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Patrizia Fabbi et al.
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Ma Ruisong et al.
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J. Sripetchwandee et al.
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A. Iyer et al.
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Wan Seok Yang et al.
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Yoshihiko Ichikawa et al.
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William E. Dowdle et al.
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Jose Pedro Friedmann Angeli et al.
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Beibei Luo et al.
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Zhu-Xu Zhang et al.
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Effects of iron overload on chronic metabolic diseases
Jose Manuel Fernandez-Real et al.
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Hong Ji et al.
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HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4
Jean-Marc Tadie et al.
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Reversal of mitochondrial proteomic loss in Type 1 diabetic heart with overexpression of phospholipid hydroperoxide glutathione peroxidase
Walter A. Baseler et al.
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Matthew A. Kluge et al.
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Implications for Interleukin-33 in solid organ transplantation
Quan Liu et al.
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Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Derek J. Hausenloy et al.
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Linking endothelial dysfunction with endothelial cell activation
James K. Liao
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The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Official Adult Heart Transplant Report-2013; Focus Theme: Age
Lars H. Lund et al.
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Mammalian heart renewal by pre-existing cardiomyocytes
Samuel E. Senyo et al.
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Severe Sepsis and Septic Shock REPLY
Derek C. Angus et al.
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Severe Sepsis and Septic Shock
Derek C. Angus et al.
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Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles
Abena S. Agyeman et al.
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Scott J. Dixon et al.
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Cancer and Radiation Therapy: Current Advances and Future Directions
Rajamanickam Baskar et al.
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Christine E. Seidman et al.
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Acute Doxorubicin Toxicity Differentially Alters Cytochrome P450 Expression and Arachidonic Acid Metabolism in Rat Kidney and Liver
Beshay N. M. Zordoky et al.
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T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice
Sirinart Kumfu et al.
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Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization
Yumiko Kawai et al.
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Y. Kuwahara et al.
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Wanli Xue et al.
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Virginie Monceau et al.
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RADIATION-RELATED HEART DISEASE: CURRENT KNOWLEDGE AND FUTURE PROSPECTS
Sarah C. Darby et al.
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Pradeep Gujja et al.
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Masaaki Komatsu et al.
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Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation
Braedon McDonald et al.
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Hiroyuki Tsutsui et al.
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Reactive Oxygen Species Enhance Insulin Sensitivity
Kim Loh et al.
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Jaya Krishnan et al.
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Francesca Bernuzzi et al.
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Alexander Seiler et al.
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Erinne R. Dabkowski et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol
Marjan Boerma et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Mechanisms of sepsis-induced organ dysfunction
Edward Abraham et al.
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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure
Hiroyuki Nakayama et al.
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Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity
P. Newsholme et al.
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TGF-β, Smad3 and the process of progressive fibrosis
J. Gauldie et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
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Sirt1 regulates aging and resistance to oxidative stress in the heart
Ralph R. Alcendor et al.
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Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction
Julie Favre et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Expression of the MDR-1 gene-encoded P-glycoprotein in cardiomyocytes of conscious sheep undergoing acute myocardial ischemia followed by reperfusion
Ruben P. Laguens et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells
Juan P. Liuzzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation
Carsten Willam et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
M Gilchrist et al.
NATURE (2006)
Role of L-type Ca2+ channels in iron transport and iron-overload cardiomyopathy
Gavin Y. Oudit et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Contemporary definitions and classification of the cardiomyopathies - An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; And Council on Epidemiology and Prevention
BJ Maron et al.
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Role of natural killer cell subsets in cardiac allograft rejection
ME McNerney et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2006)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
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Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice
J Oyama et al.
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Pathogenesis and pathology of delayed xenograft rejection in pig-to-rhesus monkey cardiac transplantation
D Chen et al.
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Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes
R Marfella et al.
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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
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Regulation of transferrin receptor 2 protein levels by transferrin
A Robb et al.
BLOOD (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
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A Pietrangelo
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Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction
T Shishido et al.
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Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers
S Gilles et al.
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L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
GY Oudit et al.
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Asymptomatic cardiac disease following mediastinal irradiation
PA Heidenreich et al.
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Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma et al.
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Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo
P Lee et al.
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Hemochromatosis due to mutations in transferrin receptor 2
A Roetto et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
Early expression of angiogenesis factors in acute myocardial ischemia and infarction.
SH Lee et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death
J Shirani et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2000)
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