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Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review

Journal

CHEMISTRY & BIODIVERSITY
Volume 19, Issue 11, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.202200615

Keywords

Arctium lappa; secondary metabolites; extracts; biological functions; complement system; alternative treatment; popular medicinal herb

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Burdock, also known as Arctium lappa L., is a valuable plant in the biological and medical fields, containing phenolic compounds and terpenes with antioxidant, antimicrobial, antitumor, and anti-inflammatory properties. Burdock leaf extracts have shown the ability to modulate the complement system, which plays a crucial role in inflammatory diseases. Therefore, burdock may be a promising asset for researching and developing new therapies for inflammatory afflictions.
Arctium lappa L., also known as burdock, is an edible wild plant which has the ability to grow in distinct environments and is considered a weed in several parts of the world. This species has great value in the biological and medical fields with its major secondary components being phenolic compounds and terpenes, substances rich in desired biological activities as antioxidant, antimicrobial, antitumor and anti-inflammatory. In addition, burdock leaves extracts have shown a modulatory effect on the complement system, which plays an important role in the development of inflammatory diseases, with an inhibitory effect on all complement pathways. Thus, natural products with those relevant activities are promising agents for healthcare applications. Therefore, the species A. lappa may represent an interesting asset for researching and developing new therapies for inflammatory afflictions.

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