Helmet vs Facemask CPAP in COVID-19 Respiratory Failure A Prospective Cohort Study

Letter Critical Care Medicine

Phenotypes of Patients with COVID-19 Who Have a Positive Clinical Response to Helmet Noninvasive Ventilation

Domenico Luca Grieco et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)

Review Critical Care Medicine

Noninvasive respiratory support for acute respiratory failure due to COVID-19

Luca S. Menga et al.

Summary: This narrative review discusses the benefits and possible harms of noninvasive respiratory support for COVID-19 respiratory failure. Maintaining spontaneous breathing in hypoxemic patients with vigorous effort carries the risk of patient self-induced lung injury. The risk of noninvasive treatment failure is higher in patients with severe oxygenation impairment. High-flow nasal oxygen (HFNO) is the most widely applied intervention, but noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) with different interfaces have also been used with varying success rates. Prone positioning and awake prone position have shown potential in avoiding endotracheal intubation, but careful monitoring is necessary, especially in patients with severe hypoxemia.

CURRENT OPINION IN CRITICAL CARE (2022)

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Article Medicine, General & Internal

Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19 The RECOVERY-RS Randomized Clinical Trial

Gavin D. Perkins et al.

Summary: Among patients with acute hypoxemic respiratory failure due to COVID-19, an initial strategy of CPAP significantly reduced the risk of tracheal intubation or mortality compared with conventional oxygen therapy, but there was no significant difference between an initial strategy of HFNO compared with conventional oxygen therapy. The study may have been underpowered for the comparison of HFNO vs conventional oxygen therapy, and early study termination and crossover among the groups should be considered when interpreting the findings.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Editorial Material Critical Care Medicine

Helmet noninvasive support in hypoxemic respiratory failure

Domenico Luca Grieco et al.

INTENSIVE CARE MEDICINE (2022)

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Editorial Material Critical Care Medicine

Noninvasive respiratory support in intensive care medicine

Nuttapol Rittayamai et al.

INTENSIVE CARE MEDICINE (2022)

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Article Medicine, General & Internal

Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure The HENIVOT Randomized Clinical Trial

Domenico Luca Grieco et al.

Summary: Among patients with COVID-19 and moderate to severe hypoxemia, treatment with helmet noninvasive ventilation compared with high-flow nasal oxygen did not result in a significant difference in the number of days free of respiratory support within 28 days.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Review Critical Care Medicine

Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS

Domenico Luca Grieco et al.

Summary: The role of non-invasive respiratory support in managing acute hypoxemic respiratory failure and acute respiratory distress syndrome is debated, with benefits of high-flow nasal oxygen or helmet interface positive end-expiratory pressure to reduce lung injury risk. Strict physiological monitoring during treatment is crucial to promptly detect the need for intubation.

INTENSIVE CARE MEDICINE (2021)

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Review Medicine, General & Internal