Related references
Note: Only part of the references are listed.Regeneration of glomerular metabolism and function by podocyte pyruvate kinase M2 in diabetic nephropathy
Jialin Fu et al.
JCI INSIGHT (2022)
Diabetic Kidney Disease, Endothelial Damage, and Podocyte-Endothelial Crosstalk
Cindy Lora Gil et al.
KIDNEY MEDICINE (2021)
Mechanisms of Synergistic Interactions of Diabetes and Hypertension in Chronic Kidney Disease: Role of Mitochondrial Dysfunction and ER Stress
Zhen Wang et al.
CURRENT HYPERTENSION REPORTS (2020)
Targeting SHP2 as a promising strategy for cancer immunotherapy
Qianqian Liu et al.
PHARMACOLOGICAL RESEARCH (2020)
Recent Advances of SHP2 Inhibitors in Cancer Therapy: Current Development and Clinical Application
Xinrui Yuan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Prevalence and Risk Factors of Chronic Kidney Disease among Type 2 Diabetes Patients: A Cross-Sectional Study in Primary Care Practice
Janjira Jitraknatee et al.
SCIENTIFIC REPORTS (2020)
Insulin receptor endocytosis in the pathophysiology of insulin resistance
Catherine Hall et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Endogenous miR-204 Protects the Kidney against Chronic Injury in Hypertension and Diabetes
Yuan Cheng et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)
SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model
Jihong Jiang et al.
MOLECULAR MEDICINE (2020)
The Role of Podocytes and Podocyte-Associated Biomarkers in Diagnosis and Treatment of Diabetic Kidney Disease
Igor Kravets et al.
JOURNAL OF THE ENDOCRINE SOCIETY (2020)
Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling
Eunhee Choi et al.
NATURE COMMUNICATIONS (2019)
Projecting ESRD Incidence and Prevalence in the United States through 2030
Keith P. McCullough et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)
The European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report 2016: a summary
Anneke Kramer et al.
CLINICAL KIDNEY JOURNAL (2019)
Update on Diabetic Nephropathy: Core Curriculum 2018
Kausik Umanath et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2018)
Protein phosphatases and podocyte function
Pedro Geraldes
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2018)
Lentivirus-Mediated Silencing of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 2 Inhibits Release of Inflammatory Cytokines and Apoptosis in Renal Tubular Epithelial Cells Via Inhibition of the TLR4/NF-κB Pathway in Renal Ischemia-Reperfusion Injury
Jing-Fei Teng et al.
KIDNEY & BLOOD PRESSURE RESEARCH (2018)
The tyrosine phosphatase SHP2 controls TGF beta-induced STAT3 signaling to regulate fibroblast activation and fibrosis
Ariella Zehender et al.
NATURE COMMUNICATIONS (2018)
The Evolving Importance of Insulin Signaling in Podocyte Health and Disease
Abigail C. Lay et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
SHP-2 phosphatase controls aryl hydrocarbon receptor-mediated ER stress response in mast cells
Hsueh-Chun Wang et al.
ARCHIVES OF TOXICOLOGY (2017)
Protein tyrosine phosphatase 1B deficiency in podocytes mitigates hyperglycemia-induced renal injury
Yoshihiro Ito et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2017)
Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases
Andrey V. Cybulsky
NATURE REVIEWS NEPHROLOGY (2017)
Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria
Ming-Fo Hsu et al.
SCIENTIFIC REPORTS (2017)
Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor
Abigail C. Lay et al.
DIABETOLOGIA (2017)
Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor
Rodrigo Villarreal et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury
Rakesh Verma et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Insulin Increases Expression of TRPC6 Channels in Podocytes by a Calcineurin-Dependent Pathway
Shengqiang Xia et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)
Podocytes: the Weakest Link in Diabetic Kidney Disease?
Jamie S. Lin et al.
CURRENT DIABETES REPORTS (2016)
Persistent Insulin Resistance in Podocytes Caused by Epigenetic Changes of SHP-1 in Diabetes
Farah Lizotte et al.
DIABETES (2016)
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus
Jianxun Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro
Zhimei Lv et al.
JOURNAL OF DIABETES RESEARCH (2016)
Pharmacology of Src family kinases and therapeutic implications of their modulators
Amit Kumar et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2015)
Prediction of prevalence of chronic kidney disease in diabetic patients in countries of the European Union up to 2025
Alexander Kainz et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2015)
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy
Thati Madhusudhan et al.
NATURE COMMUNICATIONS (2015)
Increased SHP-1 Protein Expression by High Glucose Levels Reduces Nephrin Phosphorylation in Podocytes
Benoit Denhez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Protein Tyrosine Phosphatase 1B Inhibition Protects against Podocyte Injury and Proteinuria
Takanori Kumagai et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation
Jussara M. do Carmo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2014)
Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance
Elaine Xu et al.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2014)
Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes
Nicolas Drapeau et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease
Guillaume Canaud et al.
NATURE MEDICINE (2013)
Cell Biology and Pathology of Podocytes
Anna Greka et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)
Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice
Naoto Nagata et al.
ENDOCRINOLOGY (2012)
Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following FcεRI Aggregation
Xiaoyun Fang et al.
PLOS ONE (2012)
Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species
Eun Young Kim et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2012)
Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function
Gavin I. Welsh et al.
CELL METABOLISM (2010)
Altered Glucose Homeostasis in Mice with Liver-specific Deletion of Src Homology Phosphatase 2
Kosuke Matsuo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The activation of extracellular signal-regulated kinase is responsible for podocyte injury
Shufang Liu et al.
MOLECULAR BIOLOGY REPORTS (2010)
DIABETES Podocytes lose their footing
Christian Rask-Madsen et al.
NATURE (2010)
Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death
Frederic Princen et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
The tyrosine phosphatase Shp2 (PTPN11) in cancer
Gordon Chan et al.
CANCER AND METASTASIS REVIEWS (2008)
Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death
T. Tejada et al.
KIDNEY INTERNATIONAL (2008)
Shp2-mediated molecular signaling in control of embryonic stem cell self-renewal and differentiation
Gen-Sheng Feng
CELL RESEARCH (2007)
The human glomerular podocyte is a novel target for insulin action
RJM Coward et al.
DIABETES (2005)
Podocyte. depletion causes glomerulosclerosis: Diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
BL Wharram et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1
K Müssig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
From the periphery of the glomerular capillary wall toward the center of disease - Podocyte injury comes of age in diabetic nephropathy
G Wolf et al.
DIABETES (2005)
Src kinase regulation by phosphorylation and dephosphorylation
R Roskoski
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Shp2 regulates Src family kinase activity and Ras/Erk activation by controlling Csk recruitment
SQ Zhang et al.
MOLECULAR CELL (2004)
Treatment with insulin uncovers the motogenic capacity of nitric oxide in aortic smooth muscle cells - Dependence on Gab1 and Gab1-SHP2 association
M Dixit et al.
CIRCULATION RESEARCH (2003)
Tyrosine phosphorylation of the β3-subunit of the αVβ3 integrin is required for membrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the inslulin-like growth factor I receptor
Y Ling et al.
MOLECULAR ENDOCRINOLOGY (2003)
Development of an efficient substrate-trapping mutant of Src homology phosphotyrosine phosphatase 2 and identification of the epidermal growth factor receptor, Gab1, and three other proteins as target substrates
YM Agazie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of insulin-like growth factor I receptor dephosphorylation by SHPS-1 and the tyrosine phosphatase SHP-2
LA Maile et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats
K Isshiki et al.
DIABETES (2000)
Share Paper
