Journal
DERMATOLOGIC THERAPY
Volume 35, Issue 12, Pages -Publisher
WILEY-HINDAWI
DOI: 10.1111/dth.15923
Keywords
acute febrile neutrophilic dermatosis; erythema nodosum; oral ulcerations; Sweet syndrome; vaccination
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This article presents a case of acute febrile neutrophilic dermatosis (Sweet syndrome-SS) after Ad26.COV2.S vaccination, emphasizing the importance of sharing knowledge and experience on the clinical manifestations and underlying causes of this disease.
The aim of this article is to present the case of acute febrile neutrophilic dermatosis (Sweet syndrome-SS) after Ad26.COV2.S vaccination against SARS-CoV-2. To the best of our knowledge, this is the second case of SS provoked by this specific vaccine. What is more, the mildly symptomatic beginning of the disease, later followed by typical SS manifestation with a variety of symptoms including nodular erythema of the feet and oral ulcerations, made it very challenging to establish the diagnosis. The article focuses on the current literature on the acute febrile neutrophilic dermatosis, along with the coexistence with other neutrophilic dermatoses and anti-SARS-CoV-2 vaccinations as provoking factors. It emphasizes the necessity for sharing the knowledge and experience on the subject of SS's clinical manifestations and underlying causes to facilitate prompt diagnosis and introduction of appropriate treatment.
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