Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine

In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is I-pa (mu A) = 0.07701 c (mu M) - 0.1232 (R-2 = 0.996), and the linear range is 5-75 mu M. The limit of detection (LOD) and sensitivity were calculated as 0.868 mu M and 421.1 mu A/mu M, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility.

Automated summary

In this study, a selective and sensitive electrochemical sensing platform for dopamine detection was developed using CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The performance of the proposed sensor was superior to previous investigations, with simple preparation, low cost, high sensitivity, good stability, and good reproducibility.