4.3 Review

Intensive care management of liver transplant recipients

Journal

CURRENT OPINION IN CRITICAL CARE
Volume 28, Issue 6, Pages 709-714

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCC.0000000000001002

Keywords

biliary complications; hepatic artery thrombosis; intensive care; liver transplantation; primary graft nonfunction

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Liver transplantation is the only definitive treatment for advanced liver disease and liver failure. The number of liver transplantations is increasing globally due to the rising prevalence of liver disease. Intensive care providers need to possess knowledge of technical considerations, basic management, and common complications related to liver transplantation.
Purpose of review Liver transplantation remains the only definitive treatment for advanced liver disease and liver failure. Current allocation schemes utilized for liver transplantation mandate a 'sickest first' approach, thus most liver transplants occur in patients with severe systemic illness. For intensive care providers who care for liver transplant recipients, a foundation of knowledge of technical considerations of orthotopic liver transplantation, basic management considerations, and common complications is essential. This review highlights the authors' approach to intensive care management of the postoperative liver transplant recipient with a review of common issues, which arise in this patient population. Recent findings The number of centers offering liver transplantation continues to increase globally and the number of patients receiving liver transplantation also continues to increase. The number of patients with advanced liver disease far outpaces organ availability and, therefore, patients undergoing liver transplant are sicker at the time of transplant. Outcomes for liver transplant patients continue to improve owing to advancements in surgical technique, immunosuppression management, and intensive care management of liver disease both pretransplant and posttransplant. Given a global increase in liver transplantation, an increasing number of intensive care professionals are likely to care for this patient population. For these providers, a foundational knowledge of the common complications and key management considerations is essential.

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