Dual Antiviral Therapy for Persistent Coronavirus Disease 2019 and Associated Organizing Pneumonia in an Immunocompromised Host

The management of patients with prolonged viral shedding and coronavirus disease 2019 symptoms remains unclear. Combining antivirals, as practiced in other infections, is theoretically advantageous. We present a case of persistent, symptomatic severe acute respiratory syndrome coronavirus 2 infection and associated organizing pneumonia that was successfully treated with an extended course of combination antiviral therapy.

Automated summary

The management of patients with prolonged viral shedding and COVID-19 symptoms is still unclear. This study presents a case of successful treatment of a patient with persistent, symptomatic severe acute respiratory syndrome coronavirus 2 infection and associated organizing pneumonia using an extended course of combination antiviral therapy.