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ACS CHEMICAL BIOLOGY (2017)
Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis
Nilkamal Mahanta et al.
BIOCHEMISTRY (2017)
Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats
Hyunbin Lee et al.
BIOCHEMISTRY (2017)
Specificity of Subtilin-Mediated Activation of Histidine Kinase SpaK
Christoph Geiger et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2017)
The Role of Neutrophil Elastase Inhibitors in Lung Diseases
Eva Polverino et al.
CHEST (2017)
Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus
Konrad Viehrig et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors
Muhammad N. Ahmed et al.
ACS CHEMICAL BIOLOGY (2017)
Mining prokaryotes for antimicrobial compounds: from diversity to function
Vittorio Tracanna et al.
FEMS MICROBIOLOGY REVIEWS (2017)
YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function
Brandon J. Burkhart et al.
CHEMICAL REVIEWS (2017)
Pharmacological and pharmacokinetic properties of lanthipeptides undergoing clinical studies
Elvis Legala Ongey et al.
BIOTECHNOLOGY LETTERS (2017)
Bacterial Labionin-Containing Peptides and Sactibiotics: Unusual Types of Antimicrobial Peptides with Potential Use in Clinical Settings (a Review)
Marcus Livio Varella Coelho et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2017)
Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae
Mikhail Metelev et al.
ACS CHEMICAL BIOLOGY (2017)
An Engineered Allele of afsQ1 Facilitates the Discovery and Investigation of Cryptic Natural Products
Martin Daniel-Ivad et al.
ACS CHEMICAL BIOLOGY (2017)
Simplified AIP-II Peptidomimetics Are Potent Inhibitors of Staphylococcus aureus AgrC Quorum Sensing Receptors
Joseph Vasquez et al.
CHEMBIOCHEM (2017)
New Insights into Nisin's Antibacterial Mechanism Revealed by Binding Studies with Synthetic Lipid II Analogues
Peter't Hart et al.
BIOCHEMISTRY (2016)
Structure and activity relationships of the anti-Mycobacterium antibiotics resorcinomycin and pheganomycin
Yasushi Ogasawara et al.
JOURNAL OF ANTIBIOTICS (2016)
Leader Peptide-Free In Vitro Reconstitution of Microviridin Biosynthesis Enables Design of Synthetic Protease-Targeted Libraries
Emmanuel Reyna-Gonzalez et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
A TonB-Dependent Transporter Is Responsible for Methanobactin Uptake by Methylosinus trichosporium OB3b
Wenyu Gu et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Hit'em where it hurts: The growing and structurally diverse family of peptides that target lipid-II
Sabine F. Oppedijk et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)
Inhibition of Sonic Hedgehog Signaling Pathway by Thiazole Antibiotic Thiostrepton Attenuates the CD44+/CD24-Stem-Like Population and Sphere-Forming Capacity in Triple-Negative Breast Cancer
Na Yang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)
Color-Coded Super-Resolution Small-Molecule Imaging
Paolo Beuzer et al.
CHEMBIOCHEM (2016)
Insights into the Biosynthesis of Dehydroalanines in Goadsporin
Taro Ozaki et al.
CHEMBIOCHEM (2016)
Dual Chemical Modification of a Polytheonamide Mimic: Rational Design and Synthesis of Ion-Channel-Forming 48-mer Peptides with Potent Cytotoxicity
Atsushi Hayata et al.
CHEMISTRY-A EUROPEAN JOURNAL (2016)
The glycocins: in a class of their own
Gillian E. Norris et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)
The integrated stress response
Karolina Pakos-Zebrucka et al.
EMBO REPORTS (2016)
Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies
Christine K. Maurer et al.
FUTURE MEDICINAL CHEMISTRY (2016)
Propionibacterium acnes inhibits FOXM1 and induces cell cycle alterations in human primary prostate cells
Behnam Sayanjali et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2016)
Biomarkers for Radiation Pneumonitis Using Noninvasive Molecular Imaging
Meetha Medhora et al.
JOURNAL OF NUCLEAR MEDICINE (2016)
Rectified Proton Grotthuss Conduction Across a Long Water-Wire in the Test Nanotube of the Polytheonamide B Channel
Yuka Matsuki et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens
Marina Serebryakova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Copper-responsive gene expression in the methanotroph Methylosinus trichosporium OB3b
Grace E. Kenney et al.
METALLOMICS (2016)
Suppression of bacterial infection in rice by treatment with a sulfated peptide
Tong Wei et al.
MOLECULAR PLANT PATHOLOGY (2016)
Structural basis of outer membrane protein insertion by the BAM complex
Yinghong Gu et al.
NATURE (2016)
Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins
Long Han et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Detection of atherosclerotic plaques in ApoE-deficient mice using 99mTc-duramycin
Zhonglin Liu et al.
NUCLEAR MEDICINE AND BIOLOGY (2016)
Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus
Yftah Tal-Gan et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Total chemical synthesis of lassomycin and lassomycin-amide
S. Lear et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Synthesis and Bioactivity of Diastereomers of the Virulence Lanthipeptide Cytolysin
Subha Mukherjee et al.
ORGANIC LETTERS (2016)
Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection
Juan J. Quereda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Methanobactin transport machinery
Laura M. K. Dassama et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Genomic charting of ribosomally synthesized natural product chemical space facilitates targeted mining
Michael A. Skinnider et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM
Matthew G. Iadanza et al.
NATURE COMMUNICATIONS (2016)
Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins
Long Han et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Structure-Activity Analysis of Gram-positive Bacterium-producing Lasso Peptides with Anti-mycobacterial Activity
Junji Inokoshi et al.
SCIENTIFIC REPORTS (2016)
A Bioengineered Nisin Derivative, M21A, in Combination with Food Grade Additives Eradicates Biofilms of Listeria monocytogenes
Muireann K. Smith et al.
FRONTIERS IN MICROBIOLOGY (2016)
Plantazolicin Is an Ultranarrow-Spectrum Antibiotic That Targets the Bacillus anthracis Membrane
Katie J. Molohon et al.
ACS INFECTIOUS DISEASES (2016)
Monitoring Apoptosis of Breast Cancer Xenograft After Paclitaxel Treatment With 99mTc-Labeled Duramycin SPECT/CT
Rui Luo et al.
MOLECULAR IMAGING (2016)
Activation of band 3 mediates group A Streptococcus streptolysin S-based beta-haemolysis
Dustin L. Higashi et al.
NATURE MICROBIOLOGY (2016)
Bacterial membrane lipids: diversity in structures and pathways
Christian Sohlenkamp et al.
FEMS MICROBIOLOGY REVIEWS (2016)
Biosynthetic Pathway Connects Cryptic Ribosomally Synthesized Posttranslationally Modified Peptide Genes with Pyrroloquinoline Alkaloids
Peter A. Jordan et al.
CELL CHEMICAL BIOLOGY (2016)
Lasso Peptides: An Intriguing Class of Bacterial Natural Products
Julian D. Hegemann et al.
ACCOUNTS OF CHEMICAL RESEARCH (2015)
Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin
Yue Hao et al.
ACS CHEMICAL BIOLOGY (2015)
Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides
Yanyan Li et al.
ACS CHEMICAL BIOLOGY (2015)
Pinensins: The First Antifungal Lantibiotics
Kathrin I. Mohr et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
The Phosphoenolpyruvate:Sugar Phosphotransferase System Is Involved in Sensitivity to the Glucosylated Bacteriocin Sublancin
C. V. Garcia De Gonzalo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Enterocin F4-9, a Novel O-Linked Glycosylated Bacteriocin
Mohamed Abdelfattah Maky et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
Solution Structure of Acidocin B, a Circular Bacteriocin Produced by Lactobacillus acidophilus M46
Jeella Z. Acedo et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
Autoinduction Specificities of the Lantibiotics Subtilin and Nisin
Tobias Spiess et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2015)
Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium
Kohei Himeno et al.
BIOCHEMISTRY (2015)
Identification and analysis of the resorcinomycin biosynthetic gene cluster
Koichi Ooya et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2015)
Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family
Evelyn M. Molloy et al.
BMC MICROBIOLOGY (2015)
Increasing AIP Macrocycle Size Reveals Key Features of agr Activation in Staphylococcus aureus
Jeffrey G. Johnson et al.
CHEMBIOCHEM (2015)
Structure, Bioactivity, and Resistance Mechanism of Streptomonomicin, an Unusual Lasso Peptide from an Understudied Halophilic Actinomycete
Mikhail Metelev et al.
CHEMISTRY & BIOLOGY (2015)
Identification of Thiostrepton as a Novel Inhibitor for Psoriasis-like Inflammation Induced by TLR7-9
Chao-Yang Lai et al.
JOURNAL OF IMMUNOLOGY (2015)
Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid
Noah A. Bindman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Regulation of Bacterial Virulence by Csr (Rsm) Systems
Christopher A. Vakulskas et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2015)
Characterization of [99mTc]Duramycin as a SPECT Imaging Agent for Early Assessment of Tumor Apoptosis
Filipe Elvas et al.
MOLECULAR IMAGING AND BIOLOGY (2015)
Biological targets and mechanisms of action of natural products from marine cyanobacteria
Lilibeth A. Salvador-Reyes et al.
NATURAL PRODUCT REPORTS (2015)
The re-emergence of natural products for drug discovery in the genomics era
Alan L. Harvey et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
In vivo detection of hyperoxia-induced pulmonary endothelial cell death using 99mTc-Duramycin
Said H. Audi et al.
NUCLEAR MEDICINE AND BIOLOGY (2015)
The feasibility of imaging myocardial ischemic/reperfusion injury using 99mTc-labeled duramycin in a porcine model
Lei Wang et al.
NUCLEAR MEDICINE AND BIOLOGY (2015)
The Mycobacterium tuberculosis ClpP1P2 Protease Interacts Asymmetrically with Its ATPase Partners ClpX and ClpC1
Julia Leodolter et al.
PLOS ONE (2015)
Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses
Audrey Stephanie Richard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria
Elke Dittmann et al.
TRENDS IN MICROBIOLOGY (2015)
The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity
Liang Zhou et al.
FRONTIERS IN MICROBIOLOGY (2015)
RNA-binding proteins involved in post-transcriptional regulation in bacteria
Elke Van Assche et al.
FRONTIERS IN MICROBIOLOGY (2015)
Bioengineering of the model lantibiotic nisin
Des Field et al.
BIOENGINEERED (2015)
The rice immune receptor XA21 recognizes a tyrosine-sulfated protein from a Gram-negative bacterium
Rory N. Pruitt et al.
SCIENCE ADVANCES (2015)
A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin
Motoyoshi Noike et al.
NATURE CHEMICAL BIOLOGY (2015)
A Glycosylated, Labionin-Containing Lanthipeptide with Marked Antinociceptive Activity
Marianna Iorio et al.
ACS CHEMICAL BIOLOGY (2014)
Harnessing the Evolvability of Tricyclic Microviridins To Dissect Protease-Inhibitor Interactions
Annika R. Weiz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Functional Analysis of Environmental DNA-Derived Microviridins Provides New Insights into the Diversity of the Tricyclic Peptide Family
Douglas Gatte-Picchi et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)
Circular Bacteriocins: Biosynthesis and Mode of Action
Christina Gabrielsen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2014)
Type All lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action
Jie Zhang et al.
BIOCHEMICAL JOURNAL (2014)
Bactericidal activity of nukacin ISK-1: an alternative mode of action
Urmi Roy et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2014)
Intrigues and Intricacies of the Biosynthetic Pathways for the Enzymatic Quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ
Judith P. Klinman et al.
CHEMICAL REVIEWS (2014)
Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2
Ekaterina Gavrish et al.
CHEMISTRY & BIOLOGY (2014)
Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli
Dongchun Ni et al.
FASEB JOURNAL (2014)
Understanding polyspecificity within the substrate-binding cavity of the human multidrug resistance P-glycoprotein
Lorena Martinez et al.
FEBS JOURNAL (2014)
Bactericidal thurincin H causes unique morphological changes in Bacillus cereus F4552 without affecting membrane permeability
Gaoyan Wang et al.
FEMS MICROBIOLOGY LETTERS (2014)
RNA remodeling by bacterial global regulator CsrA promotes Rho-dependent transcription termination
Nara Figueroa-Bossi et al.
GENES & DEVELOPMENT (2014)
Mode of action and structure-activity relationship studies of geobacillin I
Neha Garg et al.
JOURNAL OF ANTIBIOTICS (2014)
The C-Terminal Part of Microcin B Is Crucial for DNA Gyrase Inhibition and Antibiotic Uptake by Sensitive Cells
Irina Shkundina et al.
JOURNAL OF BACTERIOLOGY (2014)
Amylocyclicin, a Novel Circular Bacteriocin Produced by Bacillus amyloliquefaciens FZB42
Romy Scholz et al.
JOURNAL OF BACTERIOLOGY (2014)
Identification of Ligand Specificity Determinants in Lantibiotic Bovicin HJ50 and the Receptor BovK, a Multitransmembrane Histidine Kinase*
Kunling Teng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions*
Daniela Muench et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Molecular Mechanism of Aminopropylation of Peptide-Nucleotide Antibiotic Microcin C
Alexey Kulikovsky et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Subcellular localization, interactions and dynamics of the phage-shock protein-like Lia response in Bacillus subtilis
Julia Dominguez-Escobar et al.
MOLECULAR MICROBIOLOGY (2014)
Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides
Indran Mathavan et al.
NATURE CHEMICAL BIOLOGY (2014)
The phzA2-G2 Transcript Exhibits Direct RsmA-Mediated Activation in Pseudomonas aeruginosa M18
Bin Ren et al.
PLOS ONE (2014)
Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system
Judith Habazettl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Refined structures of mouse P-glycoprotein
Jingzhi Li et al.
PROTEIN SCIENCE (2014)
Lateral Opening and Exit Pore Formation Are Required for BamA Function
Nicholas Noinaj et al.
STRUCTURE (2014)
Control of the cytotoxicity of dansylated polytheonamide mimic, an artificial peptide ion channel, by modification of the N-terminal structure
Hiroaki Itoh et al.
TETRAHEDRON LETTERS (2014)
Paradoxical One-ion Pore Behavior of the Long β-Helical Peptide of Marine Cytotoxic Polytheonamide B
Masayuki Iwamoto et al.
SCIENTIFIC REPORTS (2014)
Correlation between biofilm formation and gelE, esp, and agg genes in Enterococcus spp. clinical isolates
Renata O. Soares et al.
VIRULENCE (2014)
Functional characterization of WalRK: A two-component signal transduction system from Bacillus anthracis
Alisha Dhiman et al.
FEBS OPEN BIO (2014)
Large-Scale Purification, Characterization, and Spore Outgrowth Inhibitory Effect of Thurincin H, a Bacteriocin Produced by Bacillus thuringiensis SF361
Gaoyan Wang et al.
PROBIOTICS AND ANTIMICROBIAL PROTEINS (2014)
Discovering new bioactive molecules from microbial sources
Paolo Monciardini et al.
MICROBIAL BIOTECHNOLOGY (2014)
Peptide pheromone signaling in Streptococcus and Enterococcus
Laura C. Cook et al.
FEMS MICROBIOLOGY REVIEWS (2014)
Role of SbmA in the Uptake of Peptide Nucleic Acid (PNA)-Peptide Conjugates in E-coli
Anubrata Ghosal et al.
ACS CHEMICAL BIOLOGY (2013)
Bacteriocin AS-48 binding to model membranes and pore formation as revealed by coarse-grained simulations
Victor L. Cruz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Genome Mining Expands the Chemical Diversity of the Cyanobactin Family to Include Highly Modified Linear Peptides
Niina Leikoski et al.
CHEMISTRY & BIOLOGY (2013)
Methanobactin and MmoD work in concert to act as the 'copper-switch' in methanotrophs
Jeremy D. Semrau et al.
ENVIRONMENTAL MICROBIOLOGY (2013)
Microcin E492 Amyloid Formation Is Retarded by Posttranslational Modification
Andres Marcoleta et al.
JOURNAL OF BACTERIOLOGY (2013)
Whole-Body Imaging of High-Dose Ionizing Irradiation-Induced Tissue Injuries Using 99mTc-Duramycin
Steven E. Johnson et al.
JOURNAL OF NUCLEAR MEDICINE (2013)
Structural Characterization of Native Autoinducing Peptides and Abiotic Analogues Reveals Key Features Essential for Activation and Inhibition of an AgrC Quorum Sensing Receptor in Staphylococcus aureus
Yftah Tal-Gan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Highly Potent Inhibitors of Quorum Sensing in Staphylococcus aureus Revealed Through a Systematic Synthetic Study of the Group-III Autoinducing Peptide
Yftah Tal-Gan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
A General Method for Fluorescent Labeling of the N-Termini of Lanthipeptides and Its Application to Visualize their Cellular Localization
Noah A. Bindman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
CsrA activates flhDC expression by protecting flhDC mRNA from RNase E-mediated cleavage
Alexander V. Yakhnin et al.
MOLECULAR MICROBIOLOGY (2013)
Recent Advances in Dissecting Stress-Regulatory Crosstalk in Rice
Rita Sharma et al.
MOLECULAR PLANT (2013)
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
Paul G. Arnison et al.
NATURAL PRODUCT REPORTS (2013)
Structural insight into the biogenesis of β-barrel membrane proteins
Nicholas Noinaj et al.
NATURE (2013)
The sequence of the enterococcal cytolysin imparts unusual lanthionine stereochemistry
Weixin Tang et al.
NATURE CHEMICAL BIOLOGY (2013)
Interactions of the intact FsrC membrane histidine kinase with the tricyclic peptide inhibitor siamycin I revealed through synchrotron radiation circular dichroism
Mary K. Phillips-Jones et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2013)
The XA21 binding protein XB25 is required for maintaining XA21-mediated disease resistance
Yingnan Jiang et al.
PLANT JOURNAL (2013)
Saturation Mutagenesis of Lysine 12 Leads to the Identification of Derivatives of Nisin A with Enhanced Antimicrobial Activity
Evelyn M. Molloy et al.
PLOS ONE (2013)
Fragments of the Bacterial Toxin Microcin B17 as Gyrase Poisons
Frederic Collin et al.
PLOS ONE (2013)
The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications
Geoffrey Ferir et al.
PLOS ONE (2013)
Enhanced Production, Purification, Characterization and Mechanism of Action of Salivaricin 9 Lantibiotic Produced by Streptococcus salivarius NU10
Abdelahhad Barbour et al.
PLOS ONE (2013)
Intensive Mutagenesis of the Nisin Hinge Leads to the Rational Design of Enhanced Derivatives
Brian Healy et al.
PLOS ONE (2013)
Precursor-directed generation of amidine containing ammosamide analogs: ammosamides E-P
Ende Pan et al.
CHEMICAL SCIENCE (2013)
Structural Permutation of Potent Cytotoxin, Polytheonamide B: Discovery of Cytotoxic Peptide with Altered Activity
Hiroaki Itoh et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Structure, Function, and Biology of the Enterococcus faecalis Cytolysin
Daria Van Tyne et al.
TOXINS (2013)
Safety, Formulation and In Vitro Antiviral Activity of the Antimicrobial Peptide Subtilosin Against Herpes Simplex Virus Type 1
Nicolas I. Torres et al.
PROBIOTICS AND ANTIMICROBIAL PROTEINS (2013)
Non-proteinogenic Amino Acids in Lacticin 481 Analogues Result in More Potent Inhibition of Peptidoglycan Transglycosylation
Patrick J. Knerr et al.
ACS CHEMICAL BIOLOGY (2012)
Biosynthesis of the Class III Lantipeptide Catenulipeptin
Huan Wang et al.
ACS CHEMICAL BIOLOGY (2012)
Discovery, Biosynthesis, and Engineering of Lantipeptides
Patrick J. Knerr et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Apicoplast-Targeting Antibacterials Inhibit the Growth of Babesia Parasites
Mahmoud AbouLaila et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Bacterial Resistance to Antisense Peptide Phosphorodiamidate Morpholino Oligomers
Susan E. Puckett et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
The Maltose ABC Transporter in Lactococcus lactis Facilitates High-Level Sensitivity to the Circular Bacteriocin Garvicin ML
Christina Gabrielsen et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Fratricide Is Essential for Efficient Gene Transfer between Pneumococci in Biofilms
Hua Wei et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2012)
Interactions of the intact FsrC membrane histidine kinase with its pheromone ligand GBAP revealed through synchrotron radiation circular dichroism
Simon G. Patching et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Codon Randomization for Rapid Exploration of Chemical Space in Thiopeptide Antibiotic Variants
Travis S. Young et al.
CHEMISTRY & BIOLOGY (2012)
Selective Modification of the N-Terminal Structure of Polytheonamide B Significantly Changes its Cytotoxicity and Activity as an Ion Channel
Naoki Shinohara et al.
CHEMMEDCHEM (2012)
Lacticin 3147-Biosynthesis, Molecular Analysis, Immunity, Bioengineering and Applications
Srinivas Suda et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2012)
Microcin C: biosynthesis and mechanisms of bacterial resistance
Konstantin Severinov et al.
FUTURE MICROBIOLOGY (2012)
Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus
Nina M. Haste et al.
JOURNAL OF ANTIBIOTICS (2012)
Synthetic Lethality of the lytE cwlO Genotype in Bacillus subtilis Is Caused by Lack of D,L-Endopeptidase Activity at the Lateral Cell Wall
Masayuki Hashimoto et al.
JOURNAL OF BACTERIOLOGY (2012)
Microcin Amyloid Fibrils A Are Reservoir of Toxic Oligomeric Species
Mohammad Shahnawaz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Design, Synthesis, and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors of Quinone Reductase 2
P. V. Narasimha Reddy et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Origin and Variation of Tunicate Secondary Metabolites
Eric W. Schmidt et al.
JOURNAL OF NATURAL PRODUCTS (2012)
An Engineered Lantibiotic Synthetase That Does Not Require a Leader Peptide on Its Substrate
Trent J. Oman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Chemical Synthesis and Biological Activity of Analogues of the Lantibiotic Epilancin 15X
Patrick J. Knerr et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Design, Synthesis and Functional Analysis of Dansylated Polytheonamide Mimic: An Artificial Peptide Ion Channel
Hiroaki Itoh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Ring A of Nukacin ISK-1: A Lipid II-Binding Motif for Type-A(II) Lantibiotic
Mohammad R. Islam et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Multi-tier regulation of the streptomycete morphogenetic peptide SapB
Alisa A. Gaskell et al.
MOLECULAR MICROBIOLOGY (2012)
The species-specific mode of action of the antimicrobial peptide subtilosin against Listeria monocytogenes Scott A
S. van Kuijk et al.
LETTERS IN APPLIED MICROBIOLOGY (2012)
Lasso peptides: structure, function, biosynthesis, and engineering
Mikhail O. Maksimov et al.
NATURAL PRODUCT REPORTS (2012)
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
N. M. Archin et al.
NATURE (2012)
YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations
Kyle L. Dunbar et al.
NATURE CHEMICAL BIOLOGY (2012)
Bioengineered Nisin A Derivatives with Enhanced Activity against Both Gram Positive and Gram Negative Pathogens
Des Field et al.
PLOS ONE (2012)
Initiation factor 2, tRNA, and 50S subunits cooperatively stabilize mRNAs on the ribosome during initiation
Tomoaki Masuda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Variations in methanobactin structure influences copper utilization by methane-oxidizing bacteria
Abdelnasser El Ghazouani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Lantibiotics from Geobacillus thermodenitrificans
Neha Garg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics
Katie J. Molohon et al.
ACS CHEMICAL BIOLOGY (2011)
Mechanism of Inhibition of Bacillus anthracis Spore Outgrowth by the Lantibiotic Nisin
Ian M. Gut et al.
ACS CHEMICAL BIOLOGY (2011)
Lantibiotics as probes for phosphatidylethanolamine
Ming Zhao
AMINO ACIDS (2011)
Autoregulation of Lantibiotic Bovicin HJ50 Biosynthesis by the BovK-BovR Two-Component Signal Transduction System in Streptococcus bovis HJ50
Jianqiang Ni et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Characterization of Garvicin ML, a Novel Circular Bacteriocin Produced by Lactococcus garvieae DCC43, Isolated from Mallard Ducks (Anas platyrhynchos)
Juan Borrero et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Identification and Characterization of Leucocyclicin Q, a Novel Cyclic Bacteriocin Produced by Leuconostoc mesenteroides TK41401
Yoshimitsu Masuda et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Redox-active tyrosine residue in the microcin J25 molecule
Miriam C. Chalon et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Ruminococcin C, a new anti-Clostridium perfringens bacteriocin produced in the gut by the commensal bacterium Ruminococcus gnavus E1
E. H. Crost et al.
BIOCHIMIE (2011)
Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials
Gaston H. M. Vondenhoff et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners
Daniel H. Haft
BMC GENOMICS (2011)
Proteasome inhibitory activity of thiazole antibiotics
Bulbul Pandit et al.
CANCER BIOLOGY & THERAPY (2011)
Peptide Signaling in the Staphylococci
Matthew Thoendel et al.
CHEMICAL REVIEWS (2011)
Cysteine S-glycosylation, a new post-translational modification found in glycopeptide bacteriocins
Judith Stepper et al.
FEBS LETTERS (2011)
Anti-HIV siamycin I directly inhibits autophosphorylation activity of the bacterial FsrC quorum sensor and other ATP-dependent enzyme activities
Pikyee Ma et al.
FEBS LETTERS (2011)
Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation
Natalie Steck et al.
GASTROENTEROLOGY (2011)
Plantazolicin, a Novel Microcin B17/Streptolysin S-Like Natural Product from Bacillus amyloliquefaciens FZB42
Romy Scholz et al.
JOURNAL OF BACTERIOLOGY (2011)
Enterococcus faecalis Virulence Regulator FsrA Binding to Target Promoters
Maria Florencia Del Papa et al.
JOURNAL OF BACTERIOLOGY (2011)
Characterization of Peptide Chain Length and Constituency Requirements for YejABEF-Mediated Uptake of Microcin C Analogues
Gaston H. M. Vondenhoff et al.
JOURNAL OF BACTERIOLOGY (2011)
Streptolysin S Contributes to Group A Streptococcal Translocation across an Epithelial Barrier
Tomoko Sumitomo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Dual Pathways for Copper Uptake by Methanotrophic Bacteria
Ramakrishnan Balasubramanian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The Antibacterial Threaded-lasso Peptide Capistruin Inhibits Bacterial RNA Polymerase
Konstantin Kuznedelov et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Haloduracin α Binds the Peptidoglycan Precursor Lipid II with 2:1 Stoichiometry
Trent J. Oman et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Discovery and Assembly-Line Biosynthesis of the Lymphostin Pyrroloquinoline Alkaloid Family of mTOR Inhibitors in Salinispora Bacteria
Akimasa Miyanaga et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
The 3D Structure of Thuricin CD, a Two-Component Bacteriocin with Cysteine Sulfur to α-Carbon Cross-links
Clarissa S. Sit et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Nine Post-translational Modifications during the Biosynthesis of Cinnamycin
Ayse Oekesli et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Transcript-level responses of Plasmodium falciparum to thiostrepton
Sarah J. Tarr et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2011)
Sublancin is not a lantibiotic but an S-linked glycopeptide
Trent J. Oman et al.
NATURE CHEMICAL BIOLOGY (2011)
The transcription factor FOXM1 is a cellular target of the natural product thiostrepton
Nagaratna S. Hegde et al.
NATURE CHEMISTRY (2011)
Plantazolicin A and B: Structure Elucidation of Ribosomally Synthesized Thiazole/Oxazole Peptides from Bacillus amyloliquefaciens FZB42
Bahar Kalyon et al.
ORGANIC LETTERS (2011)
Variation in Tropical Reef Symbiont Metagenomes Defined by Secondary Metabolism
Mohamed S. Donia et al.
PLOS ONE (2011)
Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon
Mary C. Rea et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Genetic dissection of the biotic stress response using a genome-scale gene network for rice
Insuk Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis
Mohamed S. Donia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Towards Establishment of a Rice Stress Response Interactome
Young-Su Seo et al.
PLOS GENETICS (2011)
High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism
Jennifer E. Griffin et al.
PLOS PATHOGENS (2011)
Chemical and Metabolic Aspects of Antimetabolite Toxins Produced by Pseudomonas syringae Pathovars
Eva Arrebola et al.
TOXINS (2011)
Elucidation of the Molecular Mechanisms of Action of the Natural Antimicrobial Peptide Subtilosin Against the Bacterial Vaginosis-associated Pathogen Gardnerella vaginalis
Katia Sutyak Noll et al.
PROBIOTICS AND ANTIMICROBIAL PROTEINS (2011)
Cannibalism: a social behavior in sporulating Bacillus subtilis
Jose Eduardo Gonzalez-Pastor
FEMS MICROBIOLOGY REVIEWS (2011)
Labyrinthopeptins: A New Class of Carbacyclic Lantibiotics
Kathrin Meindl et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Antiplasmodial Thiostrepton Derivatives: Proteasome Inhibitors with a Dual Mode of Action
Sebastian Schoof et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
TonB-Dependent Transporters: Regulation, Structure, and Function
Nicholas Noinaj et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010 (2010)
Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47
Gaelle Vassiliadis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Effect of duramycin on chloride transport and intracellular calcium concentration in cystic fibrosis and non-cystic fibrosis epithelia
Igor Oliynyk et al.
APMIS (2010)
Exploiting the Natural Diversity of Microviridin Gene Clusters for Discovery of Novel Tricyclic Depsipeptides
Nadine Ziemert et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2010)
Cyanobactins-ribosomal cyclic peptides produced by cyanobacteria
Kaarina Sivonen et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
A Comparison of Methanobactins from Methylosinus trichosporium OB3b and Methylocystis Strain SB2 Predicts Methanobactins Are Synthesized from Diverse Peptide Precursors Modified To Create a Common Core for Binding and Reducing Copper Ions
Benjamin D. Krentz et al.
BIOCHEMISTRY (2010)
Bottromycin derivatives: Efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities
Yutaka Kobayashi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Thiazole antibiotics against breast cancer
Marianna Halasi et al.
CELL CYCLE (2010)
Elucidation of XA21-mediated innate immunity
Chang-Jin Park et al.
CELLULAR MICROBIOLOGY (2010)
Effect of Bioengineering Lacticin 3147 Lanthionine Bridges on Specific Activity and Resistance to Heat and Protease's
Srinivas Suda et al.
CHEMISTRY & BIOLOGY (2010)
High-Resolution Crystal Structure of a Lasso Peptide
Herbert Nar et al.
CHEMMEDCHEM (2010)
Enhancements of screening collections to address areas of unmet medical need: an industry perspective
David H. Drewry et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2010)
The glucagon receptor antagonist BI-32169 constitutes a new class of lasso peptides
Thomas A. Knappe et al.
FEBS LETTERS (2010)
A cytotoxic peptide from a marine sponge exhibits ion channel activity through vectorial-insertion into the membrane
Masayuki Iwamoto et al.
FEBS LETTERS (2010)
Gelatinase Contributes to the Pathogenesis of Endocarditis Caused by Enterococcus faecalis
Lance R. Thurlow et al.
INFECTION AND IMMUNITY (2010)
Microcin J25 triggers cytochrome c release through irreversible damage of mitochondrial proteins and lipids
Maria V. Niklison-Chirou et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
A Novel Pheromone Quorum-Sensing System Controls the Development of Natural Competence in Streptococcus thermophilus and Streptococcus salivarius
Laetitia Fontaine et al.
JOURNAL OF BACTERIOLOGY (2010)
In-Depth Profiling of the LiaR Response of Bacillus subtilis
Diana Wolf et al.
JOURNAL OF BACTERIOLOGY (2010)
Clostridiolysin S, a Post-translationally Modified Biotoxin from Clostridium botulinum
David J. Gonzalez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Structure-activity relationship of marinostatin, a serine protease inhibitor isolated from a marine organism
Misako Taichi et al.
JOURNAL OF PEPTIDE SCIENCE (2010)
Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge
Toshiyuki Hamada et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA
Yasuhiko Irie et al.
MOLECULAR MICROBIOLOGY (2010)
Follow the leader: the use of leader peptides to guide natural product biosynthesis
Trent J. Oman et al.
NATURE CHEMICAL BIOLOGY (2010)
Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis
Wei-Ting Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile
Mary C. Rea et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The polypeptide core of Microcin E492 stably associates with the mannose permease and interferes with mannose metabolism
Sylvain Bieler et al.
RESEARCH IN MICROBIOLOGY (2010)
Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147
Lucy H. Deegan et al.
MICROBIAL BIOTECHNOLOGY (2010)
Antibacterial Activity of Subtilosin Alone and Combined with Curcumin, Poly-Lysine and Zinc Lactate Against Listeria monocytogenes Strains
Tahar Amrouche et al.
PROBIOTICS AND ANTIMICROBIAL PROTEINS (2010)
Insights into the Mode of Action of the Two-Peptide Lantibiotic Haloduracin
Trent J. Oman et al.
ACS CHEMICAL BIOLOGY (2009)
Ammosamides A and B Target Myosin
Chambers C. Hughes et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
The Ammosamides: Structures of Cell Cycle Modulators from a Marine-Derived Streptomyces Species
Chambers C. Hughes et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Structure Determination and Total Synthesis of Bottromycin A(2): A Potent Antibiotic against MRSA and VRE
Hiroyuki Shimamura et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
The Large Mechanosensitive Channel MscL Determines Bacterial Susceptibility to the Bacteriocin Sublancin 168
Thijs R. H. M. Kouwen et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Nukacin ISK-1, a Bacteriostatic Lantibiotic
Sikder M. Asaduzzaman et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Influence of Ca2+ Ions on the Activity of Lantibiotics Containing a Mersacidin-Like Lipid II Binding Motif
T. Boettiger et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
Identification and Characterization of Lactocyclicin Q, a Novel Cyclic Bacteriocin Produced by Lactococcus sp Strain QU 12
Naruhiko Sawa et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
The circular bacteriocin, carnocyclin A, forms anion-selective channels in lipid bilayers
Xiandi Gong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Proton motive force dissipation precludes interaction of microcin J25 with RNA polymerase, but enhances reactive oxygen species overproduction
Fernando G. Dupuy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity
Masato Iwatsuki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Biosynthesis of Indolocarbazole and Goadsporin, Two Different Heterocyclic Antibiotics Produced by Actinomycetes
Hiroyasu Onaka
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2009)
Streptococcus pyogenes induces oncosis in macrophages through the activation of an inflammatory programmed cell death pathway
Oliver Goldmann et al.
CELLULAR MICROBIOLOGY (2009)
A Fluorescent Probe for the 70S-Ribosomal GTPase-Associated Center
Sebastian Schoof et al.
CHEMBIOCHEM (2009)
Lantibiotics: Mode of Action, Biosynthesis and Bioengineering
G. Bierbaum et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2009)
Tyrosine 9 is the key amino acid in microcin J25 superoxide overproduction
Miriam C. Chalon et al.
FEMS MICROBIOLOGY LETTERS (2009)
Biosynthesis and transcriptional analysis of thurincin H, a tandem repeated bacteriocin genetic locus, produced by Bacillus thuringiensis SF361
Hyungjae Lee et al.
FEMS MICROBIOLOGY LETTERS (2009)
Structure-Activity Relationship of Gelatinase Biosynthesis-Activating Pheromone of Enterococcus faecalis
Kenzo Nishiguchi et al.
JOURNAL OF BACTERIOLOGY (2009)
Isolation of a Variant of Subtilosin A with Hemolytic Activity
Tai Huang et al.
JOURNAL OF BACTERIOLOGY (2009)
Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases
Pieter Van de Vijver et al.
JOURNAL OF BACTERIOLOGY (2009)
Maturation of the Translation Inhibitor Microcin C
Anastasia Metlitskaya et al.
JOURNAL OF BACTERIOLOGY (2009)
The Three-dimensional Structure of Carnocyclin A Reveals That Many Circular Bacteriocins Share a Common Structural Motif
Leah A. Martin-Visscher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structural and Functional Dissection of the Heterocyclic Peptide Cytotoxin Streptolysin S
Douglas A. Mitchell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Lantibiotics: Diverse activities and unique modes of action
Sikder M. Asaduzzaman et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2009)
In Vitro Mutasynthesis of Lantibiotic Analogues Containing Nonproteinogenic Amino Acids
Matthew R. Levengood et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor Tu
Rowan P. Morris et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Evaluation of essential and variable residues of nukacin ISK-1 by NNK scanning
Mohammad R. Islam et al.
MOLECULAR MICROBIOLOGY (2009)
Mechanisms and Evolution of Control Logic in Prokaryotic Transcriptional Regulation
Sacha A. F. T. van Hijum et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2009)
Synthesis and Biological Activity of Oxa-Lacticin A2, a Lantibiotic Analogue with Sulfur Replaced by Oxygen
Hongqiang Liu et al.
ORGANIC LETTERS (2009)
Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells
Uppoor G. Bhat et al.
PLOS ONE (2009)
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Stephen G. Aller et al.
SCIENCE (2009)
Generation of multiple cell types in Bacillus subtilis
Daniel Lopez et al.
FEMS MICROBIOLOGY REVIEWS (2009)
Solid-Supported Synthesis and Biological Evaluation of the Lantibiotic Peptide Bis(desmethyl) Lacticin 3147 A2
Vijaya R. Pattabiraman et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2
Maria Pranting et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Inhibition of Bacillus anthracis Spore Outgrowth by Nisin
Ian M. Gut et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Isolation and characterization of carnocyclin A, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307
Leah A. Martin-Visscher et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2008)
Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492 C-terminus: Linkage of ribosomal and nonribosomal peptides to form Trojan Horse antibiotics
Elizabeth M. Nolan et al.
BIOCHEMISTRY (2008)
Elucidation of the antimicrobial mechanism of mutacin 1140
Leif Smith et al.
BIOCHEMISTRY (2008)
Spermicidal bacteriocins: Lacticin 3147 and subtilosin A
Lara Silkin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Chemical structure of posttranslational modification with a Farnesyl group on tryptophan
Masahiro Okada et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)
Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer
Nuran Bektas et al.
BMC CANCER (2008)
Novel anticancer compounds induce apoptosis in melanoma cells
Uppoor G. Bhat et al.
CELL CYCLE (2008)
Structure-Activity Relationship Studies of the Two-Component Lantibiotic Haloduracin
Lisa E. Cooper et al.
CHEMISTRY & BIOLOGY (2008)
Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens
Franca Castiglione et al.
CHEMISTRY & BIOLOGY (2008)
Copper methanobactin: a molecule whose time has come
Ramakrishnan Balasubramanian et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Microcin J25 induces the opening of the mitochondrial transition pore and cytochrome c release through superoxide generation
Maria Niklison Chirou et al.
FEBS JOURNAL (2008)
Eschetichia coli peptidase A, B, or N can process translation inhibitor microcin C
Teyrnur Kazakov et al.
JOURNAL OF BACTERIOLOGY (2008)
Systematic structure-activity analysis of microcin J25
Olga Pavlova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Identification of ligand specificity determinants in AgrC, the Staphylococcus aureus quorum-sensing receptor
Edward Geisinger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Differential recognition of Staphylococcus aureus quorum-sensing signals depends on both extracellular loops 1 and 2 of the transmembrane sensor AgrC
Rasmus O. Jensen et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Mollamides B and C, cyclic hexapeptides from the Indonesian tunicate Didemnum molle
Marwa S. Donia et al.
JOURNAL OF NATURAL PRODUCTS (2008)
99mTc-labeled duramycin as a novel phosphatidylethanolamine-binding molecular probe
Ming Zhao et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264
Thomas A. Knappe et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Mapping the binding site of thiopeptide antibiotics by proximity-induced covalent capture
Sascha Baumann et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
NMR, mass spectrometry and chemical evidence reveal a different chemical structure for methanobactin that contains oxazolone rings
Lee A. Behling et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression
Jimmy M-M. Kwok et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Translational regulation via L11: Molecular switches on the ribosome turned on and off by thiostrepton and micrococcin
Joerg M. Harms et al.
MOLECULAR CELL (2008)
The generation of nisin variants with enhanced activity against specific Gram-positive pathogens
Des Field et al.
MOLECULAR MICROBIOLOGY (2008)
OsWRKY62 is a negative regulator of basal and Xa21-mediated defense against Xanthomonas oryzae pv. oryzae in rice
Ying Peng et al.
MOLECULAR PLANT (2008)
Effects of duramycin on cardiac voltage-gated ion channels
Eva Zebedin et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
Pulmonary pharmacokinetics and safety of nebulized duramycin in healthy male volunteers
Ilka Steiner et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
Discovery of a widely distributed toxin biosynthetic gene cluster
Shaun W. Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Rice XB15, a protein phosphatase 2C, negatively regulates cell death and XA21-mediated innate immunity
Chang-Jin Park et al.
PLOS BIOLOGY (2008)
Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes
Paul D. Cotter et al.
PLOS PATHOGENS (2008)
Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin
J. Lubelski et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Thiostrepton inhibition of tRNA delivery to the ribosome
Ruben L. Gonzalez et al.
RNA (2007)
The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system
Bronwyn G. Butcher et al.
JOURNAL OF BACTERIOLOGY (2007)
Biosynthetic tailoring of microcin e492m: Post-translational modification affords an antibacterial siderophore-peptide conjugate
Elizabeth M. Nolan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Tyrosine-sulfated glycopeptide involved in cellular proliferation and expansion in Arabidopsis
Yukari Amano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Escherichia coli yej transporter is required for the uptake of translation inhibitor microcin C
Maria Novikova et al.
JOURNAL OF BACTERIOLOGY (2007)
The emerging roles of forkhead box (Fox) proteins in cancer
Stephen S. Myatt et al.
NATURE REVIEWS CANCER (2007)
Expanding role of lipid II as a target for lantibiotics
Nathaniel I. Martin et al.
FUTURE MICROBIOLOGY (2007)
Role of the Escherichia coli SbmA in the antimicrobial activity of proline-rich peptides
Maura Mattiuzzo et al.
MOLECULAR MICROBIOLOGY (2007)
Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation
Rick Rink et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Novel propeptin analog, propeptin-2, missing two amino acid residues from the propeptin C-terminus loses antibiotic potency
Ken-ichi Kimura et al.
JOURNAL OF ANTIBIOTICS (2007)
A role for type I signal peptidase in Staphylococcus aureus quorum sensing
Jeffrey S. Kavanaugh et al.
MOLECULAR MICROBIOLOGY (2007)
DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis
Daniel T. Verhamme et al.
MOLECULAR MICROBIOLOGY (2007)
Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171
Masato Iwatsuki et al.
JOURNAL OF ANTIBIOTICS (2007)
Uberolysin:: a novel cyclic bacteriocin produced by Streptococcus uberis
Ruth E. Wirawan et al.
MICROBIOLOGY-SGM (2007)
Inhalation of Moli1901 in patients with cystic fibrosis
Hartmut Grasemann et al.
CHEST (2007)
Relatedness between the two-component lantibiotics lacticin 3147 and staphylococcin C55 based on structure, genetics and biological activity
Eileen B. O'Connor et al.
BMC MICROBIOLOGY (2007)
The effects of anti-bacterials on the malaria parasite Plasmodium falciparum
Christopher Dean Goodman et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2007)
Structure-activity relationship studies on quorum sensing ComXRO-E-2 pheromone
Masahiro Okada et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Amino acid residues required for maturation, cell uptake, and processing of translation inhibitor microcin C
Teymur Kazakov et al.
JOURNAL OF BACTERIOLOGY (2007)
Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis
Jiro Nakayama et al.
JOURNAL OF BACTERIOLOGY (2007)
Identification of a novel two-peptide lantibiotic, Haloduracin, produced by the alkaliphile Bacillus halodurans C-125
Elaine M. Lawton et al.
FEMS MICROBIOLOGY LETTERS (2007)
Marine metabolites: metal binding and metal complexes of azole-based cyclic peptides of marine origin
Anna Bertram et al.
NATURAL PRODUCT REPORTS (2007)
L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy
Hendrik R. A. Jonker et al.
NUCLEIC ACIDS RESEARCH (2007)
The biology of lantibiotics from the lacticin 481 group is coming of age
Alain Dufour et al.
FEMS MICROBIOLOGY REVIEWS (2007)
A system for the random mutagenesis of the two-peptide lantibiotic lacticin 3147: Analysis of mutants producing reduced antibacterial activities
Des Field et al.
JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY (2007)
Microcins, gene-encoded antibacterial peptides from enterobacteria
Sophie Duquesne et al.
NATURAL PRODUCT REPORTS (2007)
Cannibalism and fratricide: mechanisms and raisons d'etre
Jean-Pierre Claverys et al.
NATURE REVIEWS MICROBIOLOGY (2007)
An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer
Masaru Hashimoto et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Rice XA21 binding protein 3 is a ubiquitin ligase required for full Xa21-mediated disease resistance
Yong-Sheng Wang et al.
PLANT CELL (2006)
Revised model for Enterococcus faecalis fsr quorum-sensing system:: the small oven readina frame fsrD encodes the gelatinase biosynthesis-activating pheromone propeptide corresponding to staphylococcal AgrD
Jiro Nakayama et al.
JOURNAL OF BACTERIOLOGY (2006)
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic
Amanda L. McClerren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The lantibiotic mersacidin is an autoinducing peptide
Stephanie Schmitz et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design
Paul D. Cotter et al.
MOLECULAR MICROBIOLOGY (2006)
Bactericidal activity of both secreted and nonsecreted microcin e492 requires the mannose permease
Sylvain Bieler et al.
JOURNAL OF BACTERIOLOGY (2006)
Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1
Senthil K. Radhakrishnan et al.
CANCER RESEARCH (2006)
Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase
Champak Chatterjee et al.
CHEMISTRY & BIOLOGY (2006)
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II
Hester E. Hasper et al.
SCIENCE (2006)
Interaction of the antimicrobial peptide pheromone Plantaricin A with model membranes: Implications for a novel mechanism of action
Hongxla Zhao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Lysine-oriented charges trigger the membrane binding and activity of nukacin ISK-1
Sikder M. Asaduzzaman et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
New microviridins from a water bloom of the cyanobacterium Microcystis aeruginosa
Vered Reshef et al.
TETRAHEDRON (2006)
The mode of action of the lantibiotic lacticin 3147 -: a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II
Imke Wiedemann et al.
MOLECULAR MICROBIOLOGY (2006)
Interactions between Streptomyces coelicolor and Bacillus subtilis:: Role of surfactants in raising aerial structures
Paul D. Straight et al.
JOURNAL OF BACTERIOLOGY (2006)
Regulation of LiaRS-dependent gene expression in Bacillus subtilis:: Identification of inhibitor proteins, regulator binding sites, and target genes of a conserved cell envelope stress-sensing two-component system
Sina Jordan et al.
JOURNAL OF BACTERIOLOGY (2006)
Aspartyl-tRNA synthetase is the target of peptide nucleotide antibiotic Microcin C
Anastasia Metlitskaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu
Andrea Parmeggiani et al.
BIOCHEMISTRY (2006)
Microcin J25 uptake:: His5 of the MccJ25 lariat ring is involved in interaction with the inner membrane MccJ25 transporter protein SbmA
RE de Cristóbal et al.
JOURNAL OF BACTERIOLOGY (2006)
Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies
RR Bonelli et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Lipid II-based antimicrobial activity of the lantibiotic plantaricin C
I Wiedemann et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Parasitism of iron-siderophore receptors of Escherichia coli by the siderophore-peptide microcin E492m and its unmodified counterpart
Delphine Destoumieux-Garzon et al.
BIOMETALS (2006)
Lipid II as a target for antibiotics
E Breukink et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
The autophosphorylated Ser686, Thr688, and Ser689 residues in the intracellular juxtamembrane domain of XA21 are implicated in stability control of rice receptor-like kinase
WH Xu et al.
PLANT JOURNAL (2006)
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin
CD Ellermeier et al.
CELL (2006)
Spectral, kinetic, and thermodynamic properties of Cu(I) and Cu(II) binding by methanobactin from Methylosinus trichosporium OB3b
DW Choi et al.
BIOCHEMISTRY (2006)
Production of the lantibiotic salivaricin A and its variants by oral streptococci and use of a specific induction assay to detect their presence in human saliva
PA Wescombe et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2006)
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice
TV Kalin et al.
CANCER RESEARCH (2006)
Xanthomonas oryzae pathovars: model pathogens of a model crop
David O. Nino-Liu et al.
MOLECULAR PLANT PATHOLOGY (2006)
Thioviridamide, a novel apoptosis inducer in transformed cells from Streptomyces olivoviridis
Y Hayakawa et al.
JOURNAL OF ANTIBIOTICS (2006)
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147
PD Cotter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Cloning and characterization of the goadsporin biosynthetic gene cluster from Streptomyces sp TP-A0584
H Onaka et al.
MICROBIOLOGY-SGM (2005)
SapT, a lanthionine-containing peptide involved in aerial hyphae formation in the streptomycetes
S Kodani et al.
MOLECULAR MICROBIOLOGY (2005)
Antibiotic susceptibility of mammalian mitochondrial translation
L Zhang et al.
FEBS LETTERS (2005)
Discovery of a biologically active thiostrepton fragment
KC Nicolaou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Membrane permeabilization, orientation, and antimicrobial mechanism of subtilosin A
S Thennarasu et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2005)
Effect of methanobactin on the activity and electron paramagnetic resonance spectra of the membrane-associated methane monooxygenase in Methylococcus capsulatus Bath
DW Choi et al.
MICROBIOLOGY-SGM (2005)
Domain reorientation and induced fit upon RNA binding:: Solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima
S Ilin et al.
CHEMBIOCHEM (2005)
Interactions of the N-terminal domain of ribosomal protein L11 with thiostrepton and rRNA
SL Bausch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The iron-siderophore transporter FhuA is the receptor for the antimicrobial peptide microcin J25:: role of the microcin Val11-Pro16 β-hairpin region in the recognition mechanism
D Destoumieux-Garzón et al.
BIOCHEMICAL JOURNAL (2005)
Conservation of genes and processes controlled by the quorum response in bacteria:: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis
N Comella et al.
MOLECULAR MICROBIOLOGY (2005)
Amyloid formation modulates the biological activity of a bacterial protein
S Bieler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations
SM Morgan et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Competence-programmed predation of noncompletent cells in the human pathogen Streptococcus pneumoniae:: Genetic requirements
S Guiral et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
MccJ25 C-terminal is involved in RNA-polymerase inhibition but not in respiration inhibition
PA Vincent et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Structure-activity analysis of microcin J25: Distinct parts of the threaded lasso molecule are responsible for interaction with bacterial RNA polymerase
E Semenova et al.
JOURNAL OF BACTERIOLOGY (2005)
Structure of the Bacillus subtilis quorum-sensing peptide pheromone ComX
M Okada et al.
NATURE CHEMICAL BIOLOGY (2005)
Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
EW Schmidt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Penetration and interactions of the antimicrobial peptide, microcin J25, into uncharged phospholipid monolayers
A Bellomio et al.
JOURNAL OF COLLOID AND INTERFACE SCIENCE (2005)
Solution structure of the carbon storage regulator protein CsrA from Escherichia coli
P Gutiérrez et al.
JOURNAL OF BACTERIOLOGY (2005)
Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection
V Datta et al.
MOLECULAR MICROBIOLOGY (2005)
The apicoplast of Plasmodium falciparum is translationally active
S Chaubey et al.
MOLECULAR MICROBIOLOGY (2005)
Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis
MB Ekkelenkamp et al.
FEBS LETTERS (2005)
Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane
RL Lieberman et al.
NATURE (2005)
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions
M Albano et al.
JOURNAL OF BACTERIOLOGY (2005)
Solution structure of marinostatin, a natural ester-linked protein protease inhibitor
K Kanaori et al.
BIOCHEMISTRY (2005)
Ribosomal proteins in the spotlight
DN Wilson et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2005)
Bacterial lantibiotics: Strategies to improve therapeutic potential
PD Cotter et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2005)
Enterococcal cytolysin: A novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells
CR Cox et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2005)
Biosynthesis and mode of action of lantibiotics
C Chatterjee et al.
CHEMICAL REVIEWS (2005)
Interaction of thiostrepton and elongation factor-G with the ribosomal protein L11-binding domain
WS Bowen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Polytheonamides A and B, highly cytotoxic, linear polypeptides with unprecedented structural features, from the marine sponge, Theonella swinhoeiii
T Hamada et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Design, NMR characterization and activity of a 21-residue peptide fragment of bacteriocin AS-48 containing its putative membrane interacting region
MA Jimenez et al.
JOURNAL OF PEPTIDE SCIENCE (2005)
The membrane fluidity sensor DesK of Bacillus subtilis controls the signal decay of its cognate response regulator
D Albanesi et al.
JOURNAL OF BACTERIOLOGY (2004)
Structure of thermolysin cleaved microcin J25: Extreme stability of a two-chain antimicrobial peptide devoid of covalent links
KJ Rosengren et al.
BIOCHEMISTRY (2004)
Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators
ML Major et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Structure of subtilosin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to α-carbon cross-links:: Formation and reduction of α-thio-α-amino acid derivatives
KE Kawulka et al.
BIOCHEMISTRY (2004)
Evolutionary families of peptidase inhibitors
ND Rawlings et al.
BIOCHEMICAL JOURNAL (2004)
The translation initiation functions of IF2: Targets for thiostrepton inhibition
L Brandi et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics
STD Hsu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Assembly and stability of nisin-Lipid II pores
HE Hasper et al.
BIOCHEMISTRY (2004)
Methanobactin, a copper-acquisition compound from methane-oxidizing bacteria
HJ Kim et al.
SCIENCE (2004)
BI-32169, a bicyclic 19-peptide with strong glucagon receptor antagonist activity from Streptomyces sp.
O Potterat et al.
JOURNAL OF NATURAL PRODUCTS (2004)
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis
M Kleerebezem
PEPTIDES (2004)
The Enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase
LE Hancock et al.
JOURNAL OF BACTERIOLOGY (2004)
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor
S Kodani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cyanobacterial protease inhibitor microviridin J causes a lethal molting disruption in Daphnia pulicaria
T Rohrlack et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis
T Mascher et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Characterization of a gene cluster of Staphylococcus warneri ISK-1 encoding the biosynthesis of and immunity to the lantibiotic, nukacin ISK-1
Y Aso et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2004)
The microcin J25 β-hairpin region is important for antibiotic uptake but not for RNA polymerase and respiration inhibition
A Bellomio et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Enterococcus faecalis senses target cells and in response expresses cytolysin
PS Coburn et al.
SCIENCE (2004)
Targeting extracellular pyrophosphates underpins the high selectivity of nisin
BB Bonev et al.
FASEB JOURNAL (2004)
Siderophore peptide, a new type of post-translationally modified antibacterial peptide with potent activity
X Thomas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Loop deletions indicate regions important for FhuA transport and receptor functions in Escherichia coli
F Endriss et al.
JOURNAL OF BACTERIOLOGY (2004)
The role and regulation of the extracellular proteases of Staphylococcus aureus
L Shaw et al.
MICROBIOLOGY-SGM (2004)
Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing
JS Wright et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Molecular mechanism of transcription inhibition by peptide antibiotic microcin J25
K Adelman et al.
MOLECULAR CELL (2004)
Antibacterial peptide microcin J25 inhibits transcription by binding within and obstructing the RNA polymerase secondary channel
J Mukhopadhyay et al.
MOLECULAR CELL (2004)
Site-directed mutagenesis of the hinge region of nisinZ and properties of nisinZ mutants
J Yuan et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2004)
Kinetics and thermodynamics of RRF, EF-G, and thiostrepton interaction on the Escherichia coli ribosome
HS Seo et al.
BIOCHEMISTRY (2004)
Bacterial genes involved in type I secretion and sulfation are required to elicit the rice Xa21-mediated innate immune response
FG da Silva et al.
MOLECULAR PLANT-MICROBE INTERACTIONS (2004)
Thiostrepton-resistant mutants of Thermus thermophilus
DM Cameron et al.
NUCLEIC ACIDS RESEARCH (2004)
Antimitochondrial activity displayed by the antimicrobial peptide microcin J25
MVN Chirou et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Structure-function relationships of multidrug resistance P-glycoprotein
IK Pajeva et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Lipid II-mediated pore formation by the peptide antibiotic nisin: a black lipid membrane study
I Wiedemann et al.
JOURNAL OF BACTERIOLOGY (2004)
Comparative analysis of the receptor-like kinase family in Arabidopsis and rice
SH Shiu et al.
PLANT CELL (2004)
Structure of bacteriocin AS-48:: From soluble state to membrane bound state
MJ Sánchez-Barrena et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail
KA Wilson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Structure of antibacterial peptide microcin J25: A 21-residue lariat protoknot
MJ Bayro et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
The membrane-associated methane monooxygenase (pMMO) and pMMO-NADH:quinone oxidoreductase complex from Methylococcus capsulatus bath
DW Choi et al.
JOURNAL OF BACTERIOLOGY (2003)
The Enterococcus faecalis cytolysin:: a novel toxin active against eukaryotic and prokaryotic cells
PS Coburn et al.
CELLULAR MICROBIOLOGY (2003)
The action of the bacterial toxin microcin B17 - Insight into the cleavage-religation reaction of DNA gyrase
OA Pierrat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The colicin G, H and X determinants encode microcins M and H47, which might utilize the catecholate siderophore receptors FepA, Cir, Fiu and IroN
SI Patzer et al.
MICROBIOLOGY-SGM (2003)
Isolation, characterization, and quantitative analysis of microviridin J, a new Microcystis metabolite toxic to Daphnia
T Rohrlack et al.
JOURNAL OF CHEMICAL ECOLOGY (2003)
Structural basis for contrasting activities of ribosome binding thiazole antibiotics
G Lentzen et al.
CHEMISTRY & BIOLOGY (2003)
Microcin E492 antibacterial activity:: evidence for a TonB-dependent inner membrane permeabilization on Escherichia coli
D Destoumieux-Garzón et al.
MOLECULAR MICROBIOLOGY (2003)
Cannibalism by sporulating bacteria
JE Gonzalez-Pastor et al.
SCIENCE (2003)
Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin
C Szekat et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Expansion of the receptor-like kinase/Pelle gene family and receptor-like proteins in Arabidopsis
SH Shiu et al.
PLANT PHYSIOLOGY (2003)
Autoinduction and signal transduction in the regulation of staphylococcal virulence
RP Novick
MOLECULAR MICROBIOLOGY (2003)
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes
E Breukink et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Substrate-induced conformational, changes in the transmembrane segments of human P-glycoprotein - Direct evidence for the substrate-induced fit mechanism for drug binding
TW Loo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators
JD Kahmann et al.
EMBO JOURNAL (2003)
NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles - Conformational changes are a key to antimicrobial activity
STD Hsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Chemical modification of microcin J25 with diethylpyrocarbonate and carbodiimide: evidence for essential histidyl and carboxyl residues
A Bellomio et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Enterobactin: An archetype for microbial iron transport
KN Raymond et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Identification and characterization of two novel clostridial bacteriocins, circularin A and closticin 574
R Kemperman et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Cinnamycin (Ro 09-0198) promotes cell binding and toxicity by inducing transbilayer lipid movement
A Makino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The proton channel is the minimal structure of ATP synthase necessary and sufficient for microcin H47 antibiotic action
E Rodriguez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Structural and functional analysis of pantocin A: An antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes
M Jin et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Mutations of bacterial RNA polymerase leading to resistance to microcin J25
J Yuzenkova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity
A Blond et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
A central regulator of morphological differentiation in the multicellular bacterium Streptomyces coelicolor
KT Nguyen et al.
MOLECULAR MICROBIOLOGY (2002)
Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein
TW Loo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice
CD Sifri et al.
INFECTION AND IMMUNITY (2002)
Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis σW and σM regulons
M Cao et al.
MOLECULAR MICROBIOLOGY (2002)
Simultaneous detection and determination of the absolute configuration of thiazole-containing amino acids in a peptide
K Fujii et al.
TETRAHEDRON (2002)
Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus
GJ Lyon et al.
BIOCHEMISTRY (2002)
CsrA regulates glycogen biosynthesis by preventing translation of glgC in Escherichia coli
CS Baker et al.
MOLECULAR MICROBIOLOGY (2002)
Initiation factor IF2, thiostrepton and micrococcin prevent the binding of elongation factor G to the Escherichia coli ribosome
DM Cameron et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
New developments in non-post translationally modified microcins
AM Pons et al.
BIOCHIMIE (2002)
Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant
SK Park et al.
JOURNAL OF BACTERIOLOGY (2002)
Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK
M Ogura et al.
JOURNAL OF BACTERIOLOGY (2002)
Proximity of bound Hoechst 33342 to the ATPase catalytic sites places the drug binding site of P-glycoprotein within the cytoplasmic membrane leaflet
Q Qu et al.
BIOCHEMISTRY (2002)
Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines
C Hetz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Specific binding of Ro 09-0198 (cinnamycin) to phosphatidylethanotamine: A thermodynamic analysis
G Machaidze et al.
BIOCHEMISTRY (2002)
Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (Alleles), and human disease
S Jarraud et al.
INFECTION AND IMMUNITY (2002)
High genetic variability of the agr locus in Staphylococcus species
P Dufour et al.
JOURNAL OF BACTERIOLOGY (2002)
Streptolysin S and necrotising infections produced by group G streptococcus
D Humar et al.
LANCET (2002)
Two-component regulator of Enterococcus faecalis cytolysin responds to quorum-sensing autoinduction
W Haas et al.
NATURE (2002)
Inhibition of lymphocyte kinase Lck and phosphatidylinositol 3-kinase by a novel immunosuppressant, lymphostin
H Nagata et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK
RM Berka et al.
MOLECULAR MICROBIOLOGY (2002)
Characterization of comQ and comX, two genes required for production of ComX pheromone in Bacillus subtilis
KB Schneider et al.
JOURNAL OF BACTERIOLOGY (2002)
AmfS, an extracellular peptidic morphogen in Streptomyces griseus
K Ueda et al.
JOURNAL OF BACTERIOLOGY (2002)
Goadsporin, a chemical substance which promotes secondary metabolism and morphogenesis in streptomycetes - I. Purification and characterization
H Onaka et al.
JOURNAL OF ANTIBIOTICS (2001)
Goadsporin, a chemical substance which promotes secondary metabolism and morphogenesis in streptomycetes II. Structure determination
Y Igarashi et al.
JOURNAL OF ANTIBIOTICS (2001)
Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci
PM Dunman et al.
JOURNAL OF BACTERIOLOGY (2001)
Diversity of gene expression in adenocarcinoma of the lung
ME Garber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Similarities between complement-mediated and streptolysin S-mediated hemolysis
A Carr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
ATP synthase is necessary for microcin H47 antibiotic action
M Trujillo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
A spontaneous mutant of microcystin biosynthesis:: genetic characterization and effect on Daphnia
M Kaebernick et al.
ENVIRONMENTAL MICROBIOLOGY (2001)
Saposin D solubilizes anionic phospholipid-containing membranes
F Ciaffoni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structure of the Bacillus subtilis peptide antibiotic subtilosin a determined by 1H-NMR and matrix assisted laser desorption/ionization time-of-flight mass spectrometry
R Marx et al.
JOURNAL OF PROTEIN CHEMISTRY (2001)
In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites
DB Zamble et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Gelatinase biosynthesis-activating pheromone:: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis
J Nakayama et al.
MOLECULAR MICROBIOLOGY (2001)
Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus
P McDowell et al.
MOLECULAR MICROBIOLOGY (2001)
Characterization of fsr, a regulator controlling expression of gelatinase and serine protease in Enterococcus faecalis OG1RF
X Qin et al.
JOURNAL OF BACTERIOLOGY (2001)
FhuA barrel-cork hybrids are active transporters and receptors
H Killmann et al.
JOURNAL OF BACTERIOLOGY (2001)
Isolation and evaluation of nonsiderophore cyclic peptides from marine sponges
LL Guan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
The antibiotic microcin B17 is a DNA gyrase poison: Characterisation of the mode of inhibition
JG Heddle et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
K Shin-ya et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity
I Wiedemann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Pantoea agglomerans strain EH318 produces two antibiotics that inhibit Erwinia amylovora in vitro
SAI Wright et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Specificity and genetic polymorphism of the Bacillus competence quorum-sensing system
P Tortosa et al.
JOURNAL OF BACTERIOLOGY (2001)
Effects of the antibiotic peptide microcin J25 on liposomes: role of acyl chain length and negatively charged phospholipid
MR Rintoul et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)
A novel lantibiotic, nukacin ISK-1, of Staphylococcus warneri ISK-1:: Cloning of the structural gene and identification of the structure
T Sashihara et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2000)
Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus
S Jarraud et al.
JOURNAL OF BACTERIOLOGY (2000)
Bacteriocin AS-48, a microbial cyclic polypeptide structurally and functionally related to mammalian NK-lysin
C González et al.
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