Journal
COORDINATION CHEMISTRY REVIEWS
Volume 470, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ccr.2022.214703
Keywords
Carbon dots; NIR fluorescence; Luminescence mechanism; Phototherapy; Biomedical imaging
Categories
Funding
- National Natural Science Founda- tion of China [62175262]
- Fundamental Research Funds for the Central South Universities [2020CX021]
- Key R & D plan of Hunan Province [2022SK2101]
- Technological Innova- tion Research Program of Huaihua City [2021N3702]
Ask authors/readers for more resources
Carbon dots (CDs) are nanomaterials with excellent properties that are used in biomedical imaging and cancer therapy. Near-infrared fluorescent CDs have good tissue penetration ability and can achieve high-resolution fluorescence imaging of deep tissues, showing great potential in the biomedical field. This review systematically summarizes the synthesis strategies, luminescence mechanisms, and biomedical applications of near-infrared fluorescent CDs in the past 10 years, and discusses the challenges and perspectives in their synthesis and applications.
Carbon dots (CDs) are widely used in biomedical imaging and cancer therapy due to their excellent water solubility, low toxicity, satisfying biocompatibility, and good tissue permeability. Among them, near -infrared (NIR) fluorescent CDs (kem > 650 nm) could effectively avoid the interference of spontaneous bio-logical fluorescence, have strong tissue penetration ability, which can realize high-resolution fluores-cence imaging of deep tissues, and hence show great potential in the biomedical field. Therefore, the controlled synthesis and regulation the photochemical and photophysical properties of NIR fluorescent CDs has also become a research hotspot. This review aimed to systematically summarize the synthesis strategies, luminescence mechanisms, and biomedical applications of NIR fluorescent CDs in the last 10 years. The challenges and perspectives in the synthesis and applications of NIR fluorescent CDs were also discussed.(c) 2022 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available