Related references
Note: Only part of the references are listed.Alpha-Ketoglutarate dietary supplementation to improve health in humans
Bibek Gyanwali et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2022)
Current updates and future perspectives on the management of renal cell carcinoma
Deepika Singh
LIFE SCIENCES (2021)
Cell death pathways: intricate connections and disease implications
Matthias Kist et al.
EMBO JOURNAL (2021)
Pleiotropic effects of alpha-ketoglutarate as a potential anti-ageing agent
Maria M. Bayliak et al.
AGEING RESEARCH REVIEWS (2021)
Autophagy as a Vital Therapy Target for Renal Cell Carcinoma
Ying-hua He et al.
FRONTIERS IN PHARMACOLOGY (2021)
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
Damien Bertheloot et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
The Regulatory Role of α-Ketoglutarate Metabolism in Macrophages
Shaojuan Liu et al.
MEDIATORS OF INFLAMMATION (2021)
Reactive Oxygen Species (ROS) Regulates Different Types of Cell Death by Acting as a Rheostat
Gloria E. Villalpando-Rodriguez et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2021)
Di-2-ethylhexyl phthalate (DEHP) induces apoptosis and autophagy of mouse GC-1 spg cells
Yu Gan et al.
ENVIRONMENTAL TOXICOLOGY (2020)
Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells
Tairine Zara Lopes et al.
BIOMEDICINE & PHARMACOTHERAPY (2020)
Autophagy and autophagy-related proteins in cancer
Xiaohua Li et al.
MOLECULAR CANCER (2020)
Mitochondrial TCA cycle metabolites control physiology and disease
Inmaculada Martinez-Reyes et al.
NATURE COMMUNICATIONS (2020)
Targeting Strategies for Renal Cancer Stem Cell Therapy
Pengchao Fang et al.
CURRENT PHARMACEUTICAL DESIGN (2020)
Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours
Fei Xu et al.
CELL AND BIOSCIENCE (2020)
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice
Azar Asadi Shahmirzadi et al.
CELL METABOLISM (2020)
Biochemical pathways to α-ketoglutarate, a multi-faceted metabolite
F. Legendre et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2020)
Autophagy in Human Diseases
Noboru Mizushima et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Costunolide Induces Autophagy and Apoptosis by Activating ROS/MAPK Signaling Pathways in Renal Cell Carcinoma
Dian Fu et al.
FRONTIERS IN ONCOLOGY (2020)
Alpha Ketoglutarate Exerts In Vitro Anti-Osteosarcoma Effects through Inhibition of Cell Proliferation, Induction of Apoptosis via the JNK and Caspase 9-Dependent Mechanism, and Suppression of TGF-β and VEGF Production and Metastatic Potential of Cells
Katarzyna Kalawaj et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Challenges and Therapeutic Opportunities of Autophagy in Cancer Therapy
Valdenizia R. Silva et al.
CANCERS (2020)
Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy
Zhenru Xu et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)
Epidemiology of Renal Cell Carcinoma
Umberto Capitanio et al.
EUROPEAN UROLOGY (2019)
Alpha-ketoglutarate extends Drosophila lifespan by inhibiting mTOR and activating AMPK
Yuan Su et al.
AGING-US (2019)
α-Ketoglutarate links p53 to cell fate during tumour suppression
John P. Morris et al.
NATURE (2019)
ROS and the DNA damage response in cancer
Upadhyayula Sai Srinivas et al.
REDOX BIOLOGY (2019)
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of advanced renal cell carcinoma (RCC)
Brian Rini et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
alpha-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis
Sandra Atlante et al.
CELL DEATH & DISEASE (2018)
Thymoquinone inhibits the metastasis of renal cell cancer cells by inducing autophagy via AMPK/mTOR signaling pathway
Yujiao Zhang et al.
CANCER SCIENCE (2018)
Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use
Barbara Zdzisinska et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2017)
Bisphenol A Induces Autophagy and Apoptosis Concurrently Involving the Akt/mTOR Pathway in Testes of Pubertal SD Rats
Chao Quan et al.
ENVIRONMENTAL TOXICOLOGY (2017)
Autophagy: The spotlight for cellular stress responses
Palaniyandi Ravanan et al.
LIFE SCIENCES (2017)
Treatment of renal cell carcinoma: Current status and future directions
Pedro C. Barata et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2017)
Targeting autophagy in cancer
Jean M. Mulcahy Levy et al.
NATURE REVIEWS CANCER (2017)
Survival among patients with advanced renal cell carcinoma in the pretargeted versus targeted therapy eras
Pengxiang Li et al.
CANCER MEDICINE (2016)
The glutamine-alpha-ketoglutarate (AKG) metabolism and its nutritional implications
Dingfu Xiao et al.
AMINO ACIDS (2016)
Alpha-Ketoglutarate: Physiological Functions and Applications
Nan Wu et al.
BIOMOLECULES & THERAPEUTICS (2016)
Management of Renal Masses and Localized Renal Cancer: Systematic Review and Meta-Analysis
Phillip M. Pierorazio et al.
JOURNAL OF UROLOGY (2016)
EAU Guidelines on Renal Cell Carcinoma: 2014 Update
Borje Ljungberg et al.
EUROPEAN UROLOGY (2015)
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey et al.
NATURE (2015)
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
David Heras-Sandoval et al.
CELLULAR SIGNALLING (2014)
Krebs cycle dysfunction shapes epigenetic landscape of chromatin: Novel insights into mitochondrial regulation of aging process
Antero Salminen et al.
CELLULAR SIGNALLING (2014)
Renal cell carcinoma
Eric Jonasch et al.
BMJ-BRITISH MEDICAL JOURNAL (2014)
Targeting PI3K/Akt/mTOR signaling in cancer
Camillo Porta et al.
FRONTIERS IN ONCOLOGY (2014)
Autophagy and genomic integrity
A. T. Vessoni et al.
CELL DEATH AND DIFFERENTIATION (2013)
Alpha-ketoglutarate (AKG) inhibits proliferation of colon adenocarcinoma cells in normoxic conditions
Wojciech Rzeski et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2012)
The Role of Autophagy in Cancer: Therapeutic Implications
Zhineng J. Yang et al.
MOLECULAR CANCER THERAPEUTICS (2011)
HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression
Daniel A. Tennant et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2010)
Autophagy: cellular and molecular mechanisms
Danielle Glick et al.
JOURNAL OF PATHOLOGY (2010)
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
Michael Degtyarev et al.
JOURNAL OF CELL BIOLOGY (2008)
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
Y. Chen et al.
CELL DEATH AND DIFFERENTIATION (2008)