4.6 Article

A facile electrochemical sensor based on green synthesis of Cs/Ce-MOF for detection of tryptophan in human serum

Publisher

ELSEVIER
DOI: 10.1016/j.colsurfa.2022.129225

Keywords

Electrochemical sensor; Metal-organic frameworks; Tryptophan

Funding

  1. National Natural Science Foundation of China [52172092]
  2. Natural Science Foundation of Heilongjiang Province [LH2021B029]
  3. Key Research and Develop-ment Guidance Projects in Heilongjiang Province [GZ20210034]
  4. Opening Foundation of Heilongjiang Provincial Key Laboratory of Polymeric Composition Materials [CLKFKT2021B9]
  5. Funda-mental Research Fund of Heilongjiang Provincial University [145109118]
  6. Major Research Plan Na-tional Natural Science Foundation of China [92061102]
  7. National Natural Science Foundation of China [52172092]
  8. Natural Science Foundation of Heilongjiang Province [LH2021B029]
  9. Key Research and Development Guidance Projects in Heilongjiang Province [GZ20210034]
  10. Opening Foundation of Heilongjiang Provincial Key Laboratory of Polymeric Composition Materials [CLKFKT2021B9]
  11. Fundamental Research Fund of Heilongjiang Provincial University [145109118]
  12. Major Research Plan National Natural Science Foundation of China [92061102]

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A facile electrochemical sensor for tryptophan detection was developed using Cs/Ce-MOF modified electrode, which demonstrated excellent performance and potential applications.
A facile electrochemical sensor for tryptophan detection was designed and constructed by using Cs/Ce-MOF modified glass carbon electrode. The synthesis strategy of Cs/Ce-MOF composite not only greatly saved both energy and time costs, but also prevented the aggregation of Ce-MOF. The electrochemical sensor possessed excellent performance with wide linear range (0.25-331 mu M) and a low limit of detection (0.14 mu M), which is due to the good film-forming ability, permeability and rich accessible active sites. Additionally, the as-prepared electrochemical sensor has good selectivity, reproducibility, repeatability, stability and potential application in real samples.

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