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ACS CHEMICAL BIOLOGY (2015)
Iron and oxidative stress in cardiomyopathy in thalassemia
Vasilios Berdoukas et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
Mai Matsushita et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Glutaminolysis and Transferrin Regulate Ferroptosis
Minghui Gao et al.
MOLECULAR CELL (2015)
Ferroptosis is Involved in Acetaminophen Induced Cell Death
Tamas Lorincz et al.
PATHOLOGY & ONCOLOGY RESEARCH (2015)
Doxorubicin Impairs the Insulin-Like Growth Factor-1 System and Causes Insulin-Like Growth Factor-1 Resistance in Cardiomyocytes
Patrizia Fabbi et al.
PLOS ONE (2015)
The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway
Ma Ruisong et al.
PLOS ONE (2015)
Blockade of mitochondrial calcium uniporter prevents cardiac mitochondrial dysfunction caused by iron overload
J. Sripetchwandee et al.
ACTA PHYSIOLOGICA (2014)
Increasing the Tolerance of DCD Hearts to Warm Ischemia by Pharmacological Postconditioning
A. Iyer et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Molecular mechanisms of diabetic cardiomyopathy
Heiko Bugger et al.
DIABETOLOGIA (2014)
Does reversible cysteine oxidation link the Western diet to cardiac dysfunction?
Jessica B. Behring et al.
FASEB JOURNAL (2014)
Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation
Yoshihiko Ichikawa et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
William E. Dowdle et al.
NATURE CELL BIOLOGY (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model
Beibei Luo et al.
PLOS ONE (2014)
Natural Killer Cells Play a Critical Role in Cardiac Allograft Vasculopathy in an Interleukin-6-Dependent Manner
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TRANSPLANTATION (2014)
Effects of iron overload on chronic metabolic diseases
Jose Manuel Fernandez-Real et al.
LANCET DIABETES & ENDOCRINOLOGY (2014)
Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation
Hong Ji et al.
BIOMEDICAL REPORTS (2014)
HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4
Jean-Marc Tadie et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase
Walter A. Baseler et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy
Raffaele Coppini et al.
CIRCULATION (2013)
Mitochondria and Endothelial Function
Matthew A. Kluge et al.
CIRCULATION RESEARCH (2013)
Implications for Interleukin-33 in solid organ transplantation
Quan Liu et al.
CYTOKINE (2013)
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Derek J. Hausenloy et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Linking endothelial dysfunction with endothelial cell activation
James K. Liao
JOURNAL OF CLINICAL INVESTIGATION (2013)
The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Official Adult Heart Transplant Report-2013; Focus Theme: Age
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JOURNAL OF HEART AND LUNG TRANSPLANTATION (2013)
Mammalian heart renewal by pre-existing cardiomyocytes
Samuel E. Senyo et al.
NATURE (2013)
Severe Sepsis and Septic Shock REPLY
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Severe Sepsis and Septic Shock
Derek C. Angus et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles
Abena S. Agyeman et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Hypoxia-Inducible Factor-1 Alpha in the Heart A Double Agent?
Satwat Hashmi et al.
CARDIOLOGY IN REVIEW (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
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CELL (2012)
Cancer and Radiation Therapy: Current Advances and Future Directions
Rajamanickam Baskar et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2012)
Identifying Sarcomere Gene Mutations in Hypertrophic Cardiomyopathy A Personal History
Christine E. Seidman et al.
CIRCULATION RESEARCH (2011)
Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression and Arachidonic Acid Metabolism in Rat Kidney and Liver
Beshay N. M. Zordoky et al.
DRUG METABOLISM AND DISPOSITION (2011)
T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice
Sirinart Kumfu et al.
EUROPEAN JOURNAL OF HAEMATOLOGY (2011)
Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization
Yumiko Kawai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy
Y. Kuwahara et al.
CELL DEATH & DISEASE (2011)
Cardiac-Specific Overexpression of HIF-1α Prevents Deterioration of Glycolytic Pathway and Cardiac Remodeling in Streptozotocin-Induced Diabetic Mice
Wanli Xue et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Modulation of the Rho/ROCK Pathway in Heart and Lung after Thorax Irradiation Reveals Targets to Improve Normal Tissue Toxicity
Virginie Monceau et al.
CURRENT DRUG TARGETS (2010)
RADIATION-RELATED HEART DISEASE: CURRENT KNOWLEDGE AND FUTURE PROSPECTS
Sarah C. Darby et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)
Iron Overload Cardiomyopathy Better Understanding of an Increasing Disorder
Pradeep Gujja et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
Masaaki Komatsu et al.
NATURE CELL BIOLOGY (2010)
Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation
Braedon McDonald et al.
SCIENCE (2010)
Mitochondrial oxidative stress and dysfunction in myocardial remodelling
Hiroyuki Tsutsui et al.
CARDIOVASCULAR RESEARCH (2009)
Reactive Oxygen Species Enhance Insulin Sensitivity
Kim Loh et al.
CELL METABOLISM (2009)
Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy
Jaya Krishnan et al.
CELL METABOLISM (2009)
Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: Role for heme oxygenase-1 down-modulation
Francesca Bernuzzi et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2009)
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-Mediated cell death
Alexander Seiler et al.
CELL METABOLISM (2008)
Mitochondria-specific transgenic overexpression of phospholipid hydroperoxide glutathione peroxidase (GPx4) attenuates ischemia/reperfusion-associated cardiac dysfunction
Erinne R. Dabkowski et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol
Marjan Boerma et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Mechanisms of sepsis-induced organ dysfunction
Edward Abraham et al.
CRITICAL CARE MEDICINE (2007)
Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure
Hiroyuki Nakayama et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity
P. Newsholme et al.
JOURNAL OF PHYSIOLOGY-LONDON (2007)
TGF-β, Smad3 and the process of progressive fibrosis
J. Gauldie et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
NATURE (2007)
Sirt1 regulates aging and resistance to oxidative stress in the heart
Ralph R. Alcendor et al.
CIRCULATION RESEARCH (2007)
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction
Julie Favre et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Expression of the MDR-1 gene-encoded P-glycoprotein in cardiomyocytes of conscious sheep undergoing acute myocardial ischemia followed by reperfusion
Ruben P. Laguens et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells
Juan P. Liuzzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation
Carsten Willam et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
M Gilchrist et al.
NATURE (2006)
Role of L-type Ca2+ channels in iron transport and iron-overload cardiomyopathy
Gavin Y. Oudit et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Contemporary definitions and classification of the cardiomyopathies - An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; And Council on Epidemiology and Prevention
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CIRCULATION (2006)
Role of natural killer cell subsets in cardiac allograft rejection
ME McNerney et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2006)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
J Oyama et al.
CIRCULATION (2004)
Pathogenesis and pathology of delayed xenograft rejection in pig-to-rhesus monkey cardiac transplantation
D Chen et al.
TRANSPLANTATION PROCEEDINGS (2004)
Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes
R Marfella et al.
DIABETES (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Regulation of transferrin receptor 2 protein levels by transferrin
A Robb et al.
BLOOD (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
Medical progress - Hereditary hemochromatosis - A new look at an old disease
A Pietrangelo
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction
T Shishido et al.
CIRCULATION (2003)
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers
S Gilles et al.
CARDIOVASCULAR RESEARCH (2003)
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
GY Oudit et al.
NATURE MEDICINE (2003)
Asymptomatic cardiac disease following mediastinal irradiation
PA Heidenreich et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma et al.
CANCER CELL (2003)
Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
P Lee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Hemochromatosis due to mutations in transferrin receptor 2
A Roetto et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
Early expression of angiogenesis factors in acute myocardial ischemia and infarction.
SH Lee et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death
J Shirani et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2000)