Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 54, Issue 1, Pages 753-757Publisher
WILEY
DOI: 10.1002/jhet.2617
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One-pot reaction of cyclic 1,3-diketones, dimethylformamide dimethylacetal ( DMFDMA) and 2-(1H-benzo[ d] imidaz-2-yl) acetonitrile was found to be a highly selective process leading to 4-oxo-1,2,3,4-tetrahydrobenzo[ 4,5] imidazo[ 1,2- a] quinolin-6-yl cyanides. Optimized reaction conditions using water as solvent at room temperature or under microwave heating allowed high yields of the target products required no additional purification.
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