4.7 Article

The translation regulator Zar1l controls timing of meiosis in Xenopus oocytes

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Revisiting ZAR proteins: the understudied regulator of female fertility and beyond

Yu-Ke Wu et al.

Summary: Putative RNA-binding proteins, ZAR1 and ZAR2, have been identified as maternal factors involved in oogenesis and embryogenesis. The C-terminus of ZAR proteins, with a conserved CxxC structure, is reported to be the functional domain. ZAR proteins bind to maternal transcripts and inhibit translation in immature growing oocytes, but promote translation in fully grown mouse oocytes. Recent studies also suggest their involvement in tumorigenesis.

CELLULAR AND MOLECULAR LIFE SCIENCES (2022)

Article Biochemistry & Molecular Biology

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

Yasset Perez-Riverol et al.

Summary: PRIDE is the largest data repository of mass spectrometry-based proteomics data in the world, with around 500 datasets submitted per month. In addition to continuous improvements in data pipelines and infrastructure, PRIDE has developed the Spectra Archive and MAGE-TAB file format to enhance sample metadata annotation and access to mass spectra.

NUCLEIC ACIDS RESEARCH (2022)

Article Cell Biology

L-bodies are RNA protein condensates driving RNA localization in Xenopus oocytes

Christopher R. Neil et al.

Summary: Researchers have identified a new type of cytoplasmic RNP granule, named localization-bodies (L-bodies), containing vegetally localized RNA. These L-bodies consist of a dynamic protein-containing phase surrounding a nondynamic RNA-containing phase. RNA plays a critical role within these RNP granules, and cis-elements within localized mRNAs may regulate subcellular RNA localization by controlling phase behavior.

MOLECULAR BIOLOGY OF THE CELL (2021)

Article Biochemistry & Molecular Biology

Target-induced clustering activates Trim-Away of pathogens and proteins

Jingwei Zeng et al.

Summary: The article explains the working principle of Trim-Away, a new technology that utilizes TRIM21's ubiquitination activity for protein degradation, promoting virus neutralization or targeting disease-causing proteins. The study expands the understanding of TRIM21 and broadens the application of Trim-Away.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)

Article Cell Biology

The Recurrent Mutation in PATL2 Inhibits Its Degradation Thus Causing Female Infertility Characterized by Oocyte Maturation Defect Through Regulation of the Mos-MAPK Pathway

Qiqi Cao et al.

Summary: Mutations in PATL2, such as PATL2(Y217N), disrupt oocyte maturation by reducing ubiquitination levels and affecting translational regulation of Mos mRNA, leading to impaired MAPK signaling pathway and meiosis in oocytes. This highlights a new mechanism of action for PATL2 in maternal mRNA translation regulation during oocyte meiotic maturation.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Cell Biology

Distinct roles of two eIF4E isoforms in the germline of Caenorhabditis elegans

Hayden P. Huggins et al.

JOURNAL OF CELL SCIENCE (2020)

Article Cell Biology

4E-T-bound mRNAs are stored in a silenced and deadenylated form

Felix Rasch et al.

GENES & DEVELOPMENT (2020)

Article Biochemistry & Molecular Biology

Keeping the Proportions of Protein Complex Components in Check

James Christopher Taggart et al.

CELL SYSTEMS (2020)

Review Cell Biology

Managing the Oocyte Meiotic Arrest-Lessons from Frogs and Jellyfish

Catherine Jessus et al.

CELLS (2020)

Review Cell Biology

Regulation of Germ Cell mRNPs by eIF4E:4EIP Complexes: Multiple Mechanisms, One Goal

Hayden P. Huggins et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation

Chad E. Cragle et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

Sebastian Markmiller et al.

Article Biochemistry & Molecular Biology

Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex

Marcello Clerici et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex

Marcello Clerici et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

Arnaud Hubstenberger et al.

MOLECULAR CELL (2017)

Article Biochemistry & Molecular Biology

Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs

Laure Weill et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs

Laure Weill et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)

Article Biochemistry & Molecular Biology

A Method for the Acute and Rapid Degradation of Endogenous Proteins

Dean Clift et al.

Article Biochemistry & Molecular Biology

Widespread Influence of 3′-End Structures on Mammalian mRNA Processing and Stability

Xuebing Wu et al.

Article Biochemistry & Molecular Biology

Amyloid-like Self-Assembly of a Cellular Compartment

Elvan Boke et al.

Article Biochemistry & Molecular Biology

The DDX6-4E-T interaction mediates translational repression and P-body assembly

Anastasiia Kamenska et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Distinct Features of Cap Binding by eIF4E1b Proteins

Dorota Kubacka et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Zar1 represses translation in Xenopus oocytes and binds to the TCS in maternal mRNAs with different characteristics than Zar2

Tomomi M. Yamamoto et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2013)

Review Biochemistry & Molecular Biology

A mechanistic overview of translation initiation in eukaryotes

Colin Echeverria Aitken et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Translational control by changes in poly(A) tail length: recycling mRNAs

Laure Weill et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)

Article Multidisciplinary Sciences

The APC/C Inhibitor XErp1/Emi2 Is Essential for Xenopus Early Embryonic Divisions

Thomas Tischer et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Biochemical Characterization of Pumilio1 and Pumilio2 in Xenopus Oocytes

Ryoma Ota et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Duplex Unwinding and ATPase Activities of the DEAD-Box Helicase eIF4A Are Coupled by eIF4G and eIF4B

Ali R. Oezes et al.

JOURNAL OF MOLECULAR BIOLOGY (2011)

Article Developmental Biology

Translational repression by the oocyte-specific protein P100 in Xenopus

Yoriko Nakamura et al.

DEVELOPMENTAL BIOLOGY (2010)

Review Cell Biology

The mechanism of eukaryotic translation initiation and principles of its regulation

Richard J. Jackson et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Veterinary Sciences

Expression of chicken zygote arrest 1 (Zar1) and Zar1-like genes during sexual maturation and embryogenesis

Georgios Michailidis et al.

VETERINARY RESEARCH COMMUNICATIONS (2010)

Article Biochemical Research Methods

Jalview Version 2-a multiple sequence alignment editor and analysis workbench

Andrew M. Waterhouse et al.

BIOINFORMATICS (2009)

Review Biochemistry & Molecular Biology

Translational control by cytoplasmic polyadenylation in Xenopus oocytes

Helois E. Radford et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2008)

Article Biochemistry & Molecular Biology

A putative protein structurally related to zygote arrest 1 (Zar1), Zar1-like, is encoded by a novel gene conserved in the vertebrate lineage

Lorenzo Sangiorgio et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

CPEB interacts with an ovary-specific eIF4E and 4E-T in early Xenopus oocytes

Nicola Minshall et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Primer3Plus, an enhanced web interface to Primer3

Andreas Untergasser et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Biochemistry & Molecular Biology

Regulation of Cdc25C by ERK-MAP kinases during the G2/M transition

Ruoning Wang et al.

Article Biochemistry & Molecular Biology

Musashi regulates the temporal order of mRNA translation during Xenopus oocyte maturation

Amanda Charlesworth et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Redundant pathways for Cdc2 activation in Xenopus oocyte:: either cyclin B or Mos synthesis

O Haccard et al.

EMBO REPORTS (2006)

Article Cell Biology

Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation

K Padmanabhan et al.

GENES & DEVELOPMENT (2006)

Article Biochemistry & Molecular Biology

Embryonic poly(A)-binding protein stimulates translation in germ cells

GS Wilkie et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation

DC Barnard et al.

Article Reproductive Biology

Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries

XM Wu et al.

BIOLOGY OF REPRODUCTION (2003)

Article Biochemistry & Molecular Biology

A novel regulatory element determines the timing of Mos mRNA translation during Xenopus oocyte maturation

A Charlesworth et al.

EMBO JOURNAL (2002)

Article Cell Biology

Cyclin B/cdc2 induces c-Mos stability by direct phosphorylation in Xenopus oocytes.

A Castro et al.

MOLECULAR BIOLOGY OF THE CELL (2001)

Article Biochemistry & Molecular Biology

The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90Rsk

SD Gross et al.

CURRENT BIOLOGY (2000)