Trends and thresholds on bacterial degradation of bisphenol-A endocrine disruptor - a concise review

Bisphenol-A (BPA) is a monomer found in polycarbonate plastics, food cans, and other everyday chemicals; this monomer and its counterparts are widely used, culminating in its presence in water, soil, sediment, and the atmosphere. Furthermore, because of its estrogenic and genotoxic properties, it has been acknowledged as an endocrine disruptor; contamination of BPA in the environment is becoming a growing concern, and ways to effectively mitigate BPA from the environment are currently explored. Hence, the focal point of the review is to collate the bacterial degradation of BPA with the proposed degradation mechanism, explicitly focusing on researches published between 2017 and 2022. BPA breakdown is dependent primarily on bacterial metabolism, although numerous factors influence its fate in the environment. The metabolic routes for BPA breakdown in crucial bacterial strains were postulated, sourced on the transformed metabolite-intermediates perceived through degradation; enzymes and genes associated with the bacterial degradation of BPA have also been included in this review. This review will be momentous to generate a conceptual strategy and stimulate the progress on bacterial mitigation of BPA as a path to a sustainable cleaner environment.

Automated summary

This review discusses the bacterial degradation of Bisphenol-A (BPA) and its proposed degradation mechanism, focusing on research published between 2017 and 2022. Bacterial metabolism plays a crucial role in BPA breakdown, and the metabolic routes have been postulated based on the transformed metabolite-intermediates observed during degradation. Additionally, enzymes and genes associated with bacterial degradation of BPA are also included in this review.