Schiff base compounds as artificial metalloenzymes

Much research has been done on traditional homogeneous metal catalysts and enzymatic catalysts, but recently a new class of hybrid catalysts called synthetic (artificial) metalloenzymes has been considered by researchers. Metalloenzymes as hybrid catalysts (host-guest systems) have been shown that combine the properties of a homogeneous and also enzymatic catalyst. The hybrid catalyst will have added value such as enantioselectivity or chemo-selectivity. This review focuses on Schiff base complexes that either act as homogeneous artificial enzymes or contribute to the structure of a host in the preparation of hybrid metalloenzymes. Because this approach can virtually be applied to any bio-or synthetic host or guest coordination complex, the details of hybrid catalysts seem important for advance in catalysis.

Automated summary

Extensive research has been conducted on traditional homogeneous metal catalysts and enzymatic catalysts. However, a new type of hybrid catalyst called synthetic metalloenzymes has recently gained attention. Combining the properties of both homogeneous and enzymatic catalysts, metalloenzymes demonstrate added value such as enantioselectivity or chemo-selectivity. This review focuses on Schiff base complexes, which act as either homogeneous artificial enzymes or contribute to the structure of host in the preparation of hybrid metalloenzymes. The details of hybrid catalysts are crucial for advancements in catalysis, as this approach can be applied to various bio- or synthetic host and guest coordination complexes.