4.7 Article

TIMP1 derived from pancreatic cancer cells stimulates Schwann cells and promotes the occurrence of perineural invasion

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

EGR1-CCL2 Feedback Loop Maintains Epithelial-Mesenchymal Transition of Cisplatin-Resistant Gastric Cancer Cells and Promotes Tumor Angiogenesis

Jie Yan et al.

Summary: The EGR1-CCL2 feedback loop plays a critical role in epithelial-mesenchymal transition (EMT) and angiogenesis in chemoresistant gastric cancer (GC).

DIGESTIVE DISEASES AND SCIENCES (2022)

Article Pharmacology & Pharmacy

TIMP1 down-regulation enhances gemcitabine sensitivity and reverses chemoresistance in pancreatic cancer

Ying Tan et al.

Summary: The study revealed that TIMP1 is highly expressed in PDAC and correlated with poorer overall survival. Down-regulation of TIMP1 can enhance sensitivity of PDAC cells to GEM and reverse chemoresistance.

BIOCHEMICAL PHARMACOLOGY (2021)

Article Cell Biology

Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer

Xiaoli Ren et al.

Summary: The study revealed that monocytic MDSCs secreted CCL7 in colorectal cancer liver metastasis, activating dormant micro-metastatic cells through the JAK/STAT3 pathway. Inhibiting CCL7 and MDSCs could maintain the dormant status of CRC metastatic cells, reducing metastasis or recurrence. Elevated levels of CCL7 were associated with short-term recurrence and distant metastasis in CRC patients, highlighting the potential therapeutic strategy of targeting CCL7 for preventing metastasis recurrence.

CELL DEATH & DISEASE (2021)

Review Biochemistry & Molecular Biology

Hypoxia Alters the Expression of CC Chemokines and CC Chemokine Receptors in a Tumor-A Literature Review

Jan Korbecki et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Cell Biology

Nerves in the Tumor Microenvironment: Origin and Effects

Wenjun Wang et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Medicine, Research & Experimental

MMP1/PAR1/SP/NK1R paracrine loop modulates early perineural invasion of pancreatic cancer cells

Chumei Huang et al.

THERANOSTICS (2018)

Article Oncology

Schwann Cells Augment Cell Spreading and Metastasis of Lung Cancer

Yan Zhou et al.

CANCER RESEARCH (2018)

Editorial Material Dermatology

Research Techniques Made Simple: Analysis of Collective Cell Migration Using the Wound Healing Assay

Ayman Grada et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

Review Oncology

TIMPs: versatile extracellular regulators in cancer

Hartland W. Jackson et al.

NATURE REVIEWS CANCER (2017)

Article Integrative & Complementary Medicine

Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

Yung-Ming Chang et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)

Article Medicine, Research & Experimental

Schwann cells induce cancer cell dispersion and invasion

Sylvie Deborde et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Oncology

TIMP1 is a prognostic marker for the progression and metastasis of colon cancer through FAK-PI3K/AKT and MAPK pathway

Guohe Song et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)

Article Biochemistry & Molecular Biology

TIMP-1 modulates chemotaxis of human neural stem cells through CD63 and integrin signalling

Soo Youn Lee et al.

BIOCHEMICAL JOURNAL (2014)

Article Gastroenterology & Hepatology

Pancreatic cancer and its stroma: A conspiracy theory

Zhihong Xu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Review Multidisciplinary Sciences

Tissue Interactions in Neural Crest Cell Development and Disease

Yoshiko Takahashi et al.

SCIENCE (2013)

Article Gastroenterology & Hepatology

CCL7 and CCL21 overexpression in gastric cancer is associated with lymph node metastasis and poor prognosis

Tsann-Long Hwang et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2012)

Review Oncology

Perineural invasion and associated pain in pancreatic cancer

Aditi A. Bapat et al.

NATURE REVIEWS CANCER (2011)

Article Radiology, Nuclear Medicine & Medical Imaging

Pathways of Extrapancreatic Perineural Invasion by Pancreatic Adenocarcinoma: Evaluation With 3D Volume-Rendered MDCT Imaging

Swati D. Deshmukh et al.

AMERICAN JOURNAL OF ROENTGENOLOGY (2010)

Article Oncology

Paracrine Regulation of Pancreatic Cancer Cell Invasion by Peripheral Nerves

Ziv Gil et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)

Article Oncology

Neural Invasion in Pancreatic Cancer: The Past, Present and Future

Ihsan Ekin Demir et al.

Cancers (2010)

Review Oncology

Perineural Invasion in Cancer A Review of the Literature

Catherine Liebig et al.

CANCER (2009)

Article Biochemistry & Molecular Biology

Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein

Ki-Kyung Jung et al.

EMBO JOURNAL (2006)

Article Biochemistry & Molecular Biology

Glial cells

KR Jessen

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Gastroenterology & Hepatology

Neural invasion in the staging of pancreatic cancer

PM Pour et al.

PANCREAS (2003)