4.2 Article

Serum Sclerostin and Its Association with Bone Turnover Marker in Metabolic Bone Diseases

Related references

Note: Only part of the references are listed.
Article Endocrinology & Metabolism

Sclerostin antibody improves phosphate metabolism hormones, bone formation rates, and bone mass in adult Hyp mice

Kelsey A. Carpenter et al.

Summary: The study demonstrated the efficacy of monoclonal antibody to sclerostin (Scl-Ab) in treating skeletal and metabolic pathologies associated with XLH, improving bone mass, strength, and formation, and normalizing phosphate regulating hormones. It also provided evidence that Scl-Ab can target the bone-renal axis to improve phosphate regulation.
Article Pharmacology & Pharmacy

Drug discovery of sclerostin inhibitors

Sifan Yu et al.

Acta Pharmaceutica Sinica B (2022)

Article Endocrinology & Metabolism

Low Levels of Serum Sclerostin in Adult Patients With Tumor-Induced Osteomalacia Compared With X-linked Hypophosphatemia

Xiaolin Ni et al.

Summary: This study aimed to evaluate serum sclerostin levels in TIO patients compared with healthy controls and XLH patients, and analyze the correlations with bone mineral density (BMD) and laboratory parameters.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Article Endocrinology & Metabolism

Clinical and genetic analysis in 185 Chinese probands of osteogenesis imperfecta

Lei Xi et al.

Summary: This study analyzed mutations in main pathogenic genes, COL1A1 and COL1A2, and clinical characteristics of osteogenesis imperfecta in China. The study found that there were more sporadic cases than familial cases, and most patients presented with a history of fractures. Hotspot mutations G767S, D1219N in COL1A1 and G337S in COL1A2 were identified as frequent mutations in Chinese patients.

JOURNAL OF BONE AND MINERAL METABOLISM (2021)

Article Cell Biology

Clinical and Genetic Characteristics of 153 Chinese Patients With X-Linked Hypophosphatemia

Xiaoyun Lin et al.

Summary: This study provides a comprehensive description of the clinical profiles, circulating levels of iFGF23 and gene mutation features of patients with XLH. The findings show no evident correlation of circulating iFGF23 levels with the age or disease severity in patients with XLH.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Endocrinology & Metabolism

Sclerostin Antibody Treatment Increases Bone Mass and Normalizes Circulating Phosphate Levels in Growing Hyp Mice

Kelsey A. Carpenter et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2020)

Review Endocrinology & Metabolism

Osteogenesis imperfecta: an update on clinical features and therapies

Ronit Marom et al.

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2020)

Article Endocrinology & Metabolism

Bisphosphonates in the management of Paget's disease

Stuart H. Ralston

Review Medicine, General & Internal

Anti-Sclerostin Antibodies in Osteoporosis and Other Bone Diseases

Stephanie Fabre et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Urology & Nephrology

Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia

Dieter Haffner et al.

NATURE REVIEWS NEPHROLOGY (2019)

Article Medicine, General & Internal

Evaluation of Bone Metabolism Biomarkers in Paget's Disease of Bone

Glaucio R. Werner de Castro et al.

CUREUS JOURNAL OF MEDICAL SCIENCE (2019)

Article Endocrinology & Metabolism

Paget's disease of bone

Natasha M. Appelman-Dijkstra et al.

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Article Endocrinology & Metabolism

Genetics of Sost/SOST in sclerosteosis and van Buchem disease animal models

Aimy Sebastian et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2018)

Article Endocrinology & Metabolism

Paget's disease of bone

Tim Cundy

METABOLISM-CLINICAL AND EXPERIMENTAL (2018)

Article Endocrinology & Metabolism

BPS804 Anti-Sclerostin Antibody in Adults With Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial

Francis H. Glorieux et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2017)

Article Rheumatology

Circulating Dickkopf-1 and sclerostin in patients with Paget's disease of bone

Luca Idolazzi et al.

CLINICAL RHEUMATOLOGY (2017)

Article Endocrinology & Metabolism

Hormonal and systemic regulation of sclerostin

Matthew T. Drake et al.

Article Endocrinology & Metabolism

Role and mechanism of action of sclerostin in bone

Jesus Delgado-Calle et al.

Article Endocrinology & Metabolism

Circulating Sclerostin in Children and Young Adults with Heritable Bone Disorders

Telma Palomo et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Article Endocrinology & Metabolism

Serum Sclerostin Levels Are Decreased in Adult Patients With Different Types of Osteogenesis Imperfecta

Roland Kocijan et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2014)

Article Endocrinology & Metabolism

Cortical and Trabecular Bone Density in X-Linked Hypophosphatemic Rickets

Moira Cheung et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Endocrinology & Metabolism

Circulating Sclerostin Levels and Markers of Bone Turnover in Chinese-American and White Women

Aline G. Costa et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

Article Endocrinology & Metabolism

Sclerostin levels during growth in children

S. Kirmani et al.

OSTEOPOROSIS INTERNATIONAL (2012)

Article Multidisciplinary Sciences

Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway

Asiri R. Wijenayaka et al.

PLOS ONE (2011)

Article Endocrinology & Metabolism

Increased Sclerostin Serum Levels Associated with Bone Formation and Resorption Markers in Patients with Immobilization-Induced Bone Loss

Agostino Gaudio et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)