Journal
CURRENT MEDICINAL CHEMISTRY
Volume 30, Issue 23, Pages 2672-2689Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867329666220823113415
Keywords
2-Oxazolidinones; various biological activities; anti-tumor; anti-virus; anti-inflammation; anti-coagulant
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2-Oxazolidinone is commonly used as a pharmacophore for antibacterial agents, such as Linezolid and Tedizolid. However, recent research has revealed various biological activities of 2-oxazolidinones beyond their antibacterial properties. In this review, we provide an overview of the progress in this unconventional area of 2-oxazolidinones over the past 10 years (2011-2021).
2-Oxazolidinone is well known as a pharmacophore for antibacterial agents represented by two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing reports on the various biological activities of 2-oxazolidinones beyond antibacterial activities. Therefore, in this review, we provide an overview of the progress of this untraditional area of 2-oxazolidinones in the past 10 years (2011-2021).
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