Journal
BMC INFECTIOUS DISEASES
Volume 22, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s12879-022-07688-6
Keywords
COVID-19; SARS-CoV-2 infection; Coronavirus; Neonates; Pregnant women; Prevalence
Categories
Funding
- Iran University of Medical Sciences (IUMS), Tehran, Iran
- [18462]
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This study evaluated the presence of SARS-CoV-2 infection in neonates born to mothers or relatives with COVID-19 in Iran. Out of 98 neonates studied, 6 (6.1%) tested positive for SARS-CoV-2 infection in PCR results. The study showed that the rate of COVID-19 in neonates born to mothers or relatives with SARS-CoV-2 infection in the Iranian population is about 6.1%.
Background In December 2019, in Wuhan, China, coronavirus disease 2019 (COVID-19) was emerged due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It seems that children and neonates, similar to adult and elderly individuals, are at risk of SARS-CoV-2 infection. However, adequate data are not available about neonates infected with SARS-CoV-2. Methods This study evaluated the presence of SARS-CoV-2 infection in neonates born to mothers or relatives with COVID-19. This cross-sectional study was performed on 25,044 consecutive Iranian participants in Tehran, Iran, from January 2020 to August 2020. Viral ribonucleic acid (RNA) was extracted from 500 mu l of the oropharyngeal and nasopharyngeal specimens of the participants. The genomic RNA of SARS-CoV-2 was detected by real-time polymerase chain reaction (PCR) assay. Results Out of all participants, 98 (0.40%) cases were neonates born to mothers or relatives with SARS-CoV-2 infection. Therefore, the current study was performed on these neonates. Out of 98 studied neonates, 6 (6.1%) cases had positive PCR results for SARS-CoV-2 infection. Moreover, among 98 studied neonates' mothers, 25 (25.5%) cases had positive PCR results for SARS-CoV-2 infection. Conclusion The findings of this study demonstrated that the rate of COVID-19 in neonates born to mothers or relatives with SARS-CoV-2 infection in the Iranian population is about 6.1%.
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