Frequency of subclavian artery stenosis in patients with mammarian artery coronary bypass and suspected coronary artery disease progression

We retrospectively analyzed patient records of all patients with a history of internal mammarian artery (IMA) coronary bypass undergoing coronary angiography at two cardiovascular centers between January 1st 1999 and December 31st 2019. A total of 11,929 coronary angiographies with or without percutaneous coronary intervention were carried out in 3921 patients. Our analysis revealed 82 (2%) patients with documented subclavian artery stenosis. Of these, 8 (10%) patients were classified as having mild, 18 (22%) moderate, and 56 (68%) severe subclavian artery stenosis. In 7 (9%) patients with subclavian artery stenosis, angiography revealed occlusion of the IMA graft. 26 (32%) patients with severe subclavian artery stenosis underwent endovascular or surgical revasculararization of the subclavian artery. In this retrospective multicenter study, subclavian artery stenosis was a relevant finding in patients with an internal mammarian artery coronary bypass graft undergoing coronary angiography. The development of dedicated algorithms for screening and ischemia evaluation in affected individuals may improve treatment of this potentially underdiagnosed and undertreated condition.

Automated summary

This retrospective multicenter study analyzed patient records of internal mammary artery coronary bypass patients undergoing coronary angiography and found that subclavian artery stenosis was a relevant finding in these patients. Among the patients with severe stenosis, 32% underwent endovascular or surgical revascularization. Developing dedicated algorithms for screening and ischemia evaluation may improve treatment for this potentially underdiagnosed and undertreated condition.