-Santos et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Targeting RAS-ERK signalling in cancer: promises and challenges
Ahmed A. Samatar et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
Matthew Brentnall et al.
BMC CELL BIOLOGY (2013)
RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer
Violeta Serra et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Intermittent Administration of MEK Inhibitor GDC-0973 plus PI3K Inhibitor GDC-0941 Triggers Robust Apoptosis and Tumor Growth Inhibition
Klaus P. Hoeflich et al.
CANCER RESEARCH (2012)
Combinations of BRAF, MEK, and PI3K/mTOR Inhibitors Overcome Acquired Resistance to the BRAF Inhibitor GSK2118436 Dabrafenib, Mediated by NRAS or MEK Mutations
James G. Greger et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma
Keith T. Flaherty et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling
Nikhil Wagle et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
BRAFV600E: Implications for Carcinogenesis and Molecular Therapy
Emma R. Cantwell-Dorris et al.
MOLECULAR CANCER THERAPEUTICS (2011)
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
Poulikos I. Poulikakos et al.
NATURE (2011)
Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)
Hiroyuki Abe et al.
ACS MEDICINAL CHEMISTRY LETTERS (2011)
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
Gideon Bollag et al.
NATURE (2010)
ROS-Mediated p38α MAPK Activation and ERK Inactivation Responsible for Upregulation of Fas and FasL and Autocrine Fas-Mediated Cell Death in Taiwan Cobra Phospholipase A2-Treated U937 Cells
Wen-Hsin Liu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Synthesis, Oxidant Properties, and Antitumoral Effects of a Heteroleptic Palladium(II) Complex of Curcumin on Human Prostate Cancer Cells
Alessandra Valentini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
MEK1 mutations confer resistance to MEK and B-RAF inhibition
Caroline M. Emery et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma
Clara Montagut et al.
CANCER RESEARCH (2008)
Atypical mitogen-activated protein kinases: Structure, regulation and functions
Phillipe Coulombe et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-Akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells
Sanjeev Shukla et al.
CELL CYCLE (2007)
Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma
Hung Huynh et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Non-irradiation-derived reactive oxygen species (ROS) and cancer: therapeutic implications
E. Agostinelli et al.
AMINO ACIDS (2006)
Caspase-9 and effector caspases have sequential and distinct effects on mitochondria
E Cepero et al.
ONCOGENE (2005)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
Role of reactive oxygen species (ROS) in apoptosis induction
HU Simon et al.
APOPTOSIS (2000)